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Yue Lin,Wang Jing,Pan Kang,Zhang Xiaoming,Wang Zhouping,Xia Wenshui 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.4
Making use of chitosan (CS) and ethylenediaminetetraacetic acid (EDTA) as a reaction system, CS-EDTA nanoparticles were synthesized through a facile counterion complex coacervation method. Ag^+ could enter porous CS nanoparticles synthesized with this method, allowing Ag nanoparticles within chitosan nanoparticles were synthesized by reducing silver nitrate with chitosan. Because of the noncovalent interaction between CS and EDTA, the EDTA could be easily removed via dialysis against water, and pure core/shell-type Ag/CS nanoparticles could be obtained. The nanoparticles showed higher antibacterial activity toward E. coli than the active precursor Ag nanoparticles and CS.
Yue Lin,Yuanyuan Zhang,Qiongtao Song,Tao Song,Xue Han,Ying Zhang,Xuan Zhang,Xi Chu,Fenghua Zhang,Li Chu,Jianping Zhang 대한약학회 2017 Archives of Pharmacal Research Vol.40 No.10
To explore the cardiovascular protective effectsof Magnesium isoglycyrrhizinate (MI), especially theunderlying cellular mechanisms related to L-type calciumchannels and myocardial contractility, and to examine theeffects of MI on hERG K? current expressed in HEK293cells. We used the whole-cell patch clamp technique,video-based edge detection and dual excitation fluorescencephotomultiplier systems to explore the effect of MIon L-type Ca2? currents (ICa-L) and cell contraction in ratcardiomyocytes. We also examined the rapidly activatingdelayed rectifier potassium current (IKr) expressed inHEK293 cells using a perforated patch clamp. MI inhibitedICa-L in a dose-dependent manner, with a half-maximalinhibitory concentration (IC50) of 0.22 mg/ml, and themaximal inhibitory effect was 61.10 ± 0.59%. MI at aconcentration of 0.3 mg/ml reduced cell shortening by24.12 ± 3.97% and the peak value of the Ca2? transient by36.54 ± 4.96%. MI had no significant influence on hERGK? channels expressed in HEK293 cells at all testpotentials. MI exerts protective effects on the heart via theinhibition of ICa-L and cell shortening in rat cardiomyocytes. However, MI had no significant influence on IKr;thus, MI may exert cardioprotective effects without causingdrug-induced long QT syndrome.
Synthesis of Ag/TiO_2 Core/Shell Nanoparticles with Antibacterial Properties
Yue Lin,Wang Qiqiang,Zhang Xiaoming,Wang Zhouping,Xia Wenshui,Dong Yuming 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.8
Monodispersed Ag/TiO_2 core/shell nanoparticles were synthesized in solution via colloid-seeded deposition process using Ag nanoparticles as colloid seeds and Ti(SO_4)_2 as Ti-source respectively. Silver nitrate was reduced to Ag nanoparticles with N_2H_4·H_2O in the presence of CTAB as stabilizing agent. The titania sols hydrolyzed by the Ti(SO_4)_2 solution deposited on the surface of Ag nanoparticles to form the Ag/TiO_2 core/shell nanoparticles. Inductively coupled plasma atomic emission spectrometry (ICP-AES) showed low amount of Ag ion leaching from the Ag/TiO_2 core/shell nanoparticles. The Ag/TiO_2 core/shell nanoparticles indicated excellent antibacterial effects against Escherichia coli and maintained long-term antibacterial property.
Active Vibration Control of a Membrane Structure Using PVDF Actuator
Yuelin Zhang,Toshiki Hiruta,Itsuro Kajiwara,Naoki Hosoya 대한기계학회 2015 대한기계학회 춘추학술대회 Vol.춘계 No.-
To realize a vibration suppression of flexible structures like a membrane, the smart structures technology that uses material such as piezoelectric element is focused. In this study, a vibration control system using a PVDF film as an actuator for the membrane structure is proposed. To confirm the effectiveness of the proposed method, the control properties with H<SUB>∞</SUB> control for reducing single mode, 1st or 2nd mode vibration, are evaluated by using the non-contact laser excitation vibration test system. In the system, a high power pulse laser is used for producing an ideal impulse excitation and a laser Doppler vibrometer is used for measuring the response on the membrane. The obtained results show that the vibration suppression is achieved at each mode in all experiments. Therefore, the present method using the flexible piezoelectric element is effective to suppress the vibration of flexible structures.
Yuelin Song,Ping Yang,Ziya Peng,Wei Jiang 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.2
AH-32 steel has been widely used in ship and marine structures but not been extensively studied for low-cycle fatigue (LCF) crack growth characteristics. The objective here is to explore the evolution mechanism behind LCF crack propagation behavior under different load conditions, for which the investigation of experimental and numerical simulation is considered in a detailed manner. An analytical model is presented to consider the effect accumulative plastic strain for ship cracked plate subjected to high stress cyclic loading. Different numerical parameters are proposed to quantify stress–strain field near crack-tip, and an integral model is developed to calculate the magnitude of the compressive stress. The effect of the maximum and minimum load on crack closure level is analyzed. The results show that there is an excellent correlation between LCF crack closure parameter and the magnitude of the compressive stress in the plastic wake, which indicates the presented integral model provides a new way for LCF crack propagation analysis.
( Capt Yuelin Zhao ) 고려대학교 법학연구원 2011 The Asian Business Lawyer Vol.8 No.-
First, this paper introduces the situation of the regulations for preventing collisions at sea in China, including the enactment of COLREGs in China, the principle special rules for collision avoidance in China, and the education and training of COLREGs in China. Secondly, this paper introduces general practice of liability apportionment of collision cases in China. Finally, this paper introduces the general practice regarding the relationship between marine casualty investigation and civil liability apportionment in China.
Xing Fan,Jisu Seo,YueLin Li,Ahyun Ryu,Kyoungok Joo,Moonkyoung Park,Rhayun Song 한국간호과학회 2021 한국간호과학회 학술대회 Vol.2021 No.10
Aim(s): Physical and cognitive functioning are both indicators of aging process. Older adults experience abnormal declines in physical and cognitive functioning that increase their risk of dependence, subsequently quality of life. This study aims to explore the relationship between physical and cognitive functioning, and mediation effect of cognitive functioning on the relationship of physical functioning and health-related quality of life among older adults with mild cognitive impairment. Method(s): Seventy-nine older adults living in community participated in the study. Measurements included the self-reported questionnaire for physical functioning consisted of grip strength, one leg standing with eyes open (balance), and Timed Up and Go (mobility). Cognitive functioning was measured by Korean version of MOCA. SF-12 was used to assess physical and psychological components of quality of life (QOL). Data were using multiple regression and a simple mediation model applying the PROCESS macro for mediation. Result(s): Physical functioning explained 14.5% of variance in cognitive functioning. Physical and cognitive functioning together explained 22.4% of variance in physical component of QOL, 18.7% of variance in mental component of QOL. Indicators of physical functioning significantly related with cognitive functioning with balance (B=0.41, p=.02). Cognitive functioning had significant indirect effects B= 0.19, 95%CI (.491~.008) between balance and physical component of QOL, while the indirect effects was not significant with mental component of QOL (B=0.06, 95%CI -.107~0.332). Conclusion(s): The findings showed cognitive functioning had a significant mediating effects between the physical functioning and physical components of QOL. These findings have suggested that nursing intervention to improve physical functioning such as balance, mobility and grip strength may also improve cognitive functioning, consequently improving physical component of QOL for older adults with mild cognitive impairment. Further studies are warranted to explore the effects of health promotion programs designed to enhance physical and cognitive functioning in this population.