Prevalence of Irritable Bowel Syndrome in Singapore and Its Association with Dietary, Lifestyle, and Environmental Factors = Prevalence of Irritable Bowel Syndrome in Singapore and Its Association with Dietary, Lifestyle, and Environmental Factors

다국어 초록 (Multilingual Abstract)

Background/Aims The prevalence of irritable bowel syndrome (IBS) has risen considerably over the past decade in Singapore. We aim to explore the contribution of changes in diet, lifestyle and habits that may contribute to the increased prevalence and development of IBS. Methods This is a survey-based cross-sectional population study aimed to gather demographic, socio-economical, lifestyle, dietary, antibiotic usage and other related information. Subjects were adult male or female Singaporeans aged 21 years or above. Association of the factors gathered with the presence or absence of IBS (by Rome III criteria) was assessed using chi-square or Fisher’s exact test. Variables with a level of statistical significance of 0.1 or less in the univariate analysis were entered into a stepwise logistic regression model. Results A total of 297 subjects participated in the study (female 60.3%). Overall, 20.9% subjects fulfilled the Rome III IBS criteria. Univariate analysis showed that IBS was associated with pet ownership, antibiotic usage, late dinner, (> 9 PM) and consumption of Western meals, coffee, and bread. The multivariate logistic regression analyses showed that IBS was independently associated with being a pet owner (P = 0.008; OR, 2.5; 95% CI, 1.278-5.037). Conclusions The prevalence of IBS was 20.9% using the Rome III criteria in our study. The association between IBS and pet ownership will need further investigation.

참고문헌 (Reference)

1 Lee YY, "Whitehead WE. Rome III survey of irritable bowel syndrome among ethnic Malays" 18 : 6475-6480, 2012

2 Lee CG, "Visceral abdominal obesity is associated with an increased risk of irritable bowel syndrome" 110 : 310-319, 2015

3 Rossetti J, "Use of animal-assisted therapy with psychiatric patients" 48 : 44-48, 2010

4 Dunstan DW, "Too much sitting--a health hazard" 97 : 368-376, 2012

5 Gwee KA, "The prevalence, symptom characteristics, and impact of irritable bowel syndrome in an asian urban community" 99 : 924-931, 2004

6 Jones MP, "The overlap of atopy and functional gastrointestinal disorders among 23,471 patients in primary care" 40 : 382-391, 2014

7 Howell S, "The irritable bowel syndrome has origins in the childhood socioeconomic environment" 99 : 1572-1578, 2004

8 Hunskar GS, "The impact of atopic disease on the risk of post-infectious fatigue and irritable bowel syndrome 3 years after Giardia infection. A historic cohort study" 47 : 956-961, 2012

9 Sripanyakorn S, "The comparative absorption of silicon from different foods and food supplements" 102 : 825-834, 2009

10 Dong Won Park, "The Differences in Prevalence and Sociodemographic Characteristics of Irritable Bowel Syndrome According to Rome II and Rome III" 대한소화기 기능성질환∙운동학회 16 (16): 186-193, 2010

11 Saunders TJ, "Sedentary behaviour as an emerging risk factor for cardiometabolic diseases in children and youth" 38 : 53-61, 2014

12 Owen N, "Sedentary behaviour and health: mapping environmental and social contexts to underpin chronic disease prevention" 48 : 174-177, 2014

13 Drossman DA, "Rome III: New standard for functional gastrointestinal disorders" 15 : 237-241, 2006

14 Huerta C, "Risk of irritable bowel syndrome among asthma patients" 11 : 31-35, 2002

15 Yazar A, "Respiratory symptoms and pulmonary functional changes in patients with irritable bowel syndrome" 96 : 1511-1516, 2001

16 Deurenberg-Yap M, "Relationships between indices of obesity and its comorbidities in multi-ethnic Singapore" 25 : 1554-1562, 2001

17 Ozol D, "Relationship between asthma and irritable bowel syndrome: role of food allergy" 43 : 773-775, 2006

18 Beetz A, "Psychosocial and psychophysiological effects of human-animal interactions: the possible role of oxytocin" 3 : 234-, 2012

19 Solmaz M, "Psychological factors in the irritable bowel syndrome" 8 : 549-556, 2003

20 Mykletun A, "Prevalence of mood and anxiety disorder in self reported irritable bowel syndrome (IBS). An epidemiological population based study of women" 10 : 88-, 2010

21 Miwa H, "Prevalence of irritable bowel syndrome in Japan: internet survey using Rome III criteria" 2 : 143-147, 2008

22 Ho KY, "Prevalence of gastrointestinal symptoms in a multiracial Asian population, with particular reference to reflux-type symptoms" 93 : 1816-1822, 1998

23 Phatak UP, "Prevalence of functional gastrointestinal disorders in obese and overweight children" 38 : 1324-1327, 2014

24 Gwee KA, "Prevalence of disturbed bowel functions and its association with disturbed bladder and sexual functions in the male population" 27 : 1738-1744, 2012

25 Tremblay MS, "Physiological and health implications of a sedentary lifestyle" 35 : 725-740, 2010

26 Simpson A, "Pets and the development of allergic sensitization" 5 : 212-220, 2005

27 Pickett-Blakely O, "Obesity and irritable bowel syndrome: a comprehensive review" 10 : 411-416, 2014

28 Dempsey PC, "Managing sedentary behavior to reduce the risk of diabetes and cardiovascular disease" 14 : 522-, 2014

29 Kennedy TM, "Irritable bowel syndrome, gastro-oesophageal reflux, and bronchial hyper-responsiveness in the general population" 43 : 770-774, 1998

30 Lillestøl K, "Indications of ‘atopic bowel’ in patients with self-reported food hypersensitivity" 31 : 1112-1122, 2010

31 Roussos A, "Increased prevalence of irritable bowel syndrome in patients with bronchial asthma" 97 : 75-79, 2003

32 Powell N, "Increased prevalence of gastrointestinal symptoms in patients with allergic disease" 83 : 182-186, 2007

33 Cole JA, "Incidence of IBS in a cohort of people with asthma" 52 : 329-335, 2007

34 Kindt S, "Immune dysfunction in patients with functional gastrointestinal disorders" 21 : 389-398, 2009

35 Koloski NA, "Identification of early environmental risk factors for irritable bowel syndrome and dyspepsia" 27 : 1317-1325, 2015

36 Grandgeorge M, "Human-animal relationships: from daily life to animal-assisted therapies" 47 : 397-408, 2011

37 Morris DO, "Human allergy to environmental pet danders: a public health perspective" 21 : 441-449, 2010

38 Olden K, "Health-related disparities: influence of environmental factors" 89 : 721-738, 2005

39 Le Pluart D, "Functional gastrointestinal disorders in 35,447 adults and their association with body mass index" 41 : 758-767, 2015

40 Bouchoucha M, "Functional Gastrointestinal Disorders in Obese Patients. The Importance of the Enrollment Source" 25 : 2143-2152, 2015

41 Takkouche B, "Exposure to furry pets and the risk of asthma and allergic rhinitis: a metaanalysis" 63 : 857-864, 2008

42 Rappaport SM, "Epidemiology. Environment and disease risks" 330 : 460-461, 2010

43 Gwee KA, "Epidemiology of irritable bowel syndrome in Asia: something old, something new, something borrowed" 24 : 1601-1607, 2009

44 Chitkara DK, "Early life risk factors that contribute to irritable bowel syndrome in adults: a systematic review" 103 : 765-774, 2008

45 Magnusson J, "Dahlman-Höglund A, et al. Seasonal intestinal inflammation in patients with birch pollen allergy" 112 : 45-50, 2003

46 Lu CL, "Current patterns of irritable bowel syndrome in Taiwan: the Rome II questionnaire on a Chinese population" 18 : 1159-1169, 2003

47 Amra B, "Correlation between asthma and irritable bowel syndrome in a general population in Iran in 2003" 100 : 110-114, 2006

48 Vivinus-Nebot M, "Combination of allergic factors can worsen diarrheic irritable bowel syndrome: role of barrier defects and mast cells" 107 : 75-81, 2012

49 Tobin MC, "Atopic irritable bowel syndrome: a novel subgroup of irritable bowel syndrome with allergic manifestations" 100 : 49-53, 2008

50 Panicker R, "Association and symptom characteristics of irritable bowel syndrome among bronchial asthma patients in Kuwait" 5 : 37-42, 2010

51 WHO Expert Consultation, "Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies" 363 : 157-163, 2004

52 Muñoz Lasa S, "Animal-assisted interventions in internal and rehabilitation medicine: a review of the recent literature" 53 : 129-136, 2011

53 Cirulli F, "Animal-assisted interventions as innovative tools for mental health" 47 : 341-348, 2011