의학전문대학원의 교육과정 개발

문경래 朝鮮大學校 附設 醫學硏究所 2006 The Medical Journal of Chosun University Vol.31 No.3

한국인에서 발생한 만성 B형 간염 환자에서 테노포비어의 단기 치료 효과

주종석,강성훈,김석원,신해진,이엄석,김석현,이병석,이헌영 조선대학교 의학연구소 2014 The Medical Journal of Chosun University Vol.39 No.3

The aim of this study was to evaluate the efficacy of tenofovir in HBV patients at 12 months after treatment. A total of 122chronic hepatitis B patients who took tenofovir for at least 12 months were enrolled. We measured ALT levels, HBeAg, anti-HBe, HBV DNA, and serum creatinine at six and 12 months after treatment. The virological response rate at six and 12 months after treatment in naïve patients was 27.1% and 41.7%, respectively. High virological response rate at six and 12months after treatment showed an association with initial low HBV DNA titer and initial negative HBeAg status.

동결견 환자의 외적유발인자 및 치료효과

김권영 조선대학교 부설 의학연구소 1999 The Medical Journal of Chosun University Vol.24 No.1

The purpose of this study was to identify the external causative factors of frozen shoulder and the effectiveness of treatment on the neck and shoulder. Forty eight patients with frozen shoulder were assessed by the range of motion of the shoulder joint and simple radiologic findings and electrodiagnostic studies. Forty five patients were abnormal in plain cervical spine and shoulder x-rays with cervical disc space narrowing in 17 Patients and cervical spondylosis in 15 patients, straightening of cervical lordotic curve, osteoporosis etc. Cervical radiculopathies were diagnosed in thirty six patients and normal in twelve patients in electrodiagnostic studies. Statistically significant increments of range of motion in the shoulder and decrement of the visual analog scale scores were observed in all patients after comprehensive rehabilitation((P<.05). Therapeutic protocol for those frozen shoulder patients must be individualized after correct diagnosis is made, therefore patients should have their necks examined and needed treatment of the cervical abnormalities and the shoulder region.

방광에 발생한 부신경절종 : 1예 보고 A Case Report

이미숙,이학봉,기근홍 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

Paraganglioma of the urinary bladder is a rare tumor. The authors experienced a case of nonfunctioning paraganglioma of the urinary bladder in a 67-year-old woman, complaining of painless gross hematuria as an only symptom. Cystoscopy disclosed a papillary, broad based polypoid tumor in the dome of the bladder. Histologically, the tumor is composed of a well defined nest of cuboidal cells ("llballen"seperated by a prominent sinusoidal vascular netwok. The individual cells have moderately abundant acidophilic granular cytoplasm with ovoid nuclei. Immunohistochemically, tumor cells are reactive for neuron-specific enolase, chromogranin and synaptophysin. The sustentacular cells at the periphery of neoplastic cell clusters are reactive for S-100 protein. The DNA analysis of this case was diploidy.

일부 미용업 종사자들의 피로증후군과 관련요인에 관한 연구

봉재환,김양옥,박종 조선대학교 부설 의학연구소 1998 The Medical Journal of Chosun University Vol.23 No.2

To investigated the fatigue syndrome of beauticians, the questionnaire survey for subjective symptoms and its associated factors was carried out 224 beauticians who were selected by quota sampling among beauticians practicing at Kwangju city. The questionnaire was composed of three groups of 10 items each, representing dullness and sleeping(group Ⅰ), difficulty in concentration(group Ⅱ) and bodily projection of fatigue(group Ⅲ). The results are as follows ; 1. The complaint rate of fatigue was the highest in "e strain(72.3%)"nd followed by "el stiff in the shoulders(69.2%) and "ole body feels tired"n the descending order 2. The average weighted score of fatigue complaints was the highest in group Ⅱ and followed by group Ⅲ and group Ⅰ in the descending order, suggesting the general type among the fatigue type. 3. The complaint rate of fatigue by the role of the jobs was the highest in hair designer and followed by novice beauticians. beauticians assistants and head beauticians in the descending order. 4. Those who unmarried, high educational status, unhealthy, irregular diet habits and short sleeping time complained of higher rate of fatigue syndrome(P<05). 5. The group with the short duration in experience of beauticians, worked central area within the city, longer duration in average daily work hours and dissatisfaction of a wage level, of a working environment and of an occupation had significantly higher average weighted scores of fatigue complaints(P<05). 6. The result of the multiple regression analysis, an average daily work hours, the site of a beauty shop and the satisfaction of an occupation were selected as significant variables associated with the fatigue syndrome of the beauticians(P<05). In conclusion, because factors associated with the job of beauticians influenced the fatigue syndrome, so to solve the fatigue syndrome of beauticians needed approach the job related factors.

소아 농흉의 임상적 고찰

김강호,박영봉,나창수 朝鮮大學校 附設 醫學硏究所 1988 The Medical Journal of Chosun University Vol.13 No.1

We made a clinical observation of 51 cases of empyema at the peaiatric department of Chosun University Hospital during the period from Jan. 1980 to Dec. 1987. The results were as follows; 1) The ratio of male to female was 1.8 : 1. The most frequent age group was 1∼3years (35.3%). 2) The cardinal symptoms were fever (88.2%), coughing(70.6%), and dyspnea(41.1%) Vomiting, diarrhea and abdominal distension were prominent in infancy. 3) The most frequent lesion predisposing to empyema was pneumonia (72.5%), being remarkable in staphylococcal empyma. 4) Hematologic findings on admission revealed hemoglobin level below 12gm%, leukyocyts count above 10,000㎣, and elevatedE.S.R. in most cases. 5) 31.2% of total patients showed growth of organisms. The most common causative agent was staphylococcus aureus (23.5%), which was relatively sensitive to Amikacin, Lincocin, Gentamicin, and Cephalothin. 6) The majority of patients were treated with antibiotics and closed drainage. The duration and amount of closed drainage were 11day and 180㎖ in mean values. the durations of hospitalization was 25 days.

吸煙이 肺機能에 미치는 影響(Ⅱ)

廉哲鎬,尹坪晋 朝鮮大學校 附設 醫學硏究所 1988 The Medical Journal of Chosun University Vol.13 No.1

This study was performed to examine the effect of cigarette smoking on pulmonary function, we undertook an analysis of 36 smokers and 33 nonsmokers whose ages were from 35 to 54 years. FVC (forced vital capacity), FEV_(1) (forced expiratory volume for 1 second), FEF_(200∼1200)(forced expiratory flow, 200∼1200 milliliters), FEF_(25∼75)%, and FEV_(1)/FVC% were calculated by determining the distance from the point of maximum inspiration to the point of maximum, expiration with survey spirometer, and expressed in terms of BTPS. The followings were the rusults obtained from this study. 1. Generally, FVC showed no significant difference between smoking group and nonsmoking group, but in age group 50 to 54 years, smoking group was significantly diminishsd compared with nonsmoking group. 2. In aga group 35 to 39 yeard, 45 to 49 years and 53 to 51 years, FEV_(1) and FEV_(1)/FVC% in smoking group were significantly diminished compared with nonsmoking group. 3. FEF_(200∼1200) showed almost no difference between smoking group and nonsmoking group. 4. In age group 35 to 39 years and 50 to 54 years, FEF_(25-75)% in smoking group was significantly diminished compared with nonsmking group.

기질성 정신장애가 동반된 Sheehan씨 증후군 1례

이나영,박동건,이창인 朝鮮大學校 附設 醫學硏究所 1987 The Medical Journal of Chosun University Vol.12 No.1

The authors experienced a case of acute psychotic state with delusion, hallucination, and cognitive deficit accompanied by gonadal, thyroidal deficiency in a 36 year-old housewife who had suffered from massive bleeding after delivery 6 years ago. The clinical symptoms were improved within 2 weeks after hormonal replacement therapy, administration of antipsychotics and have not recurred after immediate discontinuation of antipsychotics till now. So, the authors reported this patient as a case of Sheehan's syndrome associated with organic mental disorder.

일부 여자 중학생의 초경에 대한 불안정도와 적응 및 태도에 관한 관계연구

박경신,정영 朝鮮大學校 附設 醫學硏究所 1987 The Medical Journal of Chosun University Vol.12 No.1

The purpose of this research is to analyze which variable influence on the level of anxiety at the time of menarche and the level of adaptation coping with the maturational crisis and the attitude toward menstruation for the middle school girls so as to provide some criteria from which some nursing oparational methods and nursing intervention methods could be drawn up. The subjects of this were 284 girls attending at the middle schools located in Chon-buk province and the data collection was done from 25th Aug. 1986 to lst Sep. the same year. The instruments used for this survey were Spielberger's State Trait Anxiety Inventory (S.T.A.I.) and the instruments the author has made of using relative references and which was tested by Cronbach's α reliability Lest. (α=0.66) The analysis of data was done using Percentage, ANOVA, Chi-square, Pearson's Correlation Coefficient and the result of the study were as follows; 1. the first hypothesis, "The higher tha level of knowledge of menarche, the level of anxiety would be lower," was supported. (r = -0.151, P < 0. 05) 2. The second hypothesis, "The lower the level of anxiety at the time of menarche, the level of adaptation of menstruation would be higher" was supported. (r = -0.307, P < 0.05) 3. The third hyothesis, "The lower the level of anxiety at the time of menarche, the attitude toward menstruation would be positive," was supported (r = -0.256, P < 0.05) 4. THe fourth hypothesis, "The client appropriatly educated about sex in advance, would have higher level of adaptation and positive attitude toward menarche," was supported. (Adaptation : r = 0.115, P <0.05 Attitude : r = 0.391, P < 0.05)

도시 근로자의 스트레스 생활사건과 건강상태와의 관계연구

김인숙,주경옥,나덕미 朝鮮大學校 附設 醫學硏究所 1989 The Medical Journal of Chosun University Vol.14 No.1

The purpose of this study was to find the relationship between stressful life events and health status. The samples used for this study were randomly sampled 136 questionnaires of workers who worked at eight banks located in Kwang-Ju from 28th July to 9th August. 1986. Two instruments used in this study were as follows; first, Holmes & Rahe(1967)'s S.R.R.S was translated and amended. Second, modification of Cornell Medical Index was used to measure health status. The results of this study were as follows; 1. The first hypothesis, stressful life events will depend on general characteristics(age sex, marital status, socio-economic status) showed the significance according to sex(t=.396, P<.05) and educational level(F=.639, p<.05), therefore it was partially accepted. 2. The second hypothesis, health status were changed in proportion to stressful life events, was not significant. 3. As the result of measuring the stressful life events the average value were ranged from 69.15 to 6.50.Personal & social problems (69.15), home & family problems(52.05) showed relatively high value and religious problems(6.50) showed relatively low value. 4. As the result of measuring the health status, average rate of appeal was 13.34. Measured the rate of physical and mental health problems of health status, the average of them were 8.32 and 5.02. 5. The relationship between socio-economic status and stressful life events was not significant.