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Park, Subin,Lee, Yeeun,Jun, Jin Yong Elsevier/North Holland Biomedical Press 2017 Psychiatry research Vol.257 No.-
<P><B>Abstract</B></P> <P>North Korean adolescent defectors experience adaptation difficulties along with a wide range of psychosocial problems, but no study has yet examined their Internet addiction symptoms. We compared early traumatic experiences, self-esteem, negative cognition, and Internet addiction symptoms, as well as the relationships between these variables, between North Korean adolescent defectors and South Korean adolescents. Fifty-six North Korean adolescent defectors and 112 age- and sex- matched South Korean adolescents participated. The analyses examined the relationship between traumatic experiences and Internet addiction symptoms, with negative automatic thoughts or low self-esteem as mediators of these relations. North Korean adolescent defectors tended to have higher levels of negative automatic thoughts and more severe Internet addiction symptoms, as well as better self-esteem, than did South Korean adolescents. Furthermore, only among North Korean adolescent defectors, traumatic experiences were positively associated with Internet addition symptoms via increasing negative automatic thoughts. North Korean adolescent defectors are more susceptible to Internet addiction, negative cognitions, and early traumatic experiences compared to South Korean adolescents. However, the cross-sectional design of this study precludes consideration of the causality of these relationships. Interventions aiming to correct negative cognitions and increase self-esteem may be helpful for North Korean adolescent defectors with problematic Internet use.</P> <P><B>Highlights</B></P> <P> <UL> <LI> North Korean adolescent defectors had higher trauma and Internet addiction (IA). </LI> <LI> North Korean defectors also had greater self-esteem and negative automatic thoughts. </LI> <LI> Self-esteem and negative thoughts were mediators in the relation of trauma and IA. </LI> <LI> Country of origin (North vs. South Korea) moderated the mediating effects. </LI> </UL> </P>
Cai, M.,Phan, P.T.T.,Hong, J.G.,Kim, D.H.,Kim, J.M.,Park, S.J.,Liu, X.,Han, J.E.,Park, H.,Choi, J.W.,Ryu, J.H. North-Holland ; Elsevier Science Ltd 2012 european journal of pharmacology Vol.689 No.1
Eupatilin, a pharmacologically active flavone derived from the Artemisia plant species, has been reported to have anti-oxidant, anti-inflammatory, anti-allergic, and anti-tumor activities. In the present study, we investigated whether eupatilin exhibits neuroprotective activities against ischemia/reperfusion-induced delayed neuronal injury in mice. Transient global cerebral ischemia was induced in mice by bilateral common carotid artery occlusion (BCCAO) for 15min followed by reperfusion for 4 days. Eupatilin (1, 3, or 10mg/kg, p.o.) was administered immediately after the reperfusion. Histochemical studies showed that eupatilin (10mg/kg) increased the number of viable cells detected by Nissl staining and decreased the number of degenerating neuronal cells detected by Fluoro-Jade B staining in the hippocampal CA1 region. Western blotting indicated that eupatilin further increased the level of Akt phosphorylation at 8h after BCCAO. Furthermore, wortmannin, a phosphatidylinositol 3-kinase inhibitor, attenuated the eupatilin-induced increase of Akt phosphorylation. In addition, wortmannin completely reversed the eupatilin-induced neuroprotective effects observed at 4 days after reperfusion. These findings suggest that eupatilin is a promising therapeutic agent against global cerebral ischemia-induced neuronal damage and that its neuroprotective effects may be mediated in part by increased Akt phosphorylation.
Stability of an implicit method to evaluate option prices under local volatility with jumps
Lee, J.,Lee, Y. North-Holland ; Elsevier Science Ltd 2015 Applied numerical mathematics Vol.87 No.-
In this paper, we consider a local volatility model with jumps under which the price of a European option can be derived by a partial integro-differential equation (PIDE) with nonconstant coefficients. In order to solve numerically the PIDE, we generalize the implicit method with three time levels which is constructed to avoid iteration at each time step. We show that the implicit method has the stability with respect to the discrete @?<SUP>2</SUP>-norm by using an energy method. We combine the implicit method with an operator splitting method to solve a linear complementarity problem (LCP) with nonconstant coefficients that describes the price of an American option. Finally we conduct some numerical simulations to verify the analysis of the method. The proposed method leads to a tridiagonal linear system at each time step and thus the option prices can be computed in a few seconds on a computer.
Binding properties of a nitrogen atom onto an anionic golden fullerene Au<sub>16</sub><sup>-</sup>
Kim, G.,Kang, S.H.,Lim, C.y.,Kwon, Y.K. North Holland ; Elsevier Science Ltd 2012 Chemical physics letters Vol.545 No.-
Using density functional theory, we examine the effects of a nitrogen atom adsorbed onto an anionic golden cage (Au<SUB>16</SUB><SUP>-</SUP>) on the properties of the nanocage. For the exohedral adsorption that is more stable than the endohedral doping, the bridge and hollow sites have larger binding energies than the atop sites by ~1eV. When the N atom is adsorbed on the cage, electrons are transferred to nitrogen from Au<SUB>16</SUB><SUP>-</SUP>. The nitrogen atom may move thermally from the exterior to the interior through a bridge site. In infrared spectra, exohedral doping causes greater intensities at higher frequencies than endohedral doping.
Spectroscopic identification and conversion rate of gaseous guest-loaded hydroquinone clathrates
Lee, J.W.,Choi, K.J.,Lee, Y.,Yoon, J.H. North Holland ; Elsevier Science Ltd 2012 Chemical physics letters Vol.528 No.-
The formation of hydroquinone clathrates with CO<SUB>2</SUB>, CH<SUB>4</SUB>, N<SUB>2</SUB>, and H<SUB>2</SUB> was investigated using X-ray diffraction, Raman spectroscopy, and solid-state <SUP>13</SUP>C NMR spectroscopy. Of the hydroquinones prepared at 5.0MPa, the CH<SUB>4</SUB>- and CO<SUB>2</SUB>-loaded hydroquinones show complete conversion to β-form hydroquinone clathrates while the N<SUB>2</SUB>-loaded hydroquinone shows only partial conversion; there is no indication of the formation of hydroquinone clathrate with H<SUB>2</SUB>. The CO<SUB>2</SUB>-loaded hydroquinone is fully converted to the β-form hydroquinone clathrate even at 1.0MPa. Solid-state <SUP>13</SUP>C NMR measurements of the hydroquinone clathrate samples prepared at different pressures reveal that the conversion rate for the formation of clathrate compounds from CH<SUB>4</SUB> and N<SUB>2</SUB> decreases with decreasing pressure.
Maaz, K.,Karim, S.,Kim, G.H. North Holland ; Elsevier Science Ltd 2012 Chemical physics letters Vol.549 No.-
Ni<SUB>x</SUB>Co<SUB>1-x</SUB>Fe<SUB>2</SUB>O<SUB>4</SUB> (x~0.3) nanoparticles were synthesized via chemical co-precipitation method. The particle size (d) was found to increase linearly with increasing annealing temperature. Magnetic studies revealed that the coercivity (H<SUB>C</SUB>) attains a value of 965Oe at ~18nm and then decreases for larger particles. The behavior of H<SUB>C</SUB> with d was attributed to the superparamagnetic nature of smaller nanoparticles, whereas for larger particles it was attributed to domain transformation mechanism. Both saturation magnetization (M<SUB>S</SUB>) and superparamagnetic blocking temperature (T<SUB>b</SUB>) were found to increase linearly with increasing size of the nanoparticles.
Kwon, O.M.,Park, M.J.,Lee, S.M.,Park, J.H. North-Holland ; Elsevier Science Ltd 2012 FUZZY SETS AND SYSTEMS Vol.201 No.-
This paper considers the problem of robust stability analysis for uncertain Takagi-Sugeno (T-S) fuzzy systems with time-varying delays. By constructing an augmented Lyapunov-Krasovskii functional and utilizing Finsler's Lemma, a novel criterion for delay-dependent robust stability of T-S fuzzy model with time-varying delay is derived in terms of linear matrix inequalities (LMIs). Also, a further improved stability criterion is proposed by utilizing free weighting techniques. Finally, three numerical examples are included to show the superiority of the proposed criteria.
Yeom, K.,Park, J.H. North-Holland ; Elsevier Science Ltd 2012 Future generations computer systems Vol.28 No.3
This paper describes a novel approach for managing self-organizing, distributed modular components in dynamically changing environments. The main concept is to fabricate a system which is composed of dynamically associated modular agents, that can migrate and reorganize by itself while the system is being executed. Association between modular agents can be varied and transmuted according to components' own migration schemes including deployment based on biological processes. This paper presents a self-organizable architecture, which can reorganize and reconfigure a system based on modular agents. It is contrived through observation of biological phenomena, and implements a platform to host the architecture in dynamically changing environments. We draw several key features of the modular agents, describe the principles of the modular agent based self-organizable framework, and depict how the proposed framework satisfies the functional requirements of network applications, which are made of several agents. We also demonstrate the efficiency and scalability of the framework through examining some simulation results.
Ki, Y.J.,Choi, D.H.,Lee, Y.M.,Lim, L.,Song, H.,Koh, Y.Y. Elsevier/North-Holland Biomedical Press 2014 INTERNATIONAL JOURNAL OF CARDIOLOGY Vol.175 No.3
Objective: The aim of this study was to determine the associations of brachial-ankle pulse wave velocity (baPWV), high-sensitivity cardiac troponin T (hs-cTnT) and N-terminal pro-B type natriuretic peptide (NT-proBNP) with the development of adverse outcomes after percutaneous coronary intervention (PCI). Methods: The baPWV, hs-cTnT and NT-proBNP were analyzed in 372 patients who underwent PCI. The primary endpoint was cardiac death. Results: There were 21 events of cardiac death during a mean of 25.8months of follow-up. When the baPWV cut-off level was set to 1672cm/s using the receiver operating characteristic curve, the sensitivity was 85.7% and the specificity was 60.1% for differentiating between the group with cardiac death and the group without cardiac death. Kaplan-Meier analysis revealed that the higher baPWV group (≥1672cm/s) had a significantly higher cardiac death rate than the lower baPWV group (<1672cm/s) (11.4% vs. 1.4%, log-rank: P<0.0001). This value was more useful in patients with myocardial injury (hs-cTnT≥0.1ng/mL) or heart failure (NT-proBNP≥450pg/mL). Conclusions: The results of this study show that high baPWV is a predictive marker for cardiac death after PCI.