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      급성 중증 유기인계 중독 환자의 예후 판정을 위한 Scoring Methods = Scoring Methods for Prognosis of Patients with Acute Severe Organophosphate Intoxication

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      https://www.riss.kr/link?id=A104608801

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      Purpose: Although, there have been many reports about
      factors involved in the severity and prognosis of
      organophosphate toxicity, there are few reports on integrated
      application of scoring methods using those factors for
      prognosis. Our report is about the possible application of
      such scoring methods in the early stage of organophosphate
      intoxication.
      Methods: This study included organophosphate intoxication
      patients who were admitted to the Emergency department
      (ED) between March 1, 2004 and February 28, 2008.
      We limited enrolment in the study to patients who had
      required assisted mechanical ventilation and used atropine
      for therapy. This was a retrospective study about age, drug
      toxicity, mental status, existence of metabolic acidosis and
      QT prolongation for each patient.
      Results: Thirty seven patients were enrolled in this study.
      Among the 37, 22 survived and 15 died. For survivors, drug
      toxicity and mental status were correlated with total dose of
      atropine, and the existence of metabolic acidosis was correlated
      with the duration of mechanical ventilation. Survivors
      had lower total scores than non-survivors.
      Conclusion: Application of scoring methods that include
      five factors (age, drug toxicity, mental status, existence of
      metabolic acidosis, existence of QTc prolongation) when
      acute, severe, organophosphate poisoning patients arrive
      at an ED can be helpful for their prognosis.
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      Purpose: Although, there have been many reports about factors involved in the severity and prognosis of organophosphate toxicity, there are few reports on integrated application of scoring methods using those factors for prognosis. Our report is about...

      Purpose: Although, there have been many reports about
      factors involved in the severity and prognosis of
      organophosphate toxicity, there are few reports on integrated
      application of scoring methods using those factors for
      prognosis. Our report is about the possible application of
      such scoring methods in the early stage of organophosphate
      intoxication.
      Methods: This study included organophosphate intoxication
      patients who were admitted to the Emergency department
      (ED) between March 1, 2004 and February 28, 2008.
      We limited enrolment in the study to patients who had
      required assisted mechanical ventilation and used atropine
      for therapy. This was a retrospective study about age, drug
      toxicity, mental status, existence of metabolic acidosis and
      QT prolongation for each patient.
      Results: Thirty seven patients were enrolled in this study.
      Among the 37, 22 survived and 15 died. For survivors, drug
      toxicity and mental status were correlated with total dose of
      atropine, and the existence of metabolic acidosis was correlated
      with the duration of mechanical ventilation. Survivors
      had lower total scores than non-survivors.
      Conclusion: Application of scoring methods that include
      five factors (age, drug toxicity, mental status, existence of
      metabolic acidosis, existence of QTc prolongation) when
      acute, severe, organophosphate poisoning patients arrive
      at an ED can be helpful for their prognosis.

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      참고문헌 (Reference)

      1 진우제, "기계 환기를 요한 유기인계 농약 중독환자의 임상 독성학적 특성" 대한응급의학회 15 (15): 554-560, 2004

      2 Bilgin TE, "The comparison of the efficacy of scoring systems in organophosphate poisoning" 21 : 141-146, 2005

      3 Marino PL, "The ICU book. 3nd ed" Lippincott William & Wilkins 531-544, 2007

      4 Gunnell D, "Suicide by intentional ingestion of pesticides: a continuing tragedy in developing countries" 32 : 902-909, 2003

      5 Aygun D, "Serum acetylcholinesterase and prognosis of acute organophosphate poisoning" 40 : 903-910, 2002

      6 Chuang FR, "QTc prolongation indicates a poor prognosis in patients with organophosphate poisoning" 14 : 451-453, 1996

      7 Nouira S, "Prognostic value of serum cholinesterase in organophosphate poisoning" 106 : 1811-1814, 1994

      8 Nouira S, "Prognostic value of serum cholinesterase in organophosphate poisoning" 106 : 1811-1814, 1994

      9 Namba T, "Poisoning due to organophosphate insecticides. Acute and chronic manifestations" 50 : 475-492, 1971

      10 Lee SJ, "Is it meaningful to use the serum cholinesterase level as a predictive value in acute organophosphate poisoning?" 2 : 72-76, 2004

      1 진우제, "기계 환기를 요한 유기인계 농약 중독환자의 임상 독성학적 특성" 대한응급의학회 15 (15): 554-560, 2004

      2 Bilgin TE, "The comparison of the efficacy of scoring systems in organophosphate poisoning" 21 : 141-146, 2005

      3 Marino PL, "The ICU book. 3nd ed" Lippincott William & Wilkins 531-544, 2007

      4 Gunnell D, "Suicide by intentional ingestion of pesticides: a continuing tragedy in developing countries" 32 : 902-909, 2003

      5 Aygun D, "Serum acetylcholinesterase and prognosis of acute organophosphate poisoning" 40 : 903-910, 2002

      6 Chuang FR, "QTc prolongation indicates a poor prognosis in patients with organophosphate poisoning" 14 : 451-453, 1996

      7 Nouira S, "Prognostic value of serum cholinesterase in organophosphate poisoning" 106 : 1811-1814, 1994

      8 Nouira S, "Prognostic value of serum cholinesterase in organophosphate poisoning" 106 : 1811-1814, 1994

      9 Namba T, "Poisoning due to organophosphate insecticides. Acute and chronic manifestations" 50 : 475-492, 1971

      10 Lee SJ, "Is it meaningful to use the serum cholinesterase level as a predictive value in acute organophosphate poisoning?" 2 : 72-76, 2004

      11 Yamashita M, "Human mortality in organophosphate poisonings" 39 : 84-85, 1997

      12 Grmec S, "Glasgow Coma Scale score and QTc interval in the prognosis of organophoaphate poisoning" 11 : 925-930, 2004

      13 Ha YR, "Early prognostic factor and new approach to organophosphate poisoning" 9 : 142-147, 1998

      14 Chun BJ, "Clinical significance of immediate determination of plasma cholinesterase level in patients presenting with organophosphate ingestion at the time of hospitalization" 13 : 61-66, 2002

      15 Kim H, "Clinical implication of acetylcholinesterase in acute organophosphate poisoning" 6 : 25-31, 2008

      16 Lee P, "Clinical features of patients with acute organophosphate poisoning requiring intensive care" 27 : 694-699, 2001

      17 Liu JH, "Acid-base interpretation can be the predictor of outcome among patients with acute organophosphate poisoning before hospitalization" 26 : 24-30, 2008

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      학술지 이력

      학술지 이력
      연월일 이력구분 이력상세 등재구분
      2027 평가예정 재인증평가 신청대상 (재인증)
      2021-01-01 평가 등재학술지 유지 (재인증) KCI등재
      2020-05-08 학회명변경 영문명 : The Korean Society Of Emergency Medicine -> The Korean Society of Emergency Medicine KCI등재
      2018-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2015-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2011-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2009-01-01 평가 등재학술지 유지 (등재유지) KCI등재
      2006-01-01 평가 등재학술지 선정 (등재후보2차) KCI등재
      2005-01-01 평가 등재후보 1차 PASS (등재후보1차) KCI등재후보
      2003-01-01 평가 등재후보학술지 선정 (신규평가) KCI등재후보
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      학술지 인용정보

      학술지 인용정보
      기준연도 WOS-KCI 통합IF(2년) KCIF(2년) KCIF(3년)
      2016 0.23 0.23 0.22
      KCIF(4년) KCIF(5년) 중심성지수(3년) 즉시성지수
      0.22 0.22 0.339 0.06
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