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      KCI등재 SCOPUS

      Use of Parathyroid Hormone and Rehabilitation Reduces Subsequent Vertebral Body Fractures after Balloon Kyphoplasty

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      https://www.riss.kr/link?id=A108504301

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      다국어 초록 (Multilingual Abstract)

      Study Design: Retrospective cohort study.Purpose: To evaluate the efficacy of our current prophylactic strategy by investigating the incidence of subsequent vertebral body fractures (SVBFs) following balloon kyphoplasty (BKP).Overview of Literature: A...

      Study Design: Retrospective cohort study.Purpose: To evaluate the efficacy of our current prophylactic strategy by investigating the incidence of subsequent vertebral body fractures (SVBFs) following balloon kyphoplasty (BKP).Overview of Literature: Although extensive studies have investigated the risk factors for SVBFs after BKP, few have reported on postoperative therapies to prevent SVBFs and have evaluated their effectiveness.Methods: This study enrolled 273 patients who underwent an initial BKP. To treat osteoporosis, parathyroid hormone (PTH) administration was started 1–2 weeks before BKP and continued for at least 6 months postoperatively. Corsets were applied for 3 months after the procedure. Rehabilitative interventions, including hip range-of-motion training, muscle strengthening exercises, and motion/posture instruction, were started from the preoperative assessment time point and resumed 3 hours postoperatively. Corsets were used in all patients. Therefore, no grouping based on corset use was performed. PTH was used in 180 patients, and they were divided into the following two groups: PTH user group and PTH nonuser group. Rehabilitative interventions were provided to all patients for a median duration of 17 days. Patients who underwent rehabilitative intervention for <17 and ≥17 days were included in the short-term and long-term intervention groups, respectively. The incidences of SVBFs for these four groups were compared.Results: SVBF occurred in 29 patients (10.6%). The SVBF incidence among patients who were prescribed all three prophylactic measures was 6.2%. The PTH user group had a significantly lower incidence of distant vertebral body fractures as compared to the PTH nonuser group. The long-term rehabilitation group had a significantly lower incidence of SVBFs and adjacent vertebral body fractures within 50 postoperative days than the short-term group.Conclusions: A 17-day or longer rehabilitative intervention may lower the risk of early adjacent vertebral body fractures, and the use of PTH may reduce the risk of distant vertebral body fractures.

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      참고문헌 (Reference) 논문관계도

      1 Akabane Y, "Therapeutic exercise for osteoporotic spinal compression fractures : vertebral body compression deformity inhibitory effect" 44 : 527-533, 2010

      2 Nakayama Y, "The surgical outcome of balloon kyphoplasty(BKP) : minimum 2years follow-up" 7 : 1727-1730, 2016

      3 Nachemson AL, "The lumbar spine : an orthopaedic challenge" 1 : 59-71, 1976

      4 Sano S, "The evaluation of new vertebral fracture after balloon kyphoplasty" 6 : 1076-1082, 2015

      5 Usui M, "The effect of the throraco-lumbar orthosis on the mobility of the thoracolumbar junction : Damen corset, Jewett brace and cast" 39 : 116-119, 2014

      6 Sinaki M, "Stronger back muscles reduce the incidence of vertebral fractures : a prospective 10 year follow-up of postmenopausal women" 30 : 836-841, 2002

      7 Hirose T, "Strategies to prevent subsequent vertebral body fractures after balloon kyphoplasty : evaluation of the effect of teriparatide" 65 : 833-836, 2016

      8 Omi H, "Risk factors of early adjacent vertebral fracture after balloon kyphoplasty" 5 : 930-933, 2014

      9 Oishi Y, "Risk factors for the early subsequent adjacent vertebral fractures after balloon kyphoplasty" 4 : 1789-1792, 2013

      10 Farrokhi MR, "Randomized controlled trial of percutaneous vertebroplasty versus optimal medical management for the relief of pain and disability in acute osteoporotic vertebral compression fractures" 14 : 561-569, 2011

      1 Akabane Y, "Therapeutic exercise for osteoporotic spinal compression fractures : vertebral body compression deformity inhibitory effect" 44 : 527-533, 2010

      2 Nakayama Y, "The surgical outcome of balloon kyphoplasty(BKP) : minimum 2years follow-up" 7 : 1727-1730, 2016

      3 Nachemson AL, "The lumbar spine : an orthopaedic challenge" 1 : 59-71, 1976

      4 Sano S, "The evaluation of new vertebral fracture after balloon kyphoplasty" 6 : 1076-1082, 2015

      5 Usui M, "The effect of the throraco-lumbar orthosis on the mobility of the thoracolumbar junction : Damen corset, Jewett brace and cast" 39 : 116-119, 2014

      6 Sinaki M, "Stronger back muscles reduce the incidence of vertebral fractures : a prospective 10 year follow-up of postmenopausal women" 30 : 836-841, 2002

      7 Hirose T, "Strategies to prevent subsequent vertebral body fractures after balloon kyphoplasty : evaluation of the effect of teriparatide" 65 : 833-836, 2016

      8 Omi H, "Risk factors of early adjacent vertebral fracture after balloon kyphoplasty" 5 : 930-933, 2014

      9 Oishi Y, "Risk factors for the early subsequent adjacent vertebral fractures after balloon kyphoplasty" 4 : 1789-1792, 2013

      10 Farrokhi MR, "Randomized controlled trial of percutaneous vertebroplasty versus optimal medical management for the relief of pain and disability in acute osteoporotic vertebral compression fractures" 14 : 561-569, 2011

      11 Isomi T, "QOL scale and standing sagittal plane alignment of the thoracolumbar kyphosis in patients with osteoporotic vertebral fractures, and the effect of therapeutic exercise" 15 : 583-590, 2007

      12 Pflugmacher R, "Incidence of adjacent vertebral fractures in patients treated with balloon kyphoplasty : two years’ prospective follow-up" 47 : 830-840, 2006

      13 Committee for the Development of Guidelines for Prevention and Treatment of Osteoporosis, "Guidelines for prevention and treatment of osteoporosis" Life Science Publishing 116-, 2015

      14 Ueno M, "Efficacy of weekly teriparatide for secondary vertebral compression fracture following balloon kyphoplasty" 4 : 1399-1404, 2013

      15 Bouza C, "Efficacy and safety of balloon kyphoplasty in the treatment of vertebral compression fractures : a systematic review" 15 : 1050-1067, 2006

      16 Kelley GA, "Effects of ground and joint reaction force exercise on lumbar spine and femoral neck bone mineral density in postmenopausal women : a meta-analysis of randomized controlled trials" 13 : 177-, 2012

      17 Yasuoka H, "Effect of daily teriparatide dosage following BKP(balloon kyphoplasty)method : can it prevent new vertebral body fractures after BKP?" 27 : 116-117, 2014

      18 Wilson DR, "Effect of augmentation on the mechanics of vertebral wedge fractures" 25 : 158-165, 2000

      19 Sawada T, "Bone mineral density based study of early vertebral fracture after balloon kyphoplasty" 8 : 1164-1166, 2017

      20 Voggenreiter G, "Balloon kyphoplasty is effective in deformity correction of osteoporotic vertebral compression fractures" 30 : 2806-2812, 2005

      21 Taylor RS, "Balloon kyphoplasty in the management of vertebral compression fractures : an updated systematic review and meta-analysis" 16 : 1085-1100, 2007

      22 Friedrich HC, "Balloon kyphoplasty improves back pain but does not result in a permanent realignment of the thoracolumbar spine" 72 : 176-180, 2011

      23 Garfin SR, "Balloon kyphoplasty for symptomatic vertebral body compression fractures results in rapid, significant, and sustained improvements in back pain, function, and quality of life for elderly patients" 31 : 2213-2220, 2006

      24 BelkoffSM, "An ex vivo biomechanical evaluation of an inflatable bone tamp used in the treatment of compression fracture" 26 : 151-156, 2001

      25 Kayanja MM, "Adjacent level load transfer following vertebral augmentation in the cadaveric spine" 31 : E790-7, 2006

      26 Kong M, "12-Month teriparatide treatment reduces new vertebral compression fractures incidence and back pain and improves quality of life after percutaneous kyphoplasty in osteoporotic women" 14 : 1693-1703, 2019

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