간흡충증의 임상상 = Clinical Features in Clocorchiasis간흡충증의 임상상

다국어 초록 (Multilingual Abstract)

N/A

다국어 초록 (Multilingual Abstract)

Background/Aims: Clonorchis sinensis, the Chinese liver fluke, is an important human parasite and is widely distributed in Southern Korea, China, Taiwan, Japan and Eastern Asia. Methods: To understand the more extensive clinical feature of clonorchiasis, we carried out an investigation retrospectively for hematology, blood biochemistry, clinical symptoms, and radiologic findings on a total of 309 clonorchiasis patients whose stools were positive for eggs of clonorchis sinensis at Chonbuk univeristy hospital. Results: 309 patients(270 males and 39 females) aged between 18 and 78 years. Common symptoms were right upper quadrant pain in 43 cases(13.9%), generalized weakness in 39 cases(12.6%), and jaundice in 39 cases(12.6%), and hepatomegaly in 25 cases(8%). 87 out of 250 cases(34.8%) showed normal eosinophilic count. The level of ALT was normal in 237 out of 303 cases(78.2%). The patients with more than 101 unit of ALT were 35 out of 303 cases(11.6%). In 131 patients among 275 cases, alkaline phosphatase value were in the normal limit(47.6%). As for ultrasonography, we couldnt find out abnormal findings in 62 out of 122 cases(51.8%). But 16 out of 122 cases(13.1%) showed the peripheral intrahepatic duct dilatation. And 14 cases(11.5%) showed the echoes of worms of clonorchiasis in the gall bladder. In 11 out of 46 cases(32.4%), abdominal CT showed diffuse dilatation of the periphera1 bile ducts. In 57 out of 81 patients(70.4%), there were positive reaction in intradermal test for clonorchis sinensis. And they had cross reaction with paragonimiasis in 23 out of 81 cases(28.4%). Conclusions: In the view of the results so far achieved, the result of our investigation is wide difference acompared with others report for clonorchiasis. We thought this difference is probably due to include more lightly infected persons by clonorchis sinensis in our .tudy group. So we suggest, to understand the clinical manifestation of clonorchiasis, it is necesssary to carry out examination for ultrasonography, abdominal CT and laboratory finding of patients depend on the number of worms, infection period, intensity and complication. (Korean J Gastroenterol 1995;27:64-71)