가토 악골에 매식된 Apatite-Wollastonite Glass Ceramic의 생체반응에 관한 실험적 연구 = An Experimental Study on Apatite Wollastonite Glass Ceramic implanted in the Rabbit Maxillae

다국어 초록 (Multilingual Abstract)

The authors implanted the Apatite Wollastonite Glass Ceramic(AWGC) powders in the rabbit maxillae to evaluate the possibility of clinical use as an artificial bone substitute material. Firstly we made AWGC and analized powder X-ray diffraction pattern of glass after crystalization. Secondly we made animal experiment with New Zealand white rabbits. The rabbits were sacrificed at the day of opstoperative 2 weeks and 4 weeks after implantation. We took the radiography of the maxillae block specimens, each of which includes the AWGC, at the day of sacrifice. And the block specimens were routinely prepared for the SEM and EDX study. We observed the attitudes at the border between the bone and the material with the SEM, and we searched the components such as Ca or P by use of EDX and compared the periodic changing data. The obtained results are as follows :
1. On SEM findings, silica band-like zone was found between the bone and the implanted materials at 2-week specimen, and this zone was found diffusely mingled between the bone and the implanted meterials at the 4-week specimen.
2. On intraoral X-ray findings, the border line was definitely found between the bone and the the material just after implantation of AWGC, but the border line became difused and fusion was occasionally found at the border area.
3. There was a little change in the natural bone components at the border area, and Ca or P was drawn out from Awgc at the border area.
4. Si of AWGC was increased as the time being, and AWGC was dissolved with leakage of Ca and P.
So it is suggested that the intermediate zone of Calcium Phosphate Apatite was formed at the border area by Ca and P from AWGC dissolution, and it makes AWGC further tightly bonded to the bone.

목차 (Table of Contents)

• Ⅰ. 서 론
• Ⅱ. 연구대상 및 방법
• Ⅲ. 연구 결과 및 고안
• Ⅳ. 결 론