A case of lymphangioma-like Kaposi sarcoma = A case of lymphangioma-like Kaposi sarcoma

다국어 초록 (Multilingual Abstract)

Lymphangioma-like kaposi sarcoma (LLKS) is a rare histologic variant of kaposi sarcoma that can present as any of the 4 known clinical variants. LLKS is a vascular neoplasm that develops secondary to infection by human herpesvirus type 8 (HHV-8), which is also known as the kaposi sarcoma virus. Clinically, it can present with the usual manifestations, namely, patches, plaques, or nodules. A 85-year-old female presented with painful plaque on the both sole that first appeared 1 month ago. She reported the lesions had gradually increased in number and size. Physical examination revealed raised erythematous, oval plaques measuring 1 cm in diameter. She had hypertension and otherwise healthy. Skin biopsy from the right sole demonstrated an atypical vascular proliferation of spindle cells interanastamosing as lymphangioma-like pattern. Immunohistochemical evaluation showed that tumor proliferation was positive for the endothelial markers such as CD31 and CD34. A Genotyping by PCR confirmed HHV-8 infection. After diagnosed with LLKS the patient was referred to the plastic surgery department for surgical excision. We herein report a rare case of lymphangioma like kaposi sarcoma.