Enhancement of antioxidative and antimicrobial activities of immature pear (Pyrus pyrifolia cv. Niitaka) fruits by fermentation with Leuconostoc mesenteroides

다국어 초록 (Multilingual Abstract)

Immature pear (Pyrus pyrifolia cv. Niitaka) fruits were fermented with Leuconostoc mesenteroides and Aspergillus oryzae, which are commonly used as starters for manufacturing fermented foods. Fermented immature pear fruit extracts (FIPF) by L. mesenteroides showed significantly higher radical-scavenging activity using DPPH, ABTS, superoxide anion, and hydroxyl radicals and reducing power capacity than unfermented immature pear fruit extracts. L.
mesenteroides-FIPF more effectively inhibited the formation of cholesteryl ester hydroperoxide in copper ion-induced rat blood plasma. In addition, the L. mesenteroides-FIPF strongly inhibited tyrosinase activity and the growth of pathogenic skin bacteria. In contrast, enhanced antioxidative and antibacterial activities were not apparent in A. oryzae-FIPF. The antioxidative and antimicrobial activities of the fermented and unfermented immature pear fruits were correlated with the flavonoid contents. These results indicate that fermentation enhances antioxidative and antimicrobial activities of immature pear fruits.

참고문헌 (Reference)

1 이유건, "추황배(Pyrus pyrifolia Nakai cv. Chuhwangbae) 과피로부터 3종의 저분자 화합물의 단리·동정" 한국식품과학회 45 (45): 174-179, 2013

2 Langston J, "Substrate specificity of Aspergillus oryzae family 3β-glucosidase" 1764 : 972-978, 2006

3 Lee SW, "Study on availability of immature pear fruits: Bioactivity of fermented product and large-scale purification of arbutin" Chonnam National University 2015

4 Oyaizu M, "Studies on products of browning reactions: Antioxidative activities of products of browning reaction prepared from glucosamine" 44 : 307-315, 1986

5 Zaika LZ, "Spices and herbs. Their antimicrobial activity and its determination" 9 : 97-118, 1998

6 Cogen AL, "Skin microbiota: A source of disease or defence?" 158 : 442-455, 2008

7 조정용, "Recovery of Arbutin in High Purity from Fruit Peels of Pear (Pyrus pyrifolia Nakai)" 한국식품과학회 20 (20): 801-807, 2011

8 Yamamoto Y, "Presence of cholesteryl ester hydroperoxides in human blood plasma" 165 : 988-993, 1989

9 Tanrioven D, "Phenolic compounds in pear juice from different cultivars" 93 : 89-93, 2005

10 Lin LZ, "Phenolic compounds and chromatographic profiles of pear skins (Pyrus spp.)" 56 : 9094-9101, 2008

11 Kim JY, "Nonallergenic urushiol derivatives inhibit the oxidation of unilamellar vesicles and of rat plasma induced by various radical generators" 71 : 379-389, 2014

12 Merken HM, "Measurement of food flavonoids by highperformance liquid chromatography: A review" 48 : 577-599, 2000

13 이유건, "Large-scale Isolation of Highly Pure Malaxinic Acid from Immature Pear (Pyrus pyrifolia Nakai) Fruit" 한국식품과학회 22 (22): 1539-1545, 2013

14 이기훈, "Isolation and Identification of Phenolic Compounds from an Asian Pear (Pyrus pyrifolia Nakai) Fruit Peel" 한국식품과학회 20 (20): 1539-1545, 2011

15 Lee KH, "Hydroxycinnamoylmalic acids and their methyl esters from pear (Pyrus pyrifolia Nakai) fruit peel" 59 : 10124-10128, 2011

16 Slavin JL, "Health benefits of fruits and vegetables" 3 : 506-516, 2012

17 Prior RL, "Fruits and vegetables in the prevention of cellular oxidative damage" 78 : 570-578, 2003

18 Orhan IE, "Flavonoid derivatives as potent tyrosinase inhibitors - a survey of recent findings between 2008-2013" 14 : 1486-1493, 2014

19 Gurme ST, "Evaluation of various factors affecting bioconversion of L-tyrosine to L-DOPA by yeast Yarrowia lipolytica-NCIM 3450 using response surface methodology" 4 : 141-147, 2014

20 이상원, "Establishment of a simple method for purification of high purity chlorogenic acid from immature fruit of pear (Pyrus pyrifolia Nakai)" 한국응용생명화학회 58 (58): 335-341, 2015

21 Xiao Y, "Enhancement of the antioxidant capacity of soy whey by fermentation with Lactobacillus plantarum B1–6" 12 : 33-44, 2015

22 Funayama M, "Effect of α-and β-arbutin on activity of tyrosinases from mushroom and mouse melanoma" 59 : 143-144, 1995

23 Upston JM, "Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis" 160 : 701-710, 2002

24 Boeing H, "Critical review:Vegetables and fruit in the prevention of chronic diseases" 51 : 637-663, 2012

25 이유건, "Coumaroyl Quinic Acid Derivatives and Flavonoids from Immature Pear (Pyrus pyrifolia Nakai) Fruit" 한국식품과학회 22 (22): 803-810, 2013

26 Dudonne S, "Comparative study of antioxidant properties and total phenolic content of 30 plant extracts of industrial interest using DPPH, ABTS, FRAP, SOD and ORAC assays" 57 : 1768-1774, 2009

27 Singleton VL, "Colorimetry of total phenolics with phospomolybdicphosphotungstic acid reagents" 16 : 144-158, 1965

28 Leitinger, N, "Cholesteryl ester oxidation products in atherosclerosis" 24 : 239-250, 2003

29 Lee, YG, "Change in flavonoid composition and antioxidative activity during fermentation of onion (Allium cepa L .) by Leuconostoc mesenteroides with different salt concentrations" 81 : C1385-C1393, 2016

30 Cho JY, "Change in chemical constituents and free radical-scavenging activity during pear (Pyrus pyrifolia) cultivar fruit development" 79 : 260-270, 2015

31 Cho JY, "Caffeoyl triterpenes from pear (Pyrus pyrifolia Nakai) fruit peels and their antioxidative activities against oxidation of rat blood plasma" 64 : 4563-4569, 2013

32 Wang YC, "Antioxidant activities of soy milk fermented with lactic acid bacteria and bifidobacteria" 23 : 128-135, 2006

33 Cushnie TP, "Antimicrobial activity of flavonoids" 26 : 343-356, 2005

34 조정용, "An Ether and Three Ester Derivatives of Phenylpropanoid from Pear (Pyrus pyrifolia Nakai cv. Chuhwangbae) Fruit and Their Radical-Scavenging Activity" 한국식품과학회 23 (23): 253-259, 2014

35 Seifried HE, "A review of the interaction among dietary antioxidants and reactive oxygen species" 11 : 567-579, 2007