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      • KCI등재

        Brain Imaging Study on the Pathogenesis of Depression & Therapeutic Effect of Selective Serotonin Reuptake Inhibitors

        Meng Qi,Zhang Aixia,Cao Xiaohua,Sun Ning,Li Xinrong,Zhang YunQiao,Wang Yanfang 대한신경정신의학회 2020 PSYCHIATRY INVESTIGATION Vol.17 No.7

        Objective Predefining the most effective treatment for patients with depressive disorders remains a problem. We will examine the differential brain regions of gray matter (GM) in major depressive disorder (MDD) patients and the relationship between changes in their volume and the efficacy of early antidepressant treatment using magnetic resonance imaging (MRI).Methods 159 never-medicated patients with first-episode MDD and 53 normal control subjects (NCs) were enrolled. The brains were scanned by MRI and measured with the 17-item Hamilton Depression Rating Scale (HAMD-17) at baseline and after 2 weeks of treatment with selective serotonin reuptake inhibitor (SSRI)s, and the non-responder group and responder group were obtained. The patients were analyzed by voxel-based morphological (VBM) and SPSS software. Receiver operator characteristics (ROC) analysis was performed for the difference between the responder group and the non-responder group in the differential brain regions, and Pearson correlations were computed between volume size and HAMD score reduction rate.Results Smaller GM volume of the right superior temporal gyrus (STG), and the orbital parts of the right medial frontal gyrus and right inferior frontal gyrus were observed in MDD versus the NCs. The non-responder group demonstrated a significant volume reduction at the right STG compared with the responders, but no corresponding change in orbital part of right medial frontal gyrus and right inferior frontal gyrus. ROC analysis showed that Accuracy=71.2%. There was a positive correlation between the STG gray matter volume and the HAMD-17 score reduction rate (r=0.347, p=0.002).Conclusion The study results confirmed the local changes in brain structure in MDD and may initially predict the early treatment response produced by SSRIs as antidepressants.

      • SCOPUS

        Research on Energy Flow Optimization of Compound Storage System in Pure Electric Vehicle with Longitudinal Dynamics

        Meng Dawei,Zhang Yu,Zhou Meilan,Tian Xiaochen 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.12

        Aiming at short endurance mileage for electric vehicle, effected vehicle life because of battery excessive charging and discharging, the control method is put forward making use of super-capacitor to recovery regenerative braking energy, Hafei-Saibao electric vehicle is as example,seven kinds of topology with composite energy-single load are researched on power consumption, and the force condition of front and rear wheels is analyzed for front driving vehicle,the required energy of front wheel is detected to develop control strategy. On the basis of experimental data, co-simulation is achieved in the vehicle special simulation software, the experimental results show endurance mileage of improved car has increased by 34%, endurance mileage after being charged is 243 kilometer, the per hundred kilometers consumption has been decreased to 7.5 kW.h from 12 kW.h, the electrical consumption has been decreased by 37.5%, and the full load characteristics is optimized.

      • KCI등재

        Selaginella austrotibetica (Selaginellaceae), a new spikemoss from Xizang, China

        Meng-Hua Zhang,Jie Yang,Aleksandr Petrovich Shalimov,강종수,Xian Chun Zhang 국립생물자원관 2024 Journal of species research Vol.13 No.1

        Selaginella austrotibetica, a new spikemoss species from China, is described. The species is epipetric and was found on a moss-covered rocky cliff by a riverbank. Morphologically, it is unlike any anisosporophyllous species in the genus Selaginella. However, it resembles species of the S. sanguinolenta group, especially similar to S. sajanensis in gross morphology, except for the characters of strobilus. The molecular phylogenetic analysis clearly showed that S. austrotibetica was nested within the anisosporophyllous species clade, forming a sister relationship with the clade of S. vaginata and S. xipholepis, and distinct from the S. sanguinolenta group, including S. sajanensis. Although S. austrotibetica is sister to the clade of S. vaginata and S. xipholepis, the species can be clearly distinguished by its sparse leaves on branches, dorsal leaves that are broad-ovate, base obtuse to rounded, margin denticulate or very shortly sparsely ciliolate, and leaves that are slightly thick and shiny. Therefore, we described Selaginella austrotibetica as a new species and discuss its phylogenetic relationships within the genus Selaginella.

      • Meta-Analysis of the Association between H63D and C282Y Polymorphisms in HFE and Cancer Risk

        Zhang, Meng,Xiong, Hu,Fang, Lu,Lu, Wei,Wu, Xun,Wang, Yong-Qiang,Cai, Zhi-Ming,Wu, Song Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.11

        Background: Previous studies suggested that the H63D and C282Y polymorphisms in the HFE genes were susceptible to many cancer types, nevertheless, the present results were inconclusive. Thus, the present study was aimed to evaluate the association between the HFE polymorphisms (H63D and C282Y) and cancer risk via meta-analysis. Materials and Methods: We retrieved PubMed, Google Scholar, Embase and Web of Science databases for all eligible studies up to April 1, 2015. All the statistical analysis was conducted by STATA 12.0. Results: Finally, a total of 20 publications including 24 case-control studies, comprising 6,524 cases and 31,080 controls for HFE-C282Y polymorphism and 19 publications including 21 case control studies, comprising 5,648 cases and 14,257 controls for HFE-H63D polymorphism were enrolled in our analysis. An increased risk for overall cancer risk was identified in HFE-H63D polymorphism under allele contrast (D vs H: OR=1.153; 95%CI=1.031-1.289, Pheterogeneity=0.002), homozygotes vs wide type (DD vs HH: OR=1.449; 95%CI=1.182-1.777, Pheterogeneity=0.391), dominant model (DD+HD vs HH: OR=1.145; 95%CI=1.007-1.301, Pheterogeneity=0.002) and recessive model (DD vs HD+HH: OR=1.416 ; 95%CI=1.156-1.735, Pheterogeneity=0.549), as well as HFE-C282Y under homozygotes vs wide type (YY vs CC: OR=1.428, 95%CI=1.017-2.006, Pheterogeneity=0.220). In addition, in the stratified analysis by cancer type, an increased risk was identified in hepatocellular carcinoma and breast cancer in C282Y polymorphism, as well as pancreatic cancer in H63D polymorphism, whereas a decreased risk of colorectal cancer was identified in C282Y polymorphism. Conclusions: Present study suggested that H63D and C282Y polymorphisms associated with an increased risk of overall cancer. Nevertheless, well-designed study with large sample size will be continued on this issue of interest.

      • KCI등재

        Identification and sex expression profiles of olfactory-related genes in Mythimna loreyi based on antennal transcriptome analysis

        Zhang Yun-Ying,Guo Jin-Meng,Wei Zhi-Qiang,Zhang Xiao-Tong,Liu Si-Ruo,Guo Hui-Fang,Dong Shuanglin 한국응용곤충학회 2022 Journal of Asia-Pacific Entomology Vol.25 No.2

        To better understand the olfactory mechanism of Mythimna loreyi, a worldwide migratory pest, we for the first time conducted a large scale identification of olfactory-related genes and investigation of their sex expression profiles by transcriptomic analysis. A total of 42,832 unigenes were obtained by transcriptome sequencing, as sembly and annotation, with an average length of 1,229 bp and N50 of 2,086 bp. In particular, 138 olfactoryrelated genes were identified by homologous blasting, including 33 odorant binding proteins (OBPs), 16 che mosensory proteins (CSPs), 63 odorant receptors (ORs), 24 ionotropic receptors (IRs) and two sensory neuron membrane proteins (SNMPs). Further, by using differential gene expression (DGE) and fragments per kilobase per million fragments (FPKM) values to compare the transcript levels between female and male antennae, we found that 22 olfactory-related genes (9 OBPs, one CSP and 12 ORs) were sex biased, with 10 genes being male biased and 12 genes female biased. In addition, sex and tissue expression profiles determined by qPCR of 15 selected genes confirmed the reliability of sex expression profiles obtained by the transcriptomic analysis, and demonstrated that most olfactory-related genes were specifically or primarily expressed in antennae, suggesting their roles in olfaction, while a few genes were highly expressed in other tissues, implying their non-olfaction functions. This study provides an important basis for further functional study of olfactory genes in M. loreyi.

      • Luminescence properties of Eu<sup>2+</sup> in T-phase Ba<sub>1.3</sub>Ca<sub>0.7</sub>SiO<sub>4</sub> lattice from multiple crystallographic sites at different temperatures

        Zhang, X.,Meng, F.,Zhang, J.,Cai, P.,Seo, H.J. Elsevier Science Publishers 2016 Materials chemistry and physics Vol.177 No.-

        Eu<SUP>2+</SUP>-activated Ba<SUB>1.3</SUB>Ca<SUB>0.7</SUB>SiO<SUB>4</SUB> phosphor has been synthesized by high temperature solid state reaction method. The optical properties of (Ba<SUB>1.29</SUB>Eu<SUB>0.01</SUB>)Ca<SUB>0.7</SUB>SiO<SUB>4</SUB> are investigated using photoluminescence (PL), photoluminescence excitation (PLE) spectra and luminescence decay time measurement between 10 and 523 K. The blue emission band peaking at ~448 nm is observed to be asymmetric. It can be divided into three Gaussian bands with maxima at ~440 (Eu I), ~464 (Eu II) and ~503 nm (Eu III), which is in good agreement with that measured from low temperature at 10 K. The temperature dependence of the PL intensity is also measured. The thermal quenching of Ba<SUB>1.3</SUB>Ca<SUB>0.7</SUB>SiO<SUB>4</SUB>:Eu<SUP>2+</SUP> is about 235 <SUP>o</SUP>C. The PL decay times of 425, 455 and 570 nm emission at 10 K are 0.23, 0.28 and 1.00 μs. They can be attributed to the lifetimes of Eu I, Eu II and Eu III site, respectively. The decay times of the 425 and 455 nm emission almost remain constant at 10 K and 523 K. The decay times of the emission at 570 nm do not change a lot with increasing temperature up to 300 K, then decrease to 0.2 μs at 523 K Ba<SUB>1.3</SUB>Ca<SUB>0.7</SUB>SiO<SUB>4</SUB>:Eu<SUP>2+</SUP> is a candidate blue-emitting phosphor for white LEDs.

      • A study of luminescence from Eu<sup>3+</sup>, Ce<sup>3+</sup>, Tb<sup>3+</sup> and Ce<sup>3+</sup>/Tb<sup>3+</sup> in new potassium gadolinium phosphate K<sub>3</sub>Gd<sub>5</sub>(PO<sub>4</sub>)<sub>6</sub>

        Meng, Fangui,Zhang, Hongzhi,Chen, Cuili,Kim, Sun Il,Seo, Hyo Jin,Zhang, Xinmin Elsevier 2016 Journal of alloys and compounds Vol.671 No.-

        <P><B>Abstract</B></P> <P>New potassium gadolinium phosphate [K<SUB>3</SUB>Gd<SUB>5</SUB>(PO<SUB>4</SUB>)<SUB>6</SUB>] doped with Eu<SUP>3+</SUP>, Ce<SUP>3+</SUP>, Tb<SUP>3+</SUP> and co-doped with Ce<SUP>3+</SUP> and Tb<SUP>3+</SUP> phosphors were prepared by high temperature solid state synthesis. Phase purity of the powders was checked by X-ray powder diffraction. Luminescence and excitation spectra of samples were reported. In particular, the interaction mechanism between Eu<SUP>3+</SUP> ions was investigated in terms of the Inokuti–Hirayama model; it was found that the interactions between Eu<SUP>3+</SUP> can be assigned to dipole–dipole interaction. K<SUB>3</SUB>Gd<SUB>5</SUB>(PO<SUB>4</SUB>)<SUB>6</SUB>:Eu<SUP>3+</SUP> could act as a candidate for solid state lighting due to its strong absorption band in the near-UV region (350–400 nm). The energy transfer from Ce<SUP>3+</SUP> to Tb<SUP>3+</SUP> was confirmed and the mechanism was studied using Dexter's theory; it is concluded that electric dipole–dipole interaction predominates in the energy transfer process from Ce<SUP>3+</SUP> to Tb<SUP>3+</SUP> in the K<SUB>3</SUB>Gd<SUB>5</SUB>(PO<SUB>4</SUB>)<SUB>6</SUB> host. The energy transfer efficiency and critical distance were also investigated.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Optical properties of K<SUB>3</SUB>Gd<SUB>5</SUB>(PO<SUB>4</SUB>)<SUB>6</SUB>:RE<SUP>3+</SUP> are investigated for the first time. </LI> <LI> The interaction mechanism between Eu<SUP>3+</SUP> ions is attributed to dipole–dipole type. </LI> <LI> K<SUB>3</SUB>Eu<SUB>5</SUB>(PO<SUB>4</SUB>)<SUB>6</SUB> is a candidate phosphor for application to solid state lighting. </LI> <LI> There exists an efficient energy transfer from Ce<SUP>3+</SUP> to Tb<SUP>3+</SUP> (<I>η</I> is up to 95%). </LI> <LI> The mechanism of energy transfer process is electric dipole–dipole interaction. </LI> </UL> </P>

      • SCISCIESCOPUS

        Controlled synthesis of Co<sub>2</sub>C nanochains using cobalt laurate as precursor: Structure, growth mechanism and magnetic properties

        Zhang, Yajing,Zhu, Yuan,Wang, Kangjun,Li, Da,Wang, Dongping,Ding, Fu,Meng, Dan,Wang, Xiaolei,Choi, Chuljin,Zhang, Zhidong Elsevier 2018 Journal of magnetism and magnetic materials Vol.456 No.-

        <P><B>Abstract</B></P> <P>Cobalt carbides (Co<SUB>2</SUB>C and Co<SUB>3</SUB>C) nanocomposites exhibit interesting hard magnetic property, controlled synthesis of individual phase facilitates to clarify the magnetism of each, but it is difficult to obtain the single phase. We present a new approach to address this issue via a polyol refluxing process, using cobalt laurate as the precursor. The single phase Co<SUB>2</SUB>C magnetic nanochains self-assembled by nanoparticles are synthesized. The precursor is the key factor for controlling the growth kinetics of the Co<SUB>2</SUB>C nanochains. Cobalt, instead of cobalt carbides, is produced if cobalt chloride, acetate and acetylacetonate replace cobalt laurate as the precursor, respectively. The evolution of the growth process has been studied. In the formation of Co<SUB>2</SUB>C, first fcc-Co produces, then it transforms into Co<SUB>2</SUB>C by carbon diffusion process, and the produced carbon first exists in disordered state and then a small amount of them transforms into graphite. Saturation magnetization (<I>Ms</I>) of Co<SUB>2</SUB>C nanochains obtained at 300 °C for 20, 60, and 180 min are 27.1, 18.9, and 10.9 emu g<SUP>−1</SUP>, respectively. The decrease of <I>Ms</I> caused by increasing carbon content, and the carbon content are much larger than the stoichiometric ratio value of Co<SUB>2</SUB>C (9.2 wt%). The Co<SUB>2</SUB>C nanochains have mesoporous pore of 3.8 nm and the specific surface area of 48.6 m<SUP>2</SUP> g<SUP>−1</SUP>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The Co<SUB>2</SUB>C magnetic nanochains are synthesized using cobalt laurate as the precursor in TEG. </LI> <LI> The precursor of cobalt laurate is the key factor for controlling the growth kinetics of Co<SUB>2</SUB>C nanochains. </LI> <LI> Ms of Co<SUB>2</SUB>C nanochains obtained at 300 °C for 20, 60, and 180 min are 27.1, 18.9, and 10.9 emu g<SUP>−1</SUP>, respectively. </LI> <LI> The decrease of Ms is caused by increasing carbon content with increasing reaction time. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>We present a new approach to obtain single phase Co<SUB>2</SUB>C nanochains by using cobalt laurate as the precursor.</P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        The Damage Criterion Affecting Life Prediction of Fiber-Reinforced Al–Li Alloy Laminates Under Spectrum Loading

        Meng Weiying,Li Yupeng,Zhang Xiaochen,Shi Huaitao,Zhang Yu,Lv Xiao 한국항공우주학회 2020 International Journal of Aeronautical and Space Sc Vol.21 No.4

        Fiber metal laminates, as the new generation of aircraft structural materials, are widely concerned by material researcher. This paper presents a study on the life prediction problems of fiber-reinforced Al–Li alloy laminates under spectrum loading by applying the cumulative damage and residual strength models. Firstly, fatigue life performance of the laminate materials is tested under different loading cases. Then, the most advanced damage accumulation and residual strength models are summarized, which is applied to composite laminates. Some models are directly abandoned because the data needed for fitting model cannot be obtained by this experiment or the model formulation is prevented directly to the application for the spectrum blocks with free loading. Meanwhile, a cumulative damage model considering residual strength is modified accordingly based on the characteristics of life prediction under spectrum loading. To study the impacts of these models on the fatigue life prediction for fiber reinforced Al–Li alloy laminate under spectrum loading, the predicted accuracy of these models will be compared by applying them to life prediction problems of 2/1 laminate and 3/2 laminate. Results show that compared with other models, modified model improves the prediction accuracy especially for 3/2 laminate.

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