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Zachary Zeigler(Zachary Zeigler ),Malachi Votaw(Malachi Votaw ),Connor Dreos(Connor Dreos ),Lydia Durnil(Lydia Durnil ),Jamie Terran(Jamie Terran ),Danielle Akin(Danielle Akin ),Trevor Nordin(Trevor N 사피엔시아 2018 Exercise Medicine Vol.2 No.-
Objectives: Acute exercise can result in post-exercise hypotension (PEH) lasting up to 24-h. Whether exercise performed on consecutive days would lead to an accumulating PEH effect has yet to be determined. The purpose of this study was to compare daily exercise (DE) to exercise performed on alternating days (AE) and control (CON) on PEH. Methods: Sedentary men 18-30 yr with elevated blood pressure (BP) participated in this three-arm randomized cross-over trial. The primary comparison was PEH between three groups (CON, AE, DE) over time (day 1,2,3). Both exercise groups were prescribed the same exercise intensity (70-75%HRmax), and total duration of exercise (90min) on a cycle ergometer. DE performed exercise on three consecutive days (three bouts 30min). AE performed exercise on two alternating days (2 bouts 45min). Following exercise subjects remained in the laboratory for 1-h while BP was taken every 5-min. Results: Nine overweight (BMI=29.2±4.5kg/m2), young (22.7±2.4years), moderately fit (VO2peak=35.6±7.3 ml.kg.min), male subjects with elevated BP (126.2±10.4 and 73.3±6.4 mmHg) completed the study. There was a significant systolic BP condition by day effect such that on day three systolic BP (CON 119.0±9.3, AE 118.9±15.0, DE 115.0±11.9 mmHg), and diastolic BP (CON 71.9±6.6, AE 68.4±10.3, DE 67.6±6.2 mmHg) were lowest during the post-exercise DE condition (P<0.001). Additionally, DE saw a significant reduction of resting systolic BP between day 1 and day 4 (122.8±10.2 mmHg vs 113.1±12.0 mmHg; P=0.022, respectively) and a borderline significant reduction between day 1 and day 3 (122.8±10.2 mmHg vs 114.8±10.0 mmHg; P=0.051, respectively). DE saw a borderline significant resting diastolic BP reduction between day 1 and day 3 (73.2±7.2 mmHg vs 68.6±6.5 mmHg; P=0.058, respectively) and a significant reduction between day 1 and day 4 (73.2±7.2 mmHg vs 66.4±4.3 mmHg; P=0.022, respectively). Conclusions: In conclusion, the post-exercise BP lowering effect of the prior exercise session appeared to accumulate during DE such that day 3 was the lowest of all conditions and days.
Zachary Spiritos,Parit Mekaroonkamol,Bassel F. El-Rayes,Seth D. Force,Steven A. Keilin,Qiang Cai,Field F. Willingham 대한소화기내시경학회 2017 Clinical Endoscopy Vol.50 No.5
Esophageal cancer has a poor overall prognosis and is frequently diagnosed at a late stage. Conventional treatment for metastatic esophageal cancer involves chemotherapy and radiation. Local disease control plays a significant role in improving survival. Endoscopic spray cryotherapy is a novel modality that involves freezing and thawing to produce local ablation of malignant tissue via ischemic mechanisms. Spray cryotherapy has been shown to be effective, particularly for early T-stage, superficial esophageal adenocarcinomas. We present the case of a 72-year-old-male with locally recurrent stage IV esophageal adenocarcinoma and long-term survival of 7 years to date, with concurrent chemoradiation and serial cryoablation. He remains asymptomatic and continues to undergo chemotherapy and sequential cryoablation. The findings highlight the long-term safety and efficacy of cryotherapy in combination with chemoradiation, and suggest that cryoablation may have an additive role in the treatment of advanced stage esophageal adenocarcinoma.
Heavy Fermion Superconductivity: 5f vs 4f
Zachary Fisk,Yoshinori Haga 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.63 No.3
Heavy electron materials are the only class of materials in which we know where to look forsuperconductivity. We discuss the relation between single ion and dense Kondo heavy electronphysics, what sets the energy scale in these materials, the ways in which their low temperatureexotic superconductivity is a prototype for all highly correlated electron superconductivity and thesimilarities between the 4f and 5f heavy Fermion materials.
Maintenance-based prognostics of nuclear plant equipment for long-term operation
Zachary Welz,Jamie Coble,Belle Upadhyaya,Wes Hines 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.5
While industry understands the importance of keeping equipment operational and well maintained, theimportance of tracking maintenance information in reliability models is often overlooked. Prognosticmodels can be used to predict the failure times of critical equipment, but more often than not, thesemodels assume that all maintenance actions are the same or do not consider maintenance at all. Thisstudy investigates the influence of integrating maintenance information on prognostic model predictionaccuracy. By incorporating maintenance information to develop maintenance-dependent prognosticmodels, prediction accuracy was improved by more than 40% compared with traditional maintenanceindependent models. This study acts as a proof of concept, showing the importance of utilizing maintenance information in modern prognostics for industrial equipment.
Zachary Stephen Zeigler,Trevor Carroll Nordin 대한비만학회 2019 The Korean journal of obesity Vol.28 No.3
Background: Weight cycling (WC) is a widespread behavior associated with elevated laboratory blood pressure (BP). The impact WC may have on ambulatory BP (ABP) is unknown. Methods: Impact of self-reported WC history on ABP was assessed via cross-sectional nonexperimental design. Sixty-five women completed the Weight and Lifestyle Inventory (WALI) questionnaire. The WALI has been shown to be a reliable index of WC (r=0.87, P<0.001). Data were analyzed looking at WC both as a continuous and criterion variable, and subjects were dichotomized as either WC or non-WC (NWC). Results: WC (n=31) were older (39.7±8.9 vs. 33.1±11.3 years), had a higher percent body fat (47.1%±6.2% vs. 41.4%±7.8%), and were less fit (21.2±5.4 vs. 26.7±7.6 mL/kg/min) than NWC (n=34). No significant correlation between laboratory systolic BP (SBP, P=0.830) or diastolic BP (DBP, P=0.997) and WC was observed. A significant correlation between the number of WC and systolic ABP (r=0.326, P=0.010) and trend for diastolic ABP (r=0.238, P=0.065) was found. SBP (23% vs. 17%, P<0.001) and DBP (13% vs. 9%, P<0.001) load was higher for WC compared to NWC women. Conclusion: WC may deleteriously affect BP outcomes that might only be observed when ABP monitoring is used.
Femoral Vein Reconstruction for Aortic Infections
Zachary S. Pallister,Jayer Chung 대한혈관외과학회 2021 Vascular Specialist International Vol.37 No.1
While rare, abdominal aortic infections remain one of the most technically and emotionally challenging cases that a vascular surgeon may face. Secondary infections of either endovascular, or open aortic reconstructions range from 0.2% to 8%. Primary aortic infections are much more rare. Diagnosis can be elusive, depending upon the virulence of the causative microbes, and extent of the infection. Patients are often brittle, with immunocompromise and malnutrition prevalent in this patient population. The gold standard diagnostic test remains a computed tomographic angiogram. The mainstay of management requires vascular control, and wide debridement of all infected materials and revascularization. Multiple methods exist to reconstruct the vascular supply. The neo-aortoiliac system (NAIS) is attractive as it utilizes the patient’s own femoral veins to reconstruct the vascular supply after the infection has been extirpated. The procedure is demanding upon the patient and surgeons alike. Also, the rarity of aortic infections limit experiences the literature to centers of excellence. However, the NAIS resists infection well, leaving the patient without any remaining foreign bodies. No further costs for conduit are incurred. Moreover, multiple experiences show excellent durability. While comparative effectiveness literature remains sparse, we believe the NAIS to be the optimal method of revascularization for select patients. In this article, we will review the use of NAIS for primary and secondary aortic infections. In particular, we will emphasize procedural details to help enable the reader to apply this procedure most effectively to their own patients.
Alter-globalization in Southern Europe: The Case of a Social Movement that Does Not Move
Eduardo Zachary Albrecht 부산외국어대학교 지중해지역원 2017 The Mediterranean Review Vol.10 No.2
This paper introduces the politics of the Alter-globalization movement in Greece, Spain, and Italy through a series of interviews and vignettes from the field, and locates the movement within the broader socio-political spectrum. The movement is found to have an uneasy relationship to power due to a paradox between its rhetoric and the actual material interests of its adherents. The paper also explores the relationship between activists and society and finds that the movement occupies a ritualistic and liminal space. It is concluded that this dynamic risks undermining civic participation in democratic processes.
Jonathan Zachary Felthun,Silas Taylor,Boaz Shulruf,Digby Wigram Allen 한국보건의료인국가시험원 2021 보건의료교육평가 Vol.18 No.-
The coronavirus disease 2019 (COVID-19) pandemic has required educators to adapt the in-person objective structured clinical examination (OSCE) to online settings in order for it to remain a critical component of the multifaceted assessment of a student’s competency. This systematic scoping review aimed to summarize the assessment methods and validity and reliability of the measurement tools used in current online OSCE (hereafter, referred to as teleOSCE) approaches. A comprehensive literature review was undertaken following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews guidelines. Articles were eligible if they reported any form of performance assessment, in any field of healthcare, delivered in an online format. Two reviewers independently screened the results and analyzed relevant studies. Eleven articles were included in the analysis. Pre-recorded videos were used in 3 studies, while observations by remote examiners through an online platform were used in 7 studies. Acceptability as perceived by students was reported in 2 studies. This systematic scoping review identified several insights garnered from implementing teleOSCEs, the components transferable from telemedicine, and the need for systemic research to establish the ideal teleOSCE framework. TeleOSCEs may be able to improve the accessibility and reproducibility of clinical assessments and equip students with the requisite skills to effectively practice telemedicine in the future.
Spinal Epidural Abscess: A Review of Presentation, Management, and Medicolegal Implications
Sharfman Zachary Tuvya,Gelfand Yaroslav,Shah Pryiam,Holtzman Ari Jacob,Mendelis Joseph Roy,Kinon Merritt Drew,Krystal Jonathan David,Brook Allan,Yassari Reza,Kramer David Claude 대한척추외과학회 2020 Asian Spine Journal Vol.14 No.5
Spinal epidural abscess (SEA) is a rare condition associated with significant morbidity and mortality. Despite advances in diagnostic medicine, early recognition of SEAs remains elusive. The vague presentation of the disease, coupled with its numerous risk factors, the diagnostic requirement for obtaining advanced imaging, and the necessity of specialized care constitute extraordinary challenges to both diagnosis and treatment of SEA. Once diagnosed, SEAs require urgent or emergent medical and/or surgical management. As SEAs are a relatively rare pathology, high-quality data are limited and there is no consensus on their optimal management. This paper focuses on presenting the treatment modalities that have been successful in the management of SEAs and providing a critical assessment of how specific SEA characteristics may render one infection more amenable to primary surgical or medical interventions. This paper reviews the relevant history, epidemiology, clinical presentation, radiology, microbiology, and treatment of SEAs and concludes by addressing the medicolegal implications of delayed treatment of the disease.
Eduardo Zachary Albrecht 부산외국어대학교 지중해연구소 2011 지중해지역연구 Vol.13 No.1
이 논문의 목적은 세계화에 반대하는 운동과 이태리 나폴리 지역에서의 사회적이고 정치적인 전후사정 간의 관계를 규명하는 데 있다. 이 연구에서는 크게 두 가지 질문에 대한 대답을 추구하고 있다. 첫째는 어떻게 나폴리 지역에서의 사회적인 상황들이 지역 내의 항의 운동에 영향을 줄 수 있는가에 대한 것이고, 둘째는 그러한 항의 운동들이 나폴리 도시의 정치적인 상황에 어떤 영향을 미치는가에 대한 것이라고 할 수 있다. 이 두 가지 질문에 대해서 본 논문에서는 세 가지 요인들을 이용해 평가하려고 한다. 첫 번째 요인은 가족, 범죄 그리고 교회의 역할에 대한 것이다. 두 번째 요인은 나폴리 도시에 대한 민족적인 서술과 이 도시의 사회적인 체계이다. 마지막 세 번째 요인은 나폴리 도시에서의 정치적 운동과 저항 운동간의 관계이다. 이러한 질문과 요인들에 대한 본 논문의 결론을 말하자면, 반 세계화운동과 나폴리 지역에서 일어나는 항의 운동 사이에서는 정치적인 결과물이나 연속성을 찾아볼 수 없다는 것이다. 하지만, 나폴리 지역의항의 운동은 젊은 계층들이 참여했다는 점에서 심리학적인 면에서 매우 중요한 역할을 했다고 볼 수 있다. 왜냐하면 그 운동은 나폴리 지역의 젊은 중산층들에게 높은 수준의 범죄율과 권위 있는 위치에 있는 사람들의 부패 그리고 도시 내에서 보편적으로 발생하는 폭력에 대한 그들의 불만과 좌절감을 표현하는 데 일조하고 있다고 할 수 있기 때문이다. 이 연구는 저자가 나폴리에서 2002년 9월부터 2003년 7월까지 약 1년을 보내면서 참여 관찰과 질적 연구 중 하나인 대상자들과의 인터뷰를 통해 이루어졌고, 또한 그 해에 나폴리 도시에서 반세계화 운동으로 조직된 다양한 정치적인 항의운동에 참여하는 것을 통해 이루어졌다. 저자는 항의자들과 매일의 보통 일상생활에서 관계를 맺으면서 조사하였고, 그 기간 동안 도시의 항의자들과 일반 시민들 간의 100개 이상의 인터뷰 자료들을 수집할 수 있었다. 참고문헌들은 인류학과 정치학 두 분야 모두에서 사용되는 것으로 인류학 분야에서는 Italo Pardo and Thomas Belmonte의 연구에서 많은 도움을 받았고, 정치학 분야에서는 Edward Banfield, Isaia Sales and Robert Putnam를 비롯한 많은 여러 학자들의 연구에서 도움을 얻었다.