융기성 피부섬유육종의 치료를 위한 광범위절제술과 모즈 미세도식 수술의 비교 연구: 단일 기관의 경험 = Study on the Comparison between Wide Excision and Mohs Micrographic Surgery for the Management of Dermatofibrosarcoma Protuberans: A Single Institution Experience융기성 피부섬유육종의 치료를 위한 광범위절제술과 모즈 미세도식 수술의 비교 연구: 단일 기관의 경험

다국어 초록 (Multilingual Abstract)

Background: Dermatofibrosarcoma protuberans is a mesenchymal tumor of the skin of intermediate-grade which is a rare condition. The slow growing and aggressive invasion on local tissues are characteristic features of dermatofibrosarcoma protuberans. The treatment for dermatofibrosarcoma protuberans is mainly a surgical excision such as a wide excision and Mohs micrographic surgery. Objective: The aim of this study was to compare the result of wide excision and Mohs micrographic surgery for the treatment of dermatofibrosarcoma protuberans at a single institution in Korea. Methods: A retrospective review was done for 24 patients diagnosed with dermatofibrosarcoma protuberans and treated surgically from 1999 to 2010 at Chonbuk National University Hospital. Patient demographics, tumor features, surgical features, and recurrence during the follow-up period were evaluated. Results: 13 patients were treated with wide excision, and 11 with Mohs micrographic surgery. There was no metastasis for all the cases. Mean operation time for the wide excision group was 83 minutes whereas 182 minutes for the Mohs micrographic surgery group, and it was a statistically significant difference. However, no significant difference was observed in post-operative defect size, advanced surgical repair and local recurrence in our study. Conclusion: We suggest that wide excision and Mohs micrographic surgery are both successful modalities for the surgical treatment of dermatofibrosarcoma protuberans. Hence, individualized patient and tumor characteristics should be concerned when determining the surgical options for dermatofibrosarcoma protuberans. (Korean J Dermatol 2013;51(1):13∼20)