두충나무, 황벽나무 등을 포함하는 수목추출물의 항여드름 및 항아토피 효과 = Anti-acne and Anti-atopic Dermatitis Effect of Plant Extracts Including Eucommia ulmoides Oliv and Phellodendron amurense

다국어 초록 (Multilingual Abstract)

In this study, plant extracts including Eucommia ulmoides Oliv, and Phellodendron amurense were studied to test possible application for cosmetics and skin related medicine. Anti-oxidation effect of plant extracts was measured by DPPH free radical scavenging activity and it was insignificant at low concentration, however, it was as good as vitamin C, excellent anti-oxidation agent, at 1,000 ug/ml. Anti-bacterial effect was tested by disc diffusion method, and plant extracts showed mild anti-bacterial effect for normal skin flora, Staphylococcus epidermidis while it indicated strong anti-bacterial effect for acne inducing Propionibacterium acne. Therefore it had powerful potential for anti-acne material because of selectivity. Anti-atopic dermatitis effect was tested by hairless mouse and plant extracts recovered damaged skin to near normal condition after 14 days of treatment. IgE concentration in treated mouse was decreased 16% compared with control. From the research, plant extracts indicated strong anti-acne and anti-atopic dermatitis effect, and showed strong potential for cosmetics and skin related medicine.

참고문헌 (Reference)

1 Park, J. C, Hyoilbooks 2007

2 윤경섭, "황기추출물의 항노화 효과" 대한화장품학회 33 (33): 33-40, 2007

3 박수남, "제주 자생 식물 추출물의 항산화 및 항노화에 관한 연구(II)" 대한화장품학회 33 (33): 165-173, 2007

4 Korea Food and Drug Administration, "http://www.kfda.go.kr/index.html"

5 "http://en.wikipedia.org/wiki/Traditional_Chinese_medicine."

6 "http://en.wikipedia.org/wiki/Berberine"

7 Ahn, B. K, "The Pathogenesis of Acne" 4 : 62-70, 2002

8 Yamato, A, "Stratum Corneum Lipid Abnormalities in Atopic Dermatitis" 283 : 219-223, 1991

9 Association of Official Analytical Chemists, "Official Methods of Analysis, 15th ed" A.O.A.C 1990

10 Pharmacognosy Researchers, "Modern pharmacognosy" Hak Chan Publishing 2000

11 KDA Textbook Editing Board, "Dermatology, 5th ed." Ryo Mook Gak 2008

12 Choi, H. J, "Cosmetics Industry Analytical Report" Korea Health Industry Development Institute 2008

13 Ahn, S. Y, "Atopic Dermatitis and Skin Barrier" 8 : 47-51, 2006

14 Kang, K. J, "Anti-atopic Dermatitis Effect of Prunus Yedoensis Matsum Bark Extract" College of Medicine, Jeju University 2006

15 Choi, E. H, "Acne and Skin Barrier" 8 : 42-46, 2006