기허가 한약제제를 대상으로 한 인지장애 치료 유효 약물 탐색 - 인지장애 임상연구를 위한 예비연구

목차 (Table of Contents)

• 서론
• 재료 및 방법
• 결과
• 고찰
• 결론
• References

참고문헌 (Reference)

1 지은혜, "황련해독탕제제의 지표성분 동시 분석을 통한 품질비교" 한국생약학회 41 (41): 161-165, 2010

2 김예지, "황련해독탕 전탕액과 시판제제의 성분 및 효능 비교" 한국생약학회 44 (44): 22-29, 2013

3 김우영, "한의학의 치매관련 임상연구 동향분석과 제안" 한국한의학연구원 17 (17): 39-46, 2011

4 조희근, "한약처방을 사용한 치매에 대한 실험연구 동향분석－국내 학위논문을 중심으로－" 한방재활의학과학회 24 (24): 29-40, 2014

5 이형철, "한약재 물 추출물의 아세틸콜린에스테라제 활성 억제 검색" 한의병리학회 16 (16): 2-219, 2002

6 이형철, "한약재 물 추출물의 Monoamine Oxidase B의 활성 억제 및 항산화 활성 검색" 한의병리학회 16 (16): 7-463, 2002

7 권용주, "치매의 한약물 치료에 대한 체계적 임상논문 고찰 - 국내문헌을 중심으로 -" 대한한방신경정신과학회 21 (21): 151-161, 2010

8 서영경, "치매, 경도인지장애의 한의진료 현황, 진단 및 치료에 대한 한의사의 인식도 조사 연구 - 한방신경정신과 전문의와 일반의의 차이를 중심으로 -" 대한한방신경정신과학회 28 (28): 263-274, 2017

9 허은정, "치매 치료용 한약 처방의 연구성과에 대한 정성평가" 대한한방신경정신과학회 23 (23): 93-113, 2012

10 류병호, "초석잠 메탄올 추출물의 Acetylcholine Esterase 및 Monoamine Oxidase 활성 억제 효과" 한국식품영양학회 17 (17): 347-355, 2004

11 한설희, "알츠하이머병의 새로운 약물치료" 대한의사협회 52 (52): 1059-1068, 2009

12 김동렬, "시판 갈근탕의 항산화능의 비교" 한국식품영양과학회 32 (32): 728-732, 2003

13 김온순, "삼출건비탕 전탕액과 시판 한약제제의 비교 연구" 대한한의학방제학회 20 (20): 1-11, 2012

14 임혜선, "다빈도 한약 처방 50종의 아세틸콜린 분해 효소 활성 및 아밀로이드 베타 단백질 응집 억제 효능 비교 연구" 한국생약학회 47 (47): 287-294, 2016

15 임혜선, "국민 건강보험 급여 한약 처방 56종의 치매 주요 생리지표 및 신경세포 변화에 대한 효능 비교 연구" 대한한의학회 39 (39): 1-16, 2018

16 Lee SI, "Studies on the research and development of new dosage form of oriental medicine - Studies on preparation and evaluation of Lonicerae Caulis tablet" Korea Institute of Oriental Medicine 42-95, 1998

17 Ministry of Health and Welfare central dementia center, "Status of dementia in Korea"

18 Oh MH, "Screening of Korean herbal medicines used to improve cognitive function for anti-cholinesterase activity" 11 (11): 544-548, 2004

19 Liu B, "Role of microglia in inflammation-mediated neurodegenerative diseases : mechanisms and strategies for therapeutic intervention" 304 : 1-7, 2003

20 Minako H, "Regulation of mitochondrial pyruvate dehydrogenase activity by tau protein kinase I/glycogen synthase kinase 3β in brain" 93 : 2719-2723, 1996

21 Prince M, "Recent global trends in the prevalence and incidence of dementia, and survival with dementia" 8 (8): 23-, 2016

22 Wang X, "Pharmacokinetics of berberine in rat thalamus after intravenous administration of Coptidis rhizoma extract" 33 : 935-943, 2005

23 Ames BN, "Oxidants, antioxidants, and the degenerative diseases of aging" 90 : 7915-7922, 1993

24 The Korean Society of Oriental Neuropsychiatry Textbook Compilation Committee, "Oriental Neuropsychiatry" Jipmoondang 2016

25 Limón ID, "Neuroprotective effect of alpha-asarone on spatial memory and nitric oxide levels in rats injected with amyloid-beta" 453 (453): 98-103, 2009

26 Cavalli A, "Multi-target-directed ligands to combat neurodegenerative diseases" 51 : 347-372, 2008

27 Jia Yao, "Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease" 106 (106): 14670-14675, 2009

28 Petersen RC, "Mild Cognitive Impairment-Clinical Characterization and Outcome" 56 (56): 303-308, 1999

29 Zhao HF, "Long-term ginsenoside administration prevents memory loss in aged female C57BL/6J mice by modulating the redox status and up-regulating the plasticity-related proteins in hippocampus" 201 (201): 311-317, 2009

30 Central dementia center of Ministry of Health and Welfare, "Korean Dementia Observatory"

31 Cui Y, "Intelligence enhancement of radix Rehmanniae praeparata and some comments on its research" 27 : 404-406, 2002

32 The Textbook Compilation Committee of Herbalogy of Oriental Medical Schools in Nation, "Herbalogy" Younglim Publisher 2016

33 Kim HG, "Herbal medicines for the prevention and treatment of Alzheimer's diseases" 18 (18): 57-75, 2012

34 Korea Pharmaceutical Association, "Herbal medicine KGMP training" Seoul Corporation Korea Pharmaceutical Association 1996

35 Zhang H, "Effects of tenuifolin extracted from radix polygalae on learning and memory : a behavioral and biochemical study on aged and amnesic mice" 15 (15): 587-594, 2008

36 Yun S, "Effects of Cyperus rotundus (CPRT) on inhibition of impairment of learning and memory, and acetylcholinesterase in amnesia mice" 14 (14): 59-74, 2003

37 Lee DU, "Effects of 13-alkyl-substituted berberine alkaloids on the expression of COX-II, TNF-alpha, iNOS, and IL-12 production in LPS-stimulated macrophages" 73 : 1401-1412, 2003

38 Raina P, "Effectiveness of cholinesterase inhibitors and memantine for treating dementia : evidence review for a clinical practice guideline" 148 (148): 379-397, 2008

39 Chen W, "Effect of water extract of Poria on cytosolic free calcium concentration in brain nerve cells of neonatal rats" 18 (18): 293-295, 1998

40 Cui Y, "Effect of radix Rehmanniae preparata on the expression of c-fosand NGF in hippocampi and learning and memory in rats with damaged thalamic arcuate nucleus" 27 : 589-592, 2004

41 Burns A, "Dementia" 338 : b75-, 2009

42 Shin MK, "Clinical Herbalogy" Younglim Publisher 2000

43 Uday Saxena, "Bioenergetics breakdown in Alzheimer's disease : targets for new therapies" 3 (3): 133-139, 2011

44 "Article 2 (6) of the pharmaceutical affairs law"

45 Jung MH, "Analysis of trends in dementia medical care" 12 (12): 78-85, 2018

46 R Katzman, "Advances in Alzheimer's disease" 5 (5): 278-286, 1991