This study describes the synthesis of novel enol esters (3) and triketones (4) as analogues of
succinylacetone (SA) (Ed- this abbreviation is introduced here based on your use of it in the
body of the paper) and the evaluation on the mouse allogeneic ...
This study describes the synthesis of novel enol esters (3) and triketones (4) as analogues of
succinylacetone (SA) (Ed- this abbreviation is introduced here based on your use of it in the
body of the paper) and the evaluation on the mouse allogeneic mixed lymphocyte reaction
(MLR) and the murine model of antigen-induced paw edema formation for immunosuppressive
activity. Enol esters (3a-f) were about 2-4 fold more potent than SA in in vitro activity.