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- 저자 : Yumura, (검색결과 4 건)
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De novo formation of basal bodies in <i>Naegleria gruberi</i> : regulation by phosphorylation
Kim, Hong-Kyung,Kang, Jeong-Gu,Yumura, Shigehiko,Walsh, Charles J.,Cho, Jin Won,Lee, JooHun The Rockefeller University Press 2005 The Journal of cell biology Vol.169 No.5
<P>The de novo formation of basal bodies in <I>Naegleria gruberi</I> was preceded by the transient formation of a microtubule (MT)-nucleating complex containing γ-tubulin, pericentrin, and myosin II complex (GPM complex). The MT-nucleating activity of GPM complexes was maximal just before the formation of visible basal bodies and then rapidly decreased. The regulation of MT-nucleating activity of GPM complexes was accomplished by a transient phosphorylation of the complex. Inhibition of dephosphorylation after the formation of basal bodies resulted in the formation of multiple flagella. 2D-gel electrophoresis and Western blotting showed a parallel relationship between the MT-nucleating activity of GPM complexes and the presence of hyperphosphorylated γ-tubulin in the complexes. These data suggest that the nucleation of MTs by GPM complexes precedes the de novo formation of basal bodies and that the regulation of MT-nucleating activity of GPM complexes is essential to the regulation of basal body number.</P>
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In-grid Demonstration of High-temperature Superconducting Cable
Ohya, Masayoshi,Ashibe, Yuichi,Watanabe, Michihiko,Yumura, Hiroyasu,Nakanishi, Tatsuo,Hirota, Hirofumi,Masuda, Takato,Ichikawa, Hiroshi,Mimura, Tomoo,Honjo, Shoichi,Hara, Tsukushi The Korean Institute of Electrical Engineers 2013 The Journal of International Council on Electrical Vol.3 No.2
In a national project that began in 2007, Tokyo Electric Power Company (TEPCO), Sumitomo Electric Industries (SEI) and Mayekawa Mfg. Corporation (MYCOM) aim to operate a 66 kV, 200 MVA HTS cable system in a power grid to demonstrate its reliability and stable operation. In order to verify the validity of the cable design, a 30 m HTS cable system was constructed and subjected to various tests. After the confirmation of the nominal current and voltage performance, a long-term operation test was performed to verify whether the HTS cable system is capable of handling the rated current and voltage for thirty years. A 250 m cable was manufactured for the in-grid demonstration, and shipping tests were successful. The cable system construction was completed at the Asahi substation (Yokohama, Kanagawa), and the in-grid demonstration will start in 2012.
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Hiroki Ago,Satoshi Ohshima,Kazuhito Tsukuagoshi,Masaharu Tsuji,Motoo Yumura 한국물리학회 2005 Current Applied Physics Vol.5 No.2
Single- and multi-wall carbon nanotubes have been synthesized by the gas-phase catalytic reaction of colloidal solutions of metalnanoparticles using a vertical ow reactor. The reverse micelle solution of the CoMo nanoparticles with the mean diameter of 11nm dissolved in toluene was injected directly into the reactor maintained at 1200.C. The nanoparticles and the solvent act as thecatalyst and carbon source, respectively. When the concentration of the thiophene additive is low (1 wt.%), the formation of SWNTbundles preferentially occurred. The SWNT bundles were present together with the relatively small metal nanoparticles with thediameter of 0.55.5 nm. It is likely that the original nanoparticles with the diameter of 11 nm break into smaller ones, 12 nm dia-meters, which is suitable for the SWNT growth. The synactic eect of Co and Mo was also observed.. 2004 Elsevier B.V. All rights reserved.PACS:81.07.De
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Aging increases oxidative stress in semen
Mitsuru Nago,Akane Arichi,Naoki Omura,Yuka Iwashita,Toshihiro Kawamura,Yasushi Yumura 대한비뇨의학회 2021 Investigative and Clinical Urology Vol.62 No.2
Purpose: As age increases, oxidative stress increases, sperm motility decreases, and DNA fragmentation increases. To date, reports of age-related effects on semen have focused on reactive oxygen species (ROS) or total antioxidant capacity (TAC) as indicators of oxidative stress. However, assessments of ROS and TAC must be considered within a more comprehensive context in order to correctly evaluate oxidative stress and interpret findings. In this regard, the purpose of this study was to investigate the relationship between the static oxidation reduction potential (sORP) and paternal age with the goal of using the sORP as an indicator of semen oxidative stress. Materials and Methods: Semen samples from 173 men were analyzed for the following parameters: volume, motility, and beat cross frequency (BCF). The sORP was measured by using the MiOXSYS™ system. The correlation between semen parameters and the sORP level was analyzed as a function of age. The rate of sORP positivity was compared between men <34 and ≥34 years of age, with a positive sORP defined as a level ≥1.38. Results: Volume, motility, and BCF were negatively correlated with age (p<0.001). The semen sORP level was positively correlated with age (p<0.05). The rate of sORP positivity was significantly increased in men ≥34 years of age compared with that in men <34 years of age (33% compared with 12%, respectively; p<0.01). Conclusions: The sORP may play a role in age-related decreases in semen parameters (volume, motility, and BCF). The rate of sORP positivity increased significantly after 34 years of age.
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