급성 중증 유기인계 중독 환자의 예후 판정을 위한 Scoring Methods = Scoring Methods for Prognosis of Patients with Acute Severe Organophosphate Intoxication

다국어 초록 (Multilingual Abstract)

Purpose: Although, there have been many reports about
factors involved in the severity and prognosis of
organophosphate toxicity, there are few reports on integrated
application of scoring methods using those factors for
prognosis. Our report is about the possible application of
such scoring methods in the early stage of organophosphate
intoxication.
Methods: This study included organophosphate intoxication
patients who were admitted to the Emergency department
(ED) between March 1, 2004 and February 28, 2008.
We limited enrolment in the study to patients who had
required assisted mechanical ventilation and used atropine
for therapy. This was a retrospective study about age, drug
toxicity, mental status, existence of metabolic acidosis and
QT prolongation for each patient.
Results: Thirty seven patients were enrolled in this study.
Among the 37, 22 survived and 15 died. For survivors, drug
toxicity and mental status were correlated with total dose of
atropine, and the existence of metabolic acidosis was correlated
with the duration of mechanical ventilation. Survivors
had lower total scores than non-survivors.
Conclusion: Application of scoring methods that include
five factors (age, drug toxicity, mental status, existence of
metabolic acidosis, existence of QTc prolongation) when
acute, severe, organophosphate poisoning patients arrive
at an ED can be helpful for their prognosis.

참고문헌 (Reference)

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