캔 제품의 bisphenol A diglycidyl ether (BADGE), bisphenol F diglycidyl ether (BFDGE) 유도체 및 분해산물 분석법

국문 초록 (Abstract)

캔제품 중 Biphenol A diglycidyl ether(BADGE), bisphenol F diglycidyl ether(BFDGE) 및 그 분해산물인 BADGE·H₂O, BADGE·2H₂O, BADGE·HCl, BADGE·2HCl, BADGE·HCl·H₂O, BFDGE·H₂O, BFDGE·2H₂O, BFDGE·HCl, BFDGE·2HCl, BFDGE·HCl·H₂O 등의 HPLC/FLD와 HPLC/APCI-MS에 의한 정성 및 정량방법을 확립하고 133개 캔 제품을 사용하여 분석방법의 재현성을 검토하였다. 수용성 식품의 경우 BADGE·2H2O가 13개 제품에서 0.400-0.888 mg/kg, BADGE·HCl·H2O가 1개 제품에서 0.566mg/kg, BFDGE·H2O가 3개 제품에서 0.489-0.664 mg/kg, BFDGE·2H2O가 3개 제품에서 0.455-0.846 mg/kg, BFDGE·HCl·H2O가 2개 제품에서 0.455-0.752 mg/kg의 농도로 검출되었다. 지용성 식품의 경우에는 BADGE가 3개 제품에서 0.093-0.486 mg/kg, BADGE·H2O가 1개 제품에서 0.183 mg/kg, BADGE·HCl이 1개 제품에서 0.097 mg/kg, BADGE·2HCl이 7개 제품에서 0.200-0.452 mg/kg, BFDGE가 3개 제품에서 0.438-0.506 mg/kg, BFDGE·2H2O가 1개 제품에서 0.295 mg/kg, BFDGE·HCl 및 BFDGE·2HCl이 1개 제품에서 0.324 mg/kg의 농도로 검출되었다. 분석방법의 재현성은 우수하였고, 모니터링 결과는 EU 수준과 유사하거나 안전한 수준으로 나타났다.

다국어 초록 (Multilingual Abstract)

Bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) were obtained by a polymerization reaction of epichlorohydrin (ECH) with bisphenol A (BPA) or bisphenol F (BPF). These compounds are commonly used as monomers or additives such as a polymerization stabilizer and a hydrochloric acid scavenger of epoxy resin, polyvinyl chloride (PVC)-containing organosols and polyester lacquers, that are applied to the internal surface of most canned foods to impart chemical resistance. The unreacted BADGE, BFDGE and their reaction products migrating from epoxy resin, PVC-containing organosol and/or polyester lacquer-based food packaging materials into the foods have recently become an issue of great concern because of increased customer demand for safety. This study was conducted to develop a rapid and sensitive simultaneous analysis method based on HPLC/FLD and HPLC/APCI-mass and to evaluate the concentration of BADGE, BFDGE and their metabolites, BADGE·H₂O, BADGE·2H₂O, BADGE·HCl, BADGE·2HCl, BADGE·HCl·H₂O, BFDGE·H₂O, BFDGE·2H₂O, BFDGE·HCl, BFDGE·2HCl and BFDGE·HCl·H₂O for 133 canned food samples. The method provided a linearity of 0.9997-0.9999, a limit of detection of 0.01-0.13 μg/mL, a limit of quantitation of 0.03-0.44 μg/mL and a recovery (%) of 85.64-118.18. The number of samples containing BADGE, BFDGE or their metabolites were: 28/133 (21.1%), with levels of 0.400-0.888 mg/kg being observed for aqueous foods (19/133) and 0.093-0.506 mg/kg being observed for oily foods (9/133).

목차 (Table of Contents)

• Abstract
• 서론
• 재료 및 방법
• 결과 및 고찰
• 요약
• 문헌

참고문헌 (Reference)

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