여성에서 경도 간기능 이상과 비만과의 관련성 = Correlation between liver function and obesity in women

다국어 초록 (Multilingual Abstract)

Objective : This study investigated any correlation between obesity and mild abnormality of liver function. This investigation would support the necessity of the early management of obese people through detection of liver abnormality from a regular health check.
Methods and Materials : This study included a total of 748 female subjects age 20 to 70 years who have less than two times the standard liver function level. Measurements on Body Mass Index. Alcohol, HbsAg, HbsAb, High density lipoprotein (HDL), Triglyceride(TG), Total cholesterol(TC) in relation to the liver function-Aspartate Aminotransferase(AST), Alanine Aminotransferase(ALT), and -Glutamyl Transferase-were evaluated for both normal liver function group and mild abnormal liver function group(higher than the standard level but lower than two times the standard level).
Results : Using the logistic regression analysis, the odds ratio to the mild abnormality of liver function was that ALT with HbsAg was 5.9 fold, BMI level higher than 25㎏/㎡ was 2.17, TC level higher than 200㎎/dL was 2.14, and ALT with BMI higher than 25㎏/㎡ was 3.59. GTP with TC and TG higher than 200㎎/dL were 3.76 and 3.04 respectively.
Conclusion : It is found that there is a positive correlation between obesity and mild abnormality of liver function in female population. When mild abnormality of liver function is detected in female population, obesity and fat level in blood should be closely observed to prevent and to manage liver disease in female population.