1 Doench JG, "siRNAs can function as miRNAs" 17 : 438-442, 2003
2 Yang S, "miR-21 regulates chronic hypoxia-induced pulmonary vascular remodeling" 302 : L521-L529, 2012
3 Simonneau G, "Updated clinical classification of pulmonary hypertension" 54 (54): S43-S54, 2009
4 Mittelbrunn M, "Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells" 2 : 282-, 2011
5 Ma L, "Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model" 28 : 341-347, 2010
6 Montgomery RL, "Therapeutic advances in MicroRNA targeting" 57 : 1-7, 2011
7 Guo L, "The microRNA-328 regulates hypoxic pulmonary hypertension by targeting at insulin growth factor 1 receptor and L-type calcium channel-α1C" 59 : 1006-1013, 2012
8 Krutzfeldt J, "Silencing of microRNAs in vivo with ‘antagomirs’" 438 : 685-689, 2005
9 Zhang Y, "Secreted monocytic miR-150 enhances targeted endothelial cell migration" 39 : 133-144, 2010
10 Urbich C, "Role of microRNAs in vascular diseases, inflammation, and angiogenesis" 79 : 581-588, 2008
11 Courboulin A, "Role for miR-204 in human pulmonary arterial hypertension" 535-548, 2011
12 Brodersen P, "Revisiting the principles of microRNA target recognition and mode of action" 10 : 141-148, 2009
13 Zhao YD, "Rescue of monocrotaline-induced pulmonary arterial hypertension using bone marrow-derived endothelial-like progenitor cells: efficacy of combined cell and eNOS gene therapy in established disease" 96 : 442-450, 2005
14 Rhodes CJ, "Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension" 294-302, 2013
15 Farber HW, "Pulmonary arterial hypertension" 351 : 1655-1665, 2004
16 McLaughlin VV, "Pulmonary arterial hypertension" 36 : 461-517, 2011
17 Lewis BP, "Prediction of mammalian microRNA targets" 115 : 787-798, 2003
18 Eddahibi S, "Polymorphism of the serotonin transporter gene and pulmonary hypertension in chronic obstructive pulmonary disease" 108 : 1839-1844, 2003
19 Cheng CJ, "Polymer nanoparticle-mediated delivery of microRNA inhibition and alternative splicing" 9 : 1481-1488, 2012
20 Bockmeyer CL, "Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression" 31 : 764-772, 2012
21 Small EM, "Pervasive roles of microRNAs in cardiovascular biology" 469 : 336-342, 2011
22 Tuder RM, "Pathology of pulmonary arterial hypertension" 30 : 376-385, 2009
23 Chan SY, "Pathogenic mechanisms of pulmonary arterial hypertension" 44 : 14-30, 2008
24 Carthew RW, "Origins and mechanisms of miRNAs and siRNAs" 136 : 642-655, 2009
25 Esteller M, "Non-coding RNAs in human disease" 12 : 861-874, 2011
26 Babar IA, "Nanoparticle-based therapy in an in vivo microRNA-155 (miR-155)-dependent mouse model of lymphoma" 109 : E1695-E1704, 2012
27 Newman JH, "Mutation in the gene for bone morphogenetic protein receptor II as a cause of primary pulmonary hypertension in a large kindred" 345 : 319-324, 2001
28 Friedman RC, "Most mammalian mRNAs are conserved targets of microRNAs" 19 : 92-105, 2009
29 Jeffery TK, "Molecular and cellular basis of pulmonary vascular remodeling in pulmonary hypertension" 45 : 173-202, 2002
30 Vickers KC, "MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins" 13 : 423-433, 2011
31 Bartel DP, "MicroRNAs : target recognition and regulatory functions" 136 : 215-233, 2009
32 Chan SY, "MicroRNA-210 : a unique and pleiotropic hypoxamir" 9 : 1072-1083, 2010
33 Parikh VN, "MicroRNA-21 integrates pathogenic signaling to control pulmonary hypertension : results of a network bioinformatics approach" 125 : 1520-1532, 2012
34 Thum T, "MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts" 456 : 980-984, 2008
35 Care A, "MicroRNA-133 controls cardiac hypertrophy" 613-618, 2007
36 Liu N, "MicroRNA regulatory networks in cardiovascular development" 18 : 510-525, 2010
37 Filipowicz W, "Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?" 9 : 102-114, 2008
38 Schermuly RT, "Mechanisms of disease : pulmonary arterial hypertension" 8 : 443-455, 2011
39 Mercer TR, "Long non-coding RNAs : insights into functions" 10 : 155-159, 2009
40 Brock M, "Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway" 104 : 1184-1191, 2009
41 Pullamsetti SS, "Inhibition of microRNA-17 improves lung and heart function in experimental pulmonary hypertension" 185 : 409-419, 2012
42 Kuwabara Y, "Increased microRNA-1 and microRNA-133a levels in serum of patients with cardiovascular disease indicate myocardial damage" 4 : 446-454, 2011
43 Frid MG, "Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineage" 168 : 659-669, 2006
44 Maynard MA, "Human HIF-3alpha4 is a dominant-negative regulator of HIF-1 and is down-regulated in renal cell carcinoma" 19 : 1396-1406, 2005
45 White K, "Holding our breath : the emerging and anticipated roles of microRNA in pulmonary hypertension" 2 : 278-290, 2012
46 International PPH Consortium, "Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension" 26 : 81-84, 2000
47 Adams JM, "HIF-1 : a key mediator in hypoxia" 96 : 19-28, 2009
48 Shimoda LA, "HIF and the lung : role of hypoxia-inducible factors in pulmonary development and disease" 183 : 152-156, 2011
49 Pegtel DM, "Functional delivery of viral miRNAs via exosomes" 107 : 6328-6333, 2010
50 Valadi H, "Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells" 9 : 654-659, 2007
51 Archer SL, "Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension : a basis for excessive cell proliferation and a new therapeutic target" 121 : 2661-2671, 2010
52 Budhiraja R, "Endothelial dysfunction in pulmonary hypertension" 109 : 159-165, 2004
53 Fabani MM, "Efficient inhibition of miR-155 function in vivo by peptide nucleic acids" 38 : 4466-4475, 2010
54 Caruso P, "Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline" 30 : 716-723, 2010
55 Wang V, "Differential gene up-regulation by hypoxia-inducible factor-1alpha and hypoxia-inducible factor-2alpha in HEK293T cells" 65 : 3299-3306, 2005
56 Abdellatif M, "Differential expression of microRNAs in different disease states" 110 : 638-650, 2012
57 Lawrie CH, "Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma" 141 : 672-675, 2008
58 Zernecke A, "Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection" 2 : ra81-, 2009
59 Lourenco AP, "Current pathophysiological concepts and management of pulmonary hypertension" 155 : 350-361, 2012
60 Lewis BP, "Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets" 120 : 15-20, 2005
61 Xu J, "Circulating microRNAs: novel biomarkers for cardiovascular diseases" 90 : 865-875, 2012
62 Creemers EE, "Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?" 110 : 483-495, 2012
63 Fichtlscherer S, "Circulating microRNAs: biomarkers or mediators of cardiovascular diseases?" 31 : 2383-2390, 2011
64 Mitchell PS, "Circulating microRNAs as stable blood-based markers for cancer detection" 105 : 10513-10518, 2008
65 Lennox KA, "Chemical modification and design of anti-miRNA oligonucleotides" 18 : 1111-1120, 2011
66 Chen X, "Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases" 18 : 997-1006, 2008
67 Morrell NW, "Cellular and molecular basis of pulmonary arterial hypertension" 54 (54): S20-S31, 2009
68 Weidemann A, "Biology of HIF-1alpha" 15 : 621-627, 2008
69 Archer SL, "Basic science of pulmonary arterial hypertension for clinicians : new concepts and experimental therapies" 121 : 2045-2066, 2010
70 Hammond SM, "Argonaute2, a link between genetic and biochemical analyses of RNAi" 293 : 1146-1150, 2001
71 Arroyo JD, "Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma" 108 : 5003-5008, 2011
72 Brock M, "AntagomiR directed against miR-20a restores functional BMPR2 signalling and prevents vascular remodelling in hypoxia-induced pulmonary hypertension" 26 : 2012
73 Alexander RP, "Annotating non-coding regions of the genome" 11 : 559-571, 2010
74 Kim J, "An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension" 19 : 74-82, 2013
75 Caruso P, "A role for miR-145 in pulmonary arterial hypertension: evidence from mouse models and patient samples" 111 : 290-300, 2012