전이성 뇌실질내 종양환자의 예후에 영향을 미치는 인자들

다국어 초록 (Multilingual Abstract)

This study was conducted on 60 metastatic brain parenchymal tumor patients admitted at this hospital between January of 1987 and July of 1993. The mean age of the patients was 54, the youngest to be 26 and the oldest, 78. The ratio of male v.s. female was 1:2.3, 50 were single metastatic and 10 were multiple.
The following are the results of the analyses of the factors affecting the prognoses of metastatic brain parenchymal tumor patients: The group operated on showed a significantly prolonged life-span as compared with the one without operation, which was also phenomenal among the single metastatic patients. Among the primary tumors, breast cancer had the longest median survival period, 20 months, and the shortest one was with the gasrointestinal, one month. As for clinical grade and survival span, those above Karnofsky scale of 80 survived a median of six months, and those below 50 survived for 2 months. The group with favorable clinical conditions before operation resulted in significantly long life span. Especially in the group with 80 above of Karnosky scale, the operated group showed a far excellent prognoses as against the non operated. The median survival time was 20 months in the group with more than 12 months as an interval between diagnoses of primary tumor and metastasis, wherease it was 3 months for the group with the interval less than 6 months. Thus, the longer the interval, the better the prognosis was. This fact was significant statistically. Among the patients with interval of 12 months or more, the operated group also showed better prognosis than the nonoperated. The mean six months survial rate was 33.3%, one-year rate was 23.3%, two-year rate was 10.0% in all the cases. The longest survival time was 36 months.The whole body metastasis was the most common cause of death, accounting for 64.2%.

목차 (Table of Contents)

• 목차
• 서론 = 1
• 대상 및 방법 = 2
• 결과 = 3
• 1. 대상환자들의 임상분석 = 3
• 2. 연령에 따른 생존기간 = 3
• 3. 치료방법에 따른 생존기간 = 4
• 4. 원발종양 부위에 따른 생존기간 = 4
• 5. 뇌실질 전이종양 부위에 따른 생존기간 = 4
• 6. 뇌실질 전이 진단 당시 임상정도와 생존기간 = 5
• 7. 원발종양의 진단에서 뇌실질내 진단까지의 기간에 따른 생존율 = 5
• 8. 전체환자의 뇌실질내 전이 진단후 생존기간에 따른 생존율과 사망원인 = 5
• 고찰 = 15
• 뇌전이종양의 빈도 = 15
• 생존기간 = 16
• 예후에 영향을 미치는 인자 = 17
• 결론 = 19
• References = 20
• Abstract = i