Microcystic adnexal carcinoma (MAC) is an extremely uncommon, low-grade but locally aggressive neoplasm of eccrine sweat glands. A 66-year-old male presented with an 8-year history of an asymptomatic slowly growing tumor on his left pubic area. The le...
Microcystic adnexal carcinoma (MAC) is an extremely uncommon, low-grade but locally aggressive neoplasm of eccrine sweat glands. A 66-year-old male presented with an 8-year history of an asymptomatic slowly growing tumor on his left pubic area. The lesion was a fleshy to pinkish, cauliflower-like solitary mass measuring 1 X 1.5 cm in size. A skin biopsy revealed a poorly circumscribed, deeply infiltrating tumor consisted of islands and strands of squamoid or basaloid cells in dermis. In immunohistochemical analysis, the tumor cells were positive for EMA, CK7 and GCDFP-15, but negative for CK5/6, CD15, and S-100. He was finally diagnosed with MAC. The mass was successfully excised by Mohs micrographic surgery with clear resection margins. MAC is known to occur primarily in Caucasians and rarely in non-Caucasians. Histology is essential in diagnosis due to its clinical appearance and course mimicking other disorders. Based on the extending nature of MAC, Mohs micrographic surgery is the treatment of choice for good prognosis. This is a case of MAC on pubis successfully treated by Mohs micrographic surgery, which is one of the rare cases among non-Caucasians.