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      • KCI등재

        Static aerodynamic force coefficients for an arch bridge girder with two cross section

        Jian Guo,Minjun Zhua 한국풍공학회 2020 Wind and Structures, An International Journal (WAS Vol.31 No.3

        Aiming at the wind-resistant design of a sea-crossing arch bridge, the static aerodynamic coefficients of its girder (composed of stretches of π-shaped cross-section and box cross-section) were studied by using computational fluid dynamics (CFD) numerical simulation and wind tunnel test. Based on the comparison between numerical simulation, wind tunnel test and specification recommendation, a combined calculation method for the horizontal force coefficient of intermediate and small span bridges is proposed. The results show that the two-dimensional CFD numerical simulations of the individual cross sections are sufficient to meet the accuracy requirements of engineering practice.

      • KCI등재

        Effect of sintering temperature and ccalcium oxide content on microstructure and properties of geopolymer porous ceramics

        Zhenfan Chen,Shaofeng Zhua,Qingqing Wang,Xianbiao Wang 한양대학교 청정에너지연구소 2024 Journal of Ceramic Processing Research Vol.25 No.1

        Geopolymer porous ceramics with high porosity were prepared using casting process with metakaolin as the main rawmaterial and coconut diethanolamide as the blowing agent. The effects of sintering temperature and calcium oxide contenton the phase composition, microstructure and physical properties of geopolymer porous ceramics were investigated throughX-ray diffraction, scanning electron microscopy, etc. The results show that for the samples without calcium oxide, thecompressive strength and volume shrinkage gradually increase, while the open porosity gradually decreases with the sinteringtemperature increases. After the green body was sintered at 1200 ℃ for 2 hours, porous ceramic product with compressivestrength of 22.9 MPa, open porosity of 41.8%, and leucite as the main phase was obtained. The addition of calcium oxide in thepreparation process not only accelerate the solidification of geopolymer gel slurries and make the pores distribute in the heightdirection more evenly, but also acts as a modifier to lower the crystallization temperature of leucite in the sintering process. When the relative mass of calcium oxide to metakaolin is 6%, after sintering at 1000 ℃ for 2 hours, porous ceramic productswith uniform pore size distribution containing leucite phase can be obtained. In addition, the potential of geopolymer porousceramics as adsorbing material was validated by adsorption experiment of Pb(Ⅱ) solution

      • KCI등재

        Growth of monolayer and bilayer MoS2 through the solution precursor for high-performance photodetectors

        Hailong Yan,Jinbing Cheng,Kejia Zhua,Ao Li,Tao Peng,Yongsong Luo 한국물리학회 2020 Current Applied Physics Vol.20 No.5

        Various studies suggest that the performances of TMDs are largely thickness dependent. In this paper, we develop a chemical vapor deposition method to synthesis monolayer and bilayer MoS2 flakes with a solution precursor. The MoS2 phototransistors were prepared to investigate their optoelectronic performance. The MoS2 photodetectors exhibit high detectivity of 2.44 × 1011 and a fast response/recovery time of 97 ms/291 ms. The photoresponsivity of bilayer MoS2 flakes was found up to 7160 A W−1. Our research will pave a pathway to control the layer numbers of other TMDs nanostructures, expand the application of high performance 2D materials.

      • Detection of Cancer Antigens (CA-125) using Gold Nano Particles on Interdigitated Electrode-based Microfluidic Biosensor

        Eon Soo Lee,Md Nasir Uddin Bhuyian,Durgamadhab Misra,Shiqiang Zhua,Harsimranjit Singh,Joo Un Lee,Debdyuti Mandal,Bharath Babu Nunna 나노기술연구협의회 2019 Nano Convergence Vol.6 No.3

        Integrating microfluidics with biosensors is of great research interest with the increasing trend of lab-on-the chip and point-of-care devices. Though there have been numerous studies performed relating microfluidics to the biosensing mechanisms, the study of the sensitivity variation due to microfluidic flow is very much limited. In this paper, the sensitivity of interdigitated electrodes was evaluated at the static drop condition and the microfluidic flow condition. In addition, this study demonstrates the use of gold nanoparticles to enhance the sensor signal response and provides experimental results of the capacitance difference during cancer antigen-125 (CA-125) antigen–antibody conjugation at multiple concentrations of CA-125 antigens. The experimental results also provide evidence of disease-specific detection of CA-125 antigen at multiple concentrations with the increase in capacitive signal response proportional to the concentration of the CA-125 antigens. The capacitive signal response of antigen–antibody conjugation on interdigitate electrodes has been enhanced by approximately 2.8 times (from 260.80 to 736.33 pF at 20 kHz frequency) in static drop condition and approximately 2.5 times (from 205.85 to 518.48 pF at 20 kHz frequency) in microfluidic flow condition with gold nanoparticle-coating. The capacitive signal response is observed to decrease at microfluidic flow condition at both plain interdigitated electrodes (from 260.80 to 205.85 pF at 20 kHz frequency) and gold nano particle coated interdigitated electrodes (from 736.33 to 518.48 pF at 20 kHz frequency), due to the strong shear effect compared to static drop condition. However, the microfluidic channel in the biosensor has the potential to increase the signal to noise ratio due to plasma separation from the whole blood and lead to the increase concentration of the biomarkers in the blood volume for sensing.

      • SCOPUS

        Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to Photofrin photodynamic therapy

        Busch, Theresa M.,Xing, Xiaoman,Yu, Guoqiang,Yodh, Arjun,Wileyto, E.Paul,Wang, Hsing-Wen,Durduran, Turgut,Zhua, Timothy C.,Wang, Ken Kang-Hsin Korean Society of Photoscience 2009 Photochemical & photobiological sciences Vol.8 No.12

        Photodynamic therapy (PDT) can lead to the creation of heterogeneous, response-limiting hypoxia during illumination, which may be controlled in part through illumination fluence rate. In the present report we consider (1) regional differences in hypoxia, vascular response, and cell kill as a function of tumor depth and (2) the role of fluence rate as a mediator of depth-dependent regional intratumor heterogeneity. Intradermal RIF murine tumors were treated with Photofrin PDT using surface illumination at an irradiance of 75 or 38 mW $cm^{-2}$. Regional heterogeneity in tumor response was examined through comparison of effects in the surface vs. base of tumors, i.e. along a plane parallel to the skin surface and perpendicular to the incident illumination. 75 mW $cm^{-2}$ PDT created significantly greater hypoxia in tumor bases relative to their surfaces. Increased hypoxia in the tumor base could not be attributed to regional differences in Photofrin concentration nor effects of fluence rate distribution on photochemical oxygen consumption, but significant depth-dependent heterogeneity in vascular responses and cytotoxic response were detected. At a lower fluence rate of 38 mW $cm^{-2}$, no detectable regional differences in hypoxia or cytotoxic responses were apparent, and heterogeneity in vascular response was significantly less than that during 75 mW $cm^{-2}$ PDT. This research suggests that the benefits of low-fluence-rate PDT are mediated in part by a reduction in intratumor heterogeneity in hypoxic, vascular and cytotoxic responses.

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