클라우드 컴퓨팅 환경에서 웹 어플리케이션을 이용한 장면전환 검출

엄유미(Eom Yumie),유성근(Yoo Sunggeun),박상일(Park Sangil),박구만(Park Gooman) 한국통신학회 2013 한국통신학회 학술대회논문집 Vol.2013 No.11

HEVC 비트 스트림 상에서의 장면전환 검출 기법 연구

엄유미(Eom, Yumie),유성근(Yoo, Sung-Geun),윤소정(Yoon, So-Jeong) 한국방송·미디어공학회 2014 한국방송공학회 학술발표대회 논문집 Vol.2014 No.6

The era of realistic broadcast with high fidelity has come after the wide-spread distribution of UHD display and the transmission of UHD experimental broadcast in CATV. However, UHD broadcast now has constraint because it requires much amount of bandwidth and data in broadcasting transmission and production system. Not only HEVC(High Efficiency Video Codec) which has more than two times higher compression rate but also cloud-based editing system would be the key to solve the problems above. Also, fast scene change detection of videos is needed to index and search UHD videos smoothly. In this paper, therefore, a method is proposed to index and search the scene change information of large volume UHD videos compressed with high-efficiency codec. Application usages of fast detection of scene change information in various UHD video environments are considered by using this algorithm.

건강한 한국인 여성에서의 골밀도와 혈청 렙틴의 연관성

이유미,김대중,김세화,안철우,차봉수,김경래,이현철,임승길 대한내분비학회 2003 Endocrinology and metabolism Vol.18 No.2

연구배경: 혈청 렙틴은 식욕억제 효과와 여러 기관에서의 기능 외에도 골대사에 중요한 영향을 주는 인자로 알려져 있다. 그러나 렙틴의 골대사에 관여하는 각 세포와 실제 사람의 골밀도와의 관계에 대한 논란은 많다. 이에 건강한 한국인 여성에서의 골밀도와 혈청 렙틴과의 관계를 살펴보고자 하였다. 방법: 만성질환이 없는 67명의 폐경 전 여성과 73명의 폐경 후 여성을 대상으로 하여 요추부 및 대퇴경부의 골밀도를 DNA를 이용하여 촬영하고 혈청 렙틴을 측정하여 비고 분석하였다. 결과: 폐경 후 여성에서만 요추부 골밀도와 혈청렙틴이 양의 상관관계를 보였으며 이 관계는 연령과체지방지수 및 폐경기간을 보정한 후에도 양의 관계를보이는 경향이었다. 또한 가장 낮은 혈청 렙틴 농도를 보인 폐경 후 여성의 경우 높은 농도를 보인 여성들에 비해 의미 있게 낮은 요추부 및 대퇴경부 골밀도를 보였다. 결론: 건강한 한국인 여성에서의 혈청 렙틴은 골밀도와 약한 양의 상관관계를 보였으나, 폐경 상태에 따라 달라짐을 볼 수 있었다. Background: Leptin is known to affect bone metabolism both centrally and peripherally. This study was performed to investigate the relationship between leptin and bone mineral density (BMD) in healthy premenopausal and postmenopausal Korean women. Methods: 140 women were recruited for a routine health check-up. Anthro-pometric and biochemical data were checked as usual. BMDs were measured by dual x-ray absorptiometry of the spine and femur in 67 premenopausal women and 73 postmenopausal women, in addition to their serum leptin levels. Results: Serum leptin level showed no correlation with BMD in premenopausal women, but there was a positive correlation betwen serum leptin and spinal BMD in postmenopausal women (r=0.468, p<O.001). After the correcting for age, body mass index, and duration of menopause, the serum leptin level and BMD still showed a positive correlation(r=0.217, p=0.088) although weak The women in the lowest quartile of serum leptin level showed significantly lower lumbar and femoral neck BMD. Conclusion: Leptin level seems to have a weak relationship with BMD showing different features in premenopausal and postmenopausal women (J Kor SOC Endocrinol 18: 177-183, 2003).

Association between low bone mass and aortic valve sclerosis in Koreans

Choi, Han S.,Rhee, Yumie,Hur, Nam W.,Chung, Namsik,Lee, Eun J.,Lim, Sung-Kil Blackwell Publishing Ltd 2009 Clinical endocrinology Vol.71 No.6

<P>Summary</P><P>Background </P><P>Osteoporosis or low bone mass has been associated with cardiovascular disease and calcification in several clinical studies. However, few studies have assessed the relationship between bone mass and valvular calcification. The aim of this study was to evaluate the relationship between low bone mass and aortic valve sclerosis in Korean men and women.</P><P>Methods </P><P>A total of 211 men and 117 women were included in this study. Each subject’s bone mineral density (BMD) was measured with dual-energy X-ray absorptiometry, and aortic valve sclerosis was assessed using transthoracic echocardiography. Association between low bone mass and aortic valve sclerosis was assessed with multivariate logistic regression analysis in this cross-sectional study.</P><P>Results </P><P>Of 328 total subjects enrolled in this study, 50 men (23·7%) and 18 women (15·4%) were found to have aortic valve sclerosis. The mean (±SD) BMD <I>T</I>-scores were −0·5 (±0·8) in men and −0·9 (±1·0) in women. After adjusting for covariates, only women with aortic valve sclerosis had significantly lower BMD <I>T</I>-scores than those without it. Multivariate logistic regression analysis showed that age, smoking and hypertension were independently associated with increased risk of aortic valve sclerosis in men. In women, however, logistic regression analysis showed that BMD <I>T</I>-score, as well as age, was an independent variable for aortic valve sclerosis. We also found that a <I>T</I>-score of less than −1·5 was significantly associated with increased risk of aortic valve sclerosis in women compared to normal <I>T</I>-scores.</P><P>Conclusion </P><P>Low bone mass might be independently associated with increased risk of aortic valve sclerosis in women, but not in men. Women with low bone mass should be further evaluated for the presence of aortic valve sclerosis and related cardiovascular diseases.</P>

The effect of topiramate monotherapy on bone mineral density and markers of bone and mineral metabolism in premenopausal women with epilepsy

Heo, Kyoung,Rhee, Yumie,Lee, Hyang Woon,Lee, Sang Ahm,Shin, Dong Jin,Kim, Won‐,Joo,Song, Hong‐,Ki,Song, Kijun,Lee, Byung In Blackwell Publishing Ltd 2011 Epilepsia Vol.52 No.10

<P><B>Summary</B></P><P><B>Purpose: </B> To investigate the effect of topiramate on bone mass and metabolism in premenopausal women with epilepsy.</P><P><B>Methods: </B> Thirty‐six women on long‐term (at least 1 year) topiramate monotherapy were compared with 36 women taking carbamazepine, 32 women taking valproate, and 36 age‐ and sex‐matched controls. Subjects completed bone mineral density (BMD) studies. Serum was analyzed for indices of bone metabolism.</P><P><B>Key Findings: </B> BMD Z‐scores, and serum 25‐hydroxyvitamin D and 1alpha,25‐dihydroxyvitamin D<SUB>3</SUB> concentrations did not differ among the groups. Serum calcium concentrations were significantly lower in patients receiving topiramate than in those receiving valproate, and in patients receiving carbamazepine than in those receiving valproate and controls. Patients taking topiramate had lower levels of parathyroid hormone compared with controls and those taking carbamazepine or valproate. Patients receiving topiramate had higher levels of bone‐specific alkaline phosphatase and osteocalcin when compared with controls and higher levels of C‐terminal telopeptide of type 1 collagen when compared with those taking carbamazepine or valproate. Patients receiving carbamazepine had higher levels of bone‐specific alkaline phosphatase compared with controls and those receiving valproate. Serum bicarbonate concentrations were significantly lower in patients receiving topiramate than in the other groups.</P><P><B>Significance: </B> Our results demonstrate that use of topiramate is associated with lower parathyroid hormone and bicarbonate concentrations along with mild hypocalcemia and increased bone turnover, which suggests that topiramate may have long‐term effects on bone.</P>

Severe Hypothyroidism Induced by Thyroid Metastasis of Colon Adenocarcinoma: A Case Report and Review of the Literature

YOUN, Jong Chan,RHEE, Yumie,PARK, Soo Young,KIM, Won Ho,KIM, Soo Jung,CHUNG, Hyun Cheol,HONG, Soon Won,LIM, Sung-Kil The Japan Endocrine Society 2006 Endocrine journal Vol.53 No.3

<P>An 85-year-old man who had undergone a right hemicolectomy for colon cancer presented with severe hypothyroidism and hoarseness 21 months after the operation. The serum thyrotropin (TSH) was markedly elevated to 118.14 μIU/mL and serum free thyroxine (fT4) level was markedly suppressed to 0.34 ng/dL. Symptoms of hoarseness and neck swelling were already evident 4 months prior at which time tests for normal thyroid function were performed. The patient was referred due to aggravated pain on his diffusely enlarged hard goiter. An enlarged thyroid with some calcification was noticed in the neck ultrasonography with multiple cervical lymphadenopathies. Core biopsy of the thyroid gland showed invasion of poorly differentiated adenocarcinoma cells. Immunohistochemical studies showed positive staining only for carcinoembryonic antigen (CEA). There were multiple lung parenchymal nodules and adrenal masses at the time of evaluation. The patient was started on palliative chemotherapy with thyroid hormone replacement and gradually became euthyroid. From these findings and the clinical observations, thyroid metastasis with hypothyroidism developing acutely from metastatic colon adenocarcinoma was diagnosed.</P>

Algorithm detecting low arousal states of car drivers based on the driver’s eye blinking pattern

Keisuke Suzuki,Kiichi Yamada,Yumie Minakami,Hiroyuki Kawamura 대한인간공학회 2010 대한인간공학회 학술대회논문집 Vol.2010 No.5

In this study, five kinds of state variables characterizing the eye blinking behavior for detecting low arousal level of car drivers were investigated. This investigation was carried out in a driving simulator for clarifying what kind of state variables are useful for designing the algorithm of awaking alarm, in terms of minimizing the missing alarms in low arousal condition and the excess alarms in awaking condition simultaneously. In applying the ratio regarding closing/opening time of eyelid and the variation of this ratio for designing the algorithm, the time frequency of the missing alarms was approximately 1.5 % and extremely lower than the conditions when the algorithm was based on the other state variables like the total time for eye closing or the opening rate of eyelid. The excess alarms in applying this algorithm are also lower than the other algorithms. An effectiveness of awaking alarm based on this algorithm was also evaluated and clarified that the awaking effects by the acoustic alarm evaluated in terms of the fluctuation of RRI (ECG) was not sufficient, and the methodology for awaking the driver should be studied.

Peripheral Effect of α-Melanocyte-stimulating Hormone on Fatty Acid Oxidation in Skeletal Muscle

An, Juan Ji,Rhee, Yumie,Kim, Se Hwa,Kim, Dol Mi,Han, Dong-He,Hwang, Jung Hee,Jin, Young-Jun,Cha, Bong Soo,Baik, Ja-Hyun,Lee, Won Tae,Lim, Sung-Kil American Society for Biochemistry and Molecular Bi 2007 The Journal of biological chemistry Vol.282 No.5

Plasma periostin associates significantly with non-vertebral but not vertebral fractures in postmenopausal women: Clinical evidence for the different effects of periostin depending on the skeletal site

Kim, Beom-Jun,Rhee, Yumie,Kim, Chong Hwa,Baek, Ki Hyun,Min, Yong-Ki,Kim, Deog-Yoon,Ahn, Seong Hee,Kim, Hyeonmok,Lee, Seung Hun,Lee, Sun-Young,Kang, Moo-Il,Koh, Jung-Min Elsevier 2015 Bone Vol.81 No.-

<P><B>Abstract</B></P> <P><B>Background</B></P> <P>Periostin is preferentially expressed by the periosteum, which mainly covers the long bones. Therefore, the role of periostin in osteoporotic fracture (OF) may differ depending on bone type. We performed a case–control study to investigate whether periostin can serve as a predictor of OF risk, particularly after dividing OFs into non-vertebral and vertebral fractures.</P> <P><B>Methods</B></P> <P>Among 532 consecutive postmenopausal women not taking any drug or without any disease that could affect bone metabolism, 133 cases with OF (<I>i.e.</I>, non-vertebral and/or vertebral fractures) and 133 age- and body mass index-matched controls were enrolled. Non-vertebral (<I>i.e.</I>, forearm, humerus, hip, and pelvis; n=81) and morphological vertebral (n=62) fractures were identified by an interviewer-assisted questionnaire and lateral thoracolumbar radiographs, respectively. Bone mineral density (BMD) and plasma periostin levels were also measured.</P> <P><B>Results</B></P> <P>Plasma periostin was markedly higher in subjects with non-vertebral fracture than their controls even after adjustment for BMD and potential confounders (<I>P</I> =0.006). Each standard deviation increment of plasma periostin was associated with a multivariable-adjusted odds ratio of 1.59 for non-vertebral fracture. The odds for non-vertebral fracture were 2.48-fold higher in subjects in the highest periostin tertile compared with those in the lowest periostin tertile (95% confidence interval=1.10–5.61). However, associations between plasma periostin and vertebral fracture were not observed, regardless of the adjustment model used. Consistently, plasma periostin levels were inversely associated with proximal femur BMD (<I>P</I> =0.007 to 0.030) but not lumbar spine BMD. In subgroup analyses, plasma periostin had no correlation with the levels of classical bone turnover markers.</P> <P><B>Conclusions</B></P> <P>Plasma periostin may be a potential biomarker of the risk of OF, especially in non-spinal skeletal sites, such as the limbs, rather than spine.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Subjects with osteoporotic non-vertebral fracture showed markedly higher plasma periostin levels than their controls. </LI> <LI> Subjects in the highest periostin tertile had a 2.48-fold higher risk of non-vertebral fracture. </LI> <LI> Vertebral fracture did not associate with plasma periostin levels, regardless of the adjustment model used. </LI> <LI> Consistently, plasma periostin levels were inversely associated with proximal femur BMD but not lumbar spine BMD. </LI> </UL> </P>

Is focused parathyroidectomy appropriate for patients with primary hyperparathyroidism?

Won Woong Kim,Yumie Rhee,Eun Jeong Ban,Cho Rok Lee,Sang-Wook Kang,Jong Ju Jeong,Kee-Hyun Nam,Woong Youn Chung,Cheong Soo Park 대한외과학회 2016 Annals of Surgical Treatment and Research(ASRT) Vol.91 No.3

Purpose: The aim of this study was to determine whether focused or complete parathyroidectomy was more appropriate and to compare follow-up data in primary hyperparathyroidism (PHPT). Methods: We retrospectively analyzed 225 operations for PHPT at Yonsei University Health System between 2000 and 2012. After excluding 93 patients, the remaining 132 were divided into 2 groups: those who underwent focused parathyroidectomy (FP) and those who underwent conventional parathyroidectomy (CP). We compared clinicopathological features; preoperative calcium, parathyroid hormone (PTH), phosphorus, vitamin D, 24-hour urine calcium, and alkaline phosphatase levels; postoperative calcium and PTH levels; pathologic diagnosis; multiplicity; and results of a localization study between the 2 groups. Results: There was no significant difference in the rates of development of postoperative persistent hyperparathyroidism (1/122 FP patients and 1/10 CP patients) between the 2 groups due to a technical reason (FP 0.8% vs. CP 10.0%, P = 0.146). Multiglandular disease (MGD) was uncommon in all cases (6 of 132, 4.5%). All MGD cases were diagnosed using a preoperative localization study. Sestamibi scan and ultrasonography sensitivity were 94.2% and 90.2%, respectively. Conclusion: We suggest that FP is appropriate in PHPT, except in cases of MGD if detected before the operation using preoperative imaging. Knowledge of hereditary PHPT and improved preoperative localization studies, such as high-resolution ultrasonography, contributed to the decision to perform FP rather than CP in all cases of unilateral results of the localizing study.