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      • KCI등재

        The Role of 5G for Digital Healthcare against COVID-19 Pandemic: Opportunities and Challenges

        Yushan Siriwardhana,Gürkan Gür,Mika Ylianttila,Madhusanka Liyanage 한국통신학회 2021 ICT Express Vol.7 No.2

        COVID-19 pandemic caused a massive impact on healthcare, social life, and economies on a global scale. Apparently, technology has a vital role to enable ubiquitous and accessible digital health services in pandemic conditions as well as against “re-emergence” of COVID-19 disease in a post-pandemic era. Accordingly, 5G systems and 5G-enabled e-health solutions are paramount. This paper highlights methodologies to effectively utilize 5G for e-health use cases and its role to enable relevant digital services. It also provides a comprehensive discussion of the implementation issues, possible remedies and future research directions for 5G to alleviate the health challenges related to COVID-19.

      • The Mechanism of a New Fodder Additive-Allium Sativum to Beef Cattle

        Yushan Jia 한국초지조사료학회 2009 한국초지조사료학회 학술대회논문집 Vol.2009 No.08

        Through the analysis of several blood paramiters (indexes) that were closely related to feed (daily ration) conversion of beef cattle, the results showed that the content of INS(Insulin), TAA(Total amino acid), LAA(Limiting amino acid)and GH(Growth hormone) in the blood would reach the maximum when if the addition of Allium sativum ranged from 66g/headㆍday to 84g/headㆍday and Akkuyn sadtium ranged from 0.3g/headㆍday to 0.4g/headㆍday.

      • KCI등재

        Green and Facile Fabrication of Thermal Superamphiphobic Nanofibrillated-cellulose/Chitosan/OTS Composites Through Mechano-Chemical Method

        Yushan Yang,Liang Shan,Huajie Shen,Jian Qiu 한국섬유공학회 2021 Fibers and polymers Vol.22 No.5

        Superamphiphobic nanofibrillated-cellulose/chitosan/OTS composite was successfully prepared throughmechano-chemical method pretreatment, freeze-thaw treatment, regeneration and freeze drying. The morphology, structure,chemical components, element variation and thermally stable property of the prepared nanofibrillated-cellulose/chitosan/OTS composite was characterized by scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR)and X-ray photoelectron spectroscopy (XPS) thermogravimetric/differential thermogravimetric (TG-DTG). Results indicatethat micro/nano-biomimetic structures of the prepared nanofibrillated-cellulose/chitosan/OTS composite were alike to themicromorphology of a lotus leaf. As-prepared nanofibrillated-cellulose/chitosan/OTS composite not only exhibitedsuperhydrophobic performance with a water contact angle (WCA) of 154 o and the surface exhibits self-cleaning ability withsliding angle of 6 o, but also had excellent superoleophobic behavior. What’s more, the nanofibrillated-cellulose/chitosan/OTS composite is resistant to high-temperature-humidity-resistant, outperforming original wood fiber.

      • KCI등재

        Seismic Performance of Desert-sand Autoclaved Aerated Concrete Block Wall Constrained by Precast Integral Construction Column

        Yushan Wang,Wenxing Zhu,Jianjun Cheng 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.9

        Considering the structural types and construction techniques used in common residential buildings in Xinjiang, the paper proposes a novel masonry structure, i.e., desert-sand AAC blocks constrained by a precast integral construction column. In order to study the seismic performance of the structure, five wall specimens with different constraints are designed and fabricated and further compared and analyzed in terms of failure mode, hysteretic performance, energy dissipation capacity, ductility, stiffness degradation, and other performance indexes. It has been determined from the results that under horizontal low-cycle repeated loading, the main failure cracks of the desert-sand AAC block wall constrained by the precast integral construction column are intersecting oblique cracks, and the cracks in wall failure penetrate along concrete blocks. The stiffness degradation rate of the wall constrained by the water-resistant gypsum construction column gradually decreases with increasing vertical compressive stress. The wall constrained by the water-resistant gypsum construction column with arranged steel bars has a desirable ductility. Under the same vertical compressive stress, the wall constrained by the water-resistant gypsum precast construction column with arranged steel bars has a significant energy dissipation capacity from cracking to the ultimate state. (4) A restoring force model is built for desert-sand AAC block walls constrained by the precast integral construction column using a three-fold line model, offering technical support for the elastoplastic seismic analysis of structures.

      • KCI등재

        Evaluation of Curtain Grouting Efficiency by Cloud Model - based Fuzzy Comprehensive Evaluation Method

        Yushan Zhu,Xiaoling Wang,Shaohui Deng,Mengqi Zhao,Xuefei Ao 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.7

        Because of the concealment and uncertainty of dam foundation grouting, the accurate evaluation of the quality of grouting construction is a major concern. Most of the previous studies pertaining to the assessment of grouting efficiency only take a single factor into account, and only a few efforts have been devoted to the comprehensive evaluation of grouting efficiency, which fail to consider the fuzziness problems caused by the complex relationships among indicators as well as the randomness problems caused by subjective consciousness. Therefore, the curtain grouting efficiency evaluation method considering the uncertainty in evaluation process is proposed which includes three main parts: 1) Based on conventional evaluation indicators of grouting efficiency, where groutability is introduced as a new indicator; 2) a fuzzy comprehensive evaluation method based on cloud model is developed, by which the fuzziness and randomness in assessment are organically combined; and 3) the fuzzy entropy was calculated for indicating the complexity of grouting efficiency level. Then, the proposed method is used to assess efficiency of the curtain grouting for a hydropower station in China, and compared with three other methods. The outcomes display the consistency, representativeness, robustness and superiority of this evaluation method, which make the evaluation results more scientific and objective.

      • CpG coupled N-glycosylation mutant of HCV E1-E2 as a potential therapeutic DNA vaccine with enhanced cellular and neutralizing immune responses

        Yushan Ren,Miao Lin,Yuanqin Min,Xiao-Lian Zhang 한국당과학회 2012 한국당과학회 학술대회 Vol.2012 No.1

        N-linked glycosylation of viral proteins have been implicated in shielding antigen epitopes and blocking neutralizing antibodies production and contribute to the evasion of HCV from the host immune response. In this study, the effects of N-linked glycosylation of Hepatitis C virus (HCV) envelope E1 and E2 proteins, the naturally poor immunogens, on the induction of specific immune response were examined. We constructed plasmids containing the genes encoding both wild type E1E2 proteins and mutated E1E2 proteins in which N-linked glycosylation sites are mutated individually or in combination by site-directed mutagenesis or coupled with CpG, a TLR9 ligand. The immunoreactivity of wild type E1E2 and mutated E1E2 proteins or coupled with immune activator CpG was analyzed in BALB/C mice using a DNA-based vaccination approach. We found that E1E2 specific N-glycosylated mutant induced much higher IgG titer than wild type (WT) E1E2. E1E2 mutant vaccinated mice developed a mixture of IgG1 and IgG2a, but CpG-E1E2 mutant and E1-E2 wild type dominantly developed IgG2a isotype. And CpG-E1E2 mutant significantly stimulated Th1-type response and specific CD8+T cells cytotoxic T lymphocytes (CTL) activities. More important we found that CpG-E1E2 mutant significantly induced much higher neutalizing antibody than E1-E2-WT and had the highest level of neutralizing antibodies among all groups. The monoclonal clonal antibody (McAb) were prepared from CpG-E1E2 mutant immunized mice and the main neutralizing McAb 1C2 had significantly neutralizing Ab activity with blocking HCVcc infection in Huh7.5.1 cells in vitro. Epitope mapping of binding of a neutralizing McAb 1C2 was also analyzed. Our data indicate that the presence of glycans at the surface of HCV envelope proteins could help explain how HCV evades the humoral immune response and why most HCV infections lead to chronicity. CpG have the ability to augment both neutralizing antibody and cellular responses of E1E2 mutant. The CpG-E1E2 mutant holds potential applicant for the development of therapeutic vaccine with enhanced cellular and neutralizing immune responses.

      • KCI등재

        Distributed control system architecture for deep submergence rescue vehicles

        Yushan Sun,Xiangrui Ran,Guocheng Zhang,Fanyu Wu,Chengrong Du 대한조선학회 2019 International Journal of Naval Architecture and Oc Vol.11 No.1

        The control architectures of Chuan Suo (CS) deep submergence rescue vehicle are introduced. The hardware and software architectures are also discussed. The hardware part adopts a distributed control system composed of surface and underwater nodes. A computer is used as a surface control machine. Underwater equipment is based on a multi-board-embedded industrial computer with PC104 BUS, which contains IO, A/D, D/A, eight-channel serial, and power boards. The hardware and software parts complete data transmission through optical fibers. The software part involves an IPC of embedded Vxworks real-time operating system, upon which the operation of I/O, A/D, and D/A boards and serial ports is based on; this setup improves the real-time manipulation. The information flow is controlled by the software part, and the thrust distribution is introduced. A submergence vehicle heeling control method based on ballast water tank regulation is introduced to meet the special heeling requirements of the submergence rescue vehicle during docking. Finally, the feasibility and reliability of the entire system are verified by a pool test.

      • SCIESCOPUSKCI등재

        Distributed control system architecture for deep submergence rescue vehicles

        Sun, Yushan,Ran, Xiangrui,Zhang, Guocheng,Wu, Fanyu,Du, Chengrong The Society of Naval Architects of Korea 2019 International Journal of Naval Architecture and Oc Vol.11 No.1

        The control architectures of Chuan Suo (CS) deep submergence rescue vehicle are introduced. The hardware and software architectures are also discussed. The hardware part adopts a distributed control system composed of surface and underwater nodes. A computer is used as a surface control machine. Underwater equipment is based on a multi-board-embedded industrial computer with PC104 BUS, which contains IO, A/D, D/A, eight-channel serial, and power boards. The hardware and software parts complete data transmission through optical fibers. The software part involves an IPC of embedded Vxworks real-time operating system, upon which the operation of I/O, A/D, and D/A boards and serial ports is based on; this setup improves the real-time manipulation. The information flow is controlled by the software part, and the thrust distribution is introduced. A submergence vehicle heeling control method based on ballast water tank regulation is introduced to meet the special heeling requirements of the submergence rescue vehicle during docking. Finally, the feasibility and reliability of the entire system are verified by a pool test.

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