[P423] Two cases of unilateral linear syringoma on trunk following Blaschko lines = [P423] Two cases of unilateral linear syringoma on trunk following Blaschko lines

다국어 초록 (Multilingual Abstract)

Syringoma is a benign adnexal tumor arising from the ducts of eccrine sweat glands. They are flesh-colored or light brown small papules, localized most commonly on the lower eyelids and malar area. The lesions usually are bilateral and symmetrically distributed. We report two cases of unilateral linear syringoma following Blaschko`s line. We describe a 24-year-old male with mild itchy brownish papule on left upper flank of two years duration and 28-year-old female with a five-year history of asymptomatic brownish papules on left abdomen and flank. Histological examination showed multiple dilated eccrine ducts which were lined by two rows of epithelial cells. Some of the ducts had small comma-like tails of epithelial cells, giving them the appearance of tadpoles. The clinico-pathological features suggested the diagnosis of unilateral linear syringoma. Unilateral cases of syringoma following Blaschko`s lines are quite uncommon in the literature and have been reported to be localized on the extensor aspect of the right upper arm and the right chest. To our knowledge, this is the first case of unilateral linear syringoma on trunk following Blaschko`s lines. The development of syringoma following Blaschko`s lines suggests that a somatic mutation may underlie the pathogenesis of this dermatosis. Syringoma should be included in the differential diagnoses when we encounter linearly arranged skin lesions for the pathological examination.