Fluorescent detection of insitu hypridization(FISH) with whole chromosome painting probe(chromosome 2 and 6) has used to assess the use of this method for preimplatation diagnosis of the carrier of a balanced traslocation t(2;6)(p13;p21) which has rep...
Fluorescent detection of insitu hypridization(FISH) with whole chromosome painting probe(chromosome 2 and 6) has used to assess the use of this method for preimplatation diagnosis of the carrier of a balanced traslocation t(2;6)(p13;p21) which has repeatedly led to spontaneous abortions. Interphase nuclei have been analyzed and four embryos with 2 green/red signals each for the chromosome 2 and 6 were transferred and a pregnancy resulted.