실험조작에 의한 Heart Failure의 Guinea Pig 심근세포 미세구조의 변화 = Ultrastructural Changes in the Guinea Pig Myocardium in Experimental Heart Failure

다국어 초록 (Multilingual Abstract)

An ultrastructural study of Guinea Pig myocardium with established experimental left ventricular hypertrophy was undertaken to determine size and relative volume of myofibrils and mitochondria and to describe changes in the ultrastructure of them with this condition.
In the change in relative volume of myofibrils and mitochondria, left ventricular mitochondrial volume per fiber decreased after stenosis of ascending aorta. On the other hand, that of myofibrils increased with time.
Sarcomere after stenosis of ascending aorta showed decrease in length. on the other hand, there is a general trend of increasing in length of mitochondria. The ultrastructure changes in myofibrils found at fourth day an eighth day after were fraying, contraction band, altered Z-band and altered intercalated disc. The intensity of the changes was related to the length of time that the artery was narrowed.