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DBpiaThis study was done to determine the toxic effect of fthalide in rats which have oral administration at levels of 100 mg/kg/day for twelve days. It was examined the hematogram and serological parameters, and also the content of cytochrome P-450, the a...
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https://www.riss.kr/link?id=A45023248
- 저자
- 발행기관
- 학술지명
- 권호사항
-
발행연도
1993
-
작성언어
Korean
-
KDC
539.905
-
등재정보
SCOPUS,KCI등재
-
자료형태
학술저널
- 발행기관 URL
-
수록면
1-10(10쪽)
- 제공처
-
0
상세조회 -
0
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인용문이 복사되었습니다.
부가정보
다국어 초록 (Multilingual Abstract)
This study was done to determine the toxic effect of fthalide in rats which have oral administration at levels of 100 mg/kg/day for twelve days. It was examined the hematogram and serological parameters, and also the content of cytochrome P-450, the activity of NADPH-cytochrome c reductase, glucose-6-phosphatase, cholinesterase and carboxylesterase in liver.
Any significant alteration of hematogram was not found but the value of AST, LDH and content of glucose in serum were statistically increased.
The content of cytochrome P-450, the activty of NADPH-cytochrome c reductase were increased but glucose-6-phosphatase were slightly decreased compare with that of control group.
The activity of cholinesterase was decreased slightly and on the contrary the activity of carboxylesterase was found to be the tendeny of increase in both of liver and serum.
Any significant alteration of hematogram was not found but the value of AST, LDH and content of glucose in serum were statistically increased.
The content of cytochrome P-450, the activty of NADPH-cytochrome c reductase were increased but glucose-6-phosphatase were slightly decreased compare with that of control group.
The activity of cholinesterase was decreased slightly and on the contrary the activity of carboxylesterase was found to be the tendeny of increase in both of liver and serum.
This study was done to determine the toxic effect of fthalide in rats which have oral administration at levels of 100 mg/kg/day for twelve days. It was examined the hematogram and serological parameters, and also the content of cytochrome P-450, the activity of NADPH-cytochrome c reductase, glucose-6-phosphatase, cholinesterase and carboxylesterase in liver.
Any significant alteration of hematogram was not found but the value of AST, LDH and content of glucose in serum were statistically increased.
The content of cytochrome P-450, the activty of NADPH-cytochrome c reductase were increased but glucose-6-phosphatase were slightly decreased compare with that of control group.
The activity of cholinesterase was decreased slightly and on the contrary the activity of carboxylesterase was found to be the tendeny of increase in both of liver and serum.
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