폐결핵치료 중인 환자에서 Rifampicin에 의해 유발된 위막성 대장염 2예 = Two Cases of Rifampicin Induced Pseudomembranous Colitis in Patients Who Underwent Anti-Tuberculosis Therapy

다국어 초록 (Multilingual Abstract)

Pseudomembranous colitis (PMC) is a disease caused by Clostridium difficile proliferation. The causative drugs are clindamycin, third-generation cephalosporins, flouroquinolone and so on. Rifampicin has been reported as a cause of PMC in the 1980s, and the frequency of PMC is increasing because rifampicin is a first line drug for anti-tuberculosis therapy. Two patients were recently admitted to our hospital due to watery diarrhea for 1 month and they were diagnosed with PMC by sigmoidoscopy. Their onset age were 74, 72 years old and latent period of symptoms were 60, 129 days, respectively. In one case, the patient displayed coexisting hypertension and diabetes. The clinical symptoms improved after discontinuing the rifampicin and then administering oral metronidazole. We report here on two cases presumed to be rifampicin-induced PMC.

목차 (Table of Contents)

• 서론
• 증례1
• 증례2
• 고찰
• 참고문헌

참고문헌 (Reference)

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