<P><B>Objective:</B></P><P>To evaluate the vascular response at 9 months after zotarolimus-eluting stent (ZES; Endeavor) implantation using optical coherence tomography (OCT). These findings were compared with those after...
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https://www.riss.kr/link?id=A107626742
2009
-
SCI,SCIE,SCOPUS
학술저널
1907-1912(6쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P><B>Objective:</B></P><P>To evaluate the vascular response at 9 months after zotarolimus-eluting stent (ZES; Endeavor) implantation using optical coherence tomography (OCT). These findings were compared with those after...
<P><B>Objective:</B></P><P>To evaluate the vascular response at 9 months after zotarolimus-eluting stent (ZES; Endeavor) implantation using optical coherence tomography (OCT). These findings were compared with those after implantation of a sirolimus-eluting stent (SES; Cypher Select).</P><P><B>Design:</B></P><P>Cross-sectional observational study with prospective OCT registry.</P><P><B>Setting:</B></P><P>Nine months after ZES or SES implantation.</P><P><B>Patients and methods:</B></P><P>A total of 68 patients (32 ZES and 36 SES) underwent OCT at 9 months after stent implantation. The neointima hyperplasia (NIH) thickness inside each strut and percentage of NIH area at every 1 mm cross section were measured.</P><P><B>Main outcome measurement:</B></P><P>The degree of neointimal coverage and the prevalence of malapposition at 9 months after ZES and SES implantation using OCT.</P><P><B>Results:</B></P><P>The mean (SD) NIH thickness (251.2 (110.0) μm vs 85.5 (53.3) μm, p<0.001) and percentage of NIH area (27.9 (9.1)% vs 11.2 (7.1)%, p<0.001) were significantly greater in ZES than in SES. The prevalence of uncovered strut as well as malapposed strut was significantly lower in ZES than in SES (0.3% vs 12.3%, p<0.001 and 0.08% vs 2.6%, p<0.001). Thrombus was not observed in ZES (0.0% in ZES vs 27.8% in SES, p = 0.001).</P><P><B>Conclusions:</B></P><P>Neointimal coverage in ZES was almost complete and malapposition was very rare at 9-months’ follow-up.</P>