RISS 검색 - 국내학술지논문 상세보기

부가정보

다국어 초록 (Multilingual Abstract)

In this study, ingredients were analyzed to see if ginseng flower extracts help suppress skin aging, and physiological activities were tested to evaluate antioxidant effects, cytotoxicity, anti-inflammatory effects, and cell regeneration effects. The GC/MS component analysis showed that the highest content was sucrose (18.72%) which is a polysaccharide used as a moisturizer, followed by Decanoic acid and 2- ethyl hexyl ester (10.01%), and the phenolic compound 2-Methoxy-4-vinyl phenol (3.69%). Antioxidant (DPPH) measurements also confirmed that when the control Vit.C shows 97% dissipation, ginseng flower extract increases in concentration from 0.25 mg/mL to 39.15±1.25%, 0.5 mg/mL to 49.44±0.99%, and 1 mg/mL to 71.91±5.67%. The cytotoxicity assessment showed that ginseng flower extracts were safe and not toxic material with a survival rate of 89.1±79.76% at 0.25 mg/mL, 86.8±84.08% at 0.5 mg/mL, and 85.48±79.56% at 1 mg/mL. In addition, ginseng flower extracts were found to have an anti-inflammatory effect as they concentratedependent inhibition of NO production at 24.41±6.30 μM at 0.25 mg/mL, 23.95±9.69 μM at 0.5 mg/mL, and 14.37±10.34 μM at 1 mg/ mL. According to the results of observing the cell migration rate by concentration (0.25%, 0.5%, 1%) of ginseng flower extracts with an Inverted microscope, the empty space of the scratch narrows as the concentration of the extract increases, and the cell proliferates actively, which shows that ginseng flower extracts promote skin regeneration. Through this experiment, ginseng flower extracts are safe without toxicity and have antioxidant activity, anti-inflammatory effect, and cell regeneration effectiveness of the skin, which has inhibitory skin aging. As a result, ginseng flower extracts will be used as natural cosmetics to help prevent skin aging, although more clinical experiments will be needed in the future, and research on various application methods will continue.