Through the Bucherer-Bergs method, new 5-alkylthio (sulfonyl)-methyl-p-x-phenylhydantoins were prepared. Hydantoin-3-acetates were synthesized by the reaction of the hydantoins and ethyl chloroacetate and through the subsequent hydrolysis of the 3-ace...
Through the Bucherer-Bergs method, new 5-alkylthio (sulfonyl)-methyl-p-x-phenylhydantoins were prepared. Hydantoin-3-acetates were synthesized by the reaction of the hydantoins and ethyl chloroacetate and through the subsequent hydrolysis of the 3-acetates with dilute sodium hydroxide hydantoin-3-acetic acids were obtained. These products are expected to exhibit antiinflammatory and analgetic activities.