치료저항성 강박장애의 약물학적 치료 및 통합적 치료 모형의 제안 = Pharmacotherapy and the Proposal of the Integrative Therapy Model for Treatment Resistant Obsessive-Compulsive Disorder

다국어 초록 (Multilingual Abstract)

There have been considerable advances in our understanding of the neurobiology and the treatment of obsessive-compulsive disorder (OCD). However, it seems that many patients with OCD are not met with proper treatment, and even the patients who receive sufficient therapy the response rate is not high. This paper reviews the pharmacological treatments of OCD with
special focus on therapeutic options for treatment resistance cases. In treating a resistant case, the clinical characteristics including comorbid conditions of the patient should be reevaluated. Through until recently, there has been no standarized guideline to treat resistance cases and much is up to clinician’s preference, but thoughtful selection and combination of drugs with optimized
psychosocial approach may improve the response rate. We propose an integrative therapy model for treatment resistant OCD to emphasize the need for the expansion of treatment resources. Treatment resistant OCD deserves more clinical and socioeconomic attentions and needs further research for management.

목차 (Table of Contents)

• 서 론
• 강박장애의 약물학적 치료의 일반적 지침
• 강박장애의 일차선택 치료제
• 강박장애의 유지치료
• 강박장애의 치료반응과 관련된 요인
• 강박장애의 치료 저항성
• 치료저항성 강박장애의 약물학적 치료전략
• 강박장애의 통합적 치료모형
• 결 론
• REFERENCES