삼귀용탕(蔘歸茸湯)이 정상 흰쥐 및 Streptozotocin으로 유도된 당뇨병 흰쥐의 혈당에 대한 영향 = Effects of Samguiyong-tang on the Blood Glucose Levels in Normal Rats or Diabetic Rats Induced by Streptozotocin삼귀용탕(蔘歸茸湯)이 정상 흰쥐 및 Streptozotocin으로 유도된 당뇨병 흰쥐의 혈당에 대한 영향

다국어 초록 (Multilingual Abstract)

Objectives: In order to evaluate the effect of Samguiyong-tang (SGYT) on diabetes, we prepared two types of Samguiyong-tang (Type-Ⅰ and -Ⅱ) which was composed of three kinds of oriental drug such as Ginseng, Angelica gigantis radix and Deer antler. Type Ⅰ was traditional hot-water extract prepared from three kinds of drug, and Type Ⅱ was the mixture of ethanol-extract of ginseng and hot-water extract prepared from the other two drugs. Methods: We tested the effects of SGYT on the blood glucose levels in normal rats by the method of glucose tolerance test. And also examined the effects of SGYT on the levels in normal rats or diabetic rats induced by Streptozotocin during 20 days. Results: 1. In the course of oral glucose tolerance test, the blood glucose level decreased by administration of SGYT Ⅰ or Ⅱ in normal rats. 2. In the course administration of SGYT during 20 days in normal rats, the blood glucose levels decreased until day 4 by Type Ⅰ or Type Ⅱ, but thereafter the level was recovered to the normal. 3. In the course administration of SGYT during 20 days in the diabetic rats induced by streptozotocin, Type Ⅰ (SGYT) had some effect on the blood glucose levels only at 12 day, and Type Ⅱ (SGYT) decreased the levels from 6th day and so on, significantly. Conclusions: The results suggested that SGYT Ⅱ had some decreasing effects on the blood glucose levels in diabetic rats induced by Streptozotocin.