기저질환이 없이 성인에서 발생한 무균성 피하 농양 = Aseptic Subcutaneous Abscesses without an Underlying Disease

다국어 초록 (Multilingual Abstract)

Aseptic subcutaneous abscesses are characterized by deep, round lesions histologically consisting of neutrophils, without evidence of microorganisms on culture. Although these are sometimes reported in healthy individuals, most are reported in patients with inflammatory bowel disease, including Crohn's disease and ulcerative colitis. A 79-year-old man without underlying disease presented with multiple skin-colored nodules and masses on his face and extremities 4 years ago. All of the microbiology studies for bacteria and fungi were negative and he did not respond to antibiotics. However, the lesions improved markedly after systemic prednisolone treatment. We diagnosed his lesions as aseptic subcutaneous abscesses. Further studies to evaluate inflammatory bowel disease were negative. Here, we report a case of multiple aseptic subcutaneous abscesses without an underlying disease. (Korean J Dermatol 2014;52(1):44∼47)

참고문헌 (Reference)

1 Hara H, "Subcutaneous abscesses in a patient with ulcerative colitis" 42 : 363-365, 2000

2 von Tirpitz C, "Simultaneous onset of pyoderma gangrenosum and bitemporal abscesses of the upper eyelids during a flare of ulcerative colitis" 4 : 98-100, 1998

3 Murata I, "Recurrent subcutaneous abscess of the sternal region in ulcerative colitis" 94 : 844-845, 1999

4 Johnson JL, "Pyoderma gangrenosum associated with an aseptic splenic abscess in a patient with neurofibromatosis" 2013

5 Li KJ, "Concomitant aseptic subcutaneous abscess and immunoglobulin m nephropathy-rare extraintestinal manifestations in ulcerative colitis" 51 : 401-405, 2006

6 Maeshima K, "Behcet’s disease complicated by multiple aseptic abscesses of the liver and spleen" 19 : 3165-3168, 2013

7 Andre M, "Aseptic systemic abscesses preceding diagnosis of Crohn’s disease by three years" 40 : 525-527, 1995

8 Kinjo F, "Aseptic subcutaneous abscess associated with ulcerative colitis" 18 : 1214-1215, 2003

9 Andre MF, "Aseptic abscesses: a study of 30 patients with or without inflammatory bowel disease and review of the literature" 86 : 145-161, 2007

10 Ito T, "A case of aseptic abscesses syndrome treated with corticosteroids and TNF-alpha blockade" 23 : 195-199, 2013