정제봉독을 함유한 봉독화장품의 피부주름 개선 효과 = The Effect of Cosmetic Included Purified Bee Venom on the Improvement of Skin Wrinkle

다국어 초록 (Multilingual Abstract)

In the last few decades, there has been a substantial increase in the population of aged people. Aging skin is a common concern for many people theses days. The purpose of this study was to evaluate the efficacy of serum containing purified bee venom in reducing wrinkles. Bee venom serum was applied to the face after toner of 22 subjects twice a day for 12 weeks The changes of the skin wrinkles were analyzed with the visual grade of wrinkle and the image of the skin replica. Compared to before and after treatment, the visual grade of wrinkle was improved 11.83% after 12 weeks. The wrinkle squares and depths were significantly reduced after 12 weeks(p<0.05). Also, the wrinkle counts were significantly reduced after 12 weeks(p<0.5). Adverse reactions of subjects were not observed during the course of the study. These observations indicate that the treatment of purified bee venom seems to be effective in improving wrinkles and can be usefully tho the anti-aging cosmetic industry.