Objective : To investigate the pathogenesis of anemia and serum protein alteration in patient with pressure ulcer and proper management method.
Method : Eleven patients with pressure ulcer were investigated. To investigate the change of anemia and se...
Objective : To investigate the pathogenesis of anemia and serum protein alteration in patient with pressure ulcer and proper management method.
Method : Eleven patients with pressure ulcer were investigated. To investigate the change of anemia and serum protein between pre- and post-treatment of pressure ulcer, we measured hemoglobin, hematocrit, serum iron, ferritin, transferrin, mean corpuscular volume(MCV), red cell count, serum albumin and globulin before and after healing of pressure ulcer.
Result : There was significant increases of hemoglobin, hematocrit, red cell count, MCV, serum iron, ferrtin and transferrin after healing of pressure ulcer(p<0.05). The serum ablumin and A/G ratio were increased significantly(p<0.05). The total globulin and α1-globulin were decreased significantly(p<0.05). There was no statically significant relationship between the ulcer size and the degree of anemia and hypoalbuminemia.
Conclusion : This research suggested that anemia and serum protein alteration in patient with pressure ulcer are thought result from chronic inflammatory process. So, anemia and alteration of protein does not require any treatment such as transfusion, iron and albumin supply.