<P>We present a feasible method to collect ferromagnetic nanomaterials(FNMs) after clinical utilization by employing ferromagnetic microcontainers (MCs). The cubic MCs with dimensions of 200 micrometers have gold-coated nickel frames and were te...
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https://www.riss.kr/link?id=A107671091
2013
-
SCOPUS,SCIE
학술저널
3464-3467(4쪽)
0
상세조회0
다운로드다국어 초록 (Multilingual Abstract)
<P>We present a feasible method to collect ferromagnetic nanomaterials(FNMs) after clinical utilization by employing ferromagnetic microcontainers (MCs). The cubic MCs with dimensions of 200 micrometers have gold-coated nickel frames and were te...
<P>We present a feasible method to collect ferromagnetic nanomaterials(FNMs) after clinical utilization by employing ferromagnetic microcontainers (MCs). The cubic MCs with dimensions of 200 micrometers have gold-coated nickel frames and were tethered such a way that they are able to remove FNMs from cells with the use of an external magnetic field. The study has been conducted in two parts: 1) enhancement of the motion of MCs in glass-based microfluidic channels filled with viscous fluids by magnetically-driven spinning MCs, i.e., “dynamic MCs”; 2)sweeping FNMs from the cells using magnetic attractive forces between FNMs and MCs through a “microvacuum”process. Our study shows that spinning MCs can transport better than nonspinning MCs through viscous fluids. We found that approximately 70% of FNMs internalized with human embryonic cells (HEK-293) were removed from the cells by the spinning MCs. Such in-vitro experiments suggest the possibility of resolving the issue of removing FNMs used for clinical treatments from human body after treatments.</P>
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