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Yu-Xiang Yang,Zhen-Hua Xu,Yu-Qian Zhang,Jing Tian,Li-Xing Weng,Lian-Hui Wang 한국미생물학회 2012 The journal of microbiology Vol.50 No.6
Quorum sensing (QS) has been a novel target for the treatment of infectious diseases. Here structural analogs of Pseudomonas aeruginosa autoinducer N-acyl homoserine lactone (AHL) were investigated for QS inhibitor (QSI) activity and a novel QSI was discovered, N-decanoyl-L-homoserine benzyl ester (C2). Virulence assays showed that C2 downregulated total protease and elastase activities, as well as the production of rhamnolipid, that are controlled by QS in P.aeruginosa wild-type strain PAO1 without affecting growth. C2 was also shown to inhibit swarming motility of PAO1. Using a microdilution checkerboard method, we identified synergistic interactions between C2 and several antibiotics, tobramycin, gentamycin, cefepime, and meropenem. Data from real-time RT-PCR suggested that C2 inhibited the expression of lasR (29.67%), lasI (21.57%), rhlR (28.20%), and rhlI (29.03%).
XIANG-YU MENG,ZE-WEI BAO,FU-SHENG YANG,ZAO-XIAO ZHANG 대한설비공학회 2011 International Journal Of Air-Conditioning and Refr Vol.19 No.2
A solar energy storage system based on metal hydrides was proposed in this paper. The numerical simulation of processes of energy storage and thermal release were carried out. The dynamic behavior of heat and mass transfer in the metal hydride energy system were reported. Some factors which influence the whole system performance were discussed. The paper also made an economic analysis of the system, the results proved that the large amounts of metal hydride materials and the configurations of metal hydrides energy storage system involve a critical situation from an economical point of view. Then further analysis, particularly regarding the performance optimization and new plant arrangement of the metal hydrides energy storage system, has to be developed in order to attain the economical feasibility of the proposal.
Granular Effects on Depositional Processes of Debris Avalanches
Yu-xiang Hu,Hai-bo Li,Shun-chao Qi,Gang Fan,Jia-wen Zhou 대한토목학회 2020 KSCE JOURNAL OF CIVIL ENGINEERING Vol.24 No.4
Debris avalanches generally have massive mobility and extensive deposited area, which have strong relation to the granular effect. The granular effect is an outcome from the interaction (based on frictional mechanism) among particles. Discrepancy of grain composition, for instance the difference of particle size and their proportion of particles, is a key factor to influence granular effect. A series of laboratory tests have been conducted to research the granular effects on depositional processes of debris avalanches containing fine- and coarse-grained particles. The velocity of debris front, the morphology characteristics and runout distance of the debris avalanche are considered in detail, and the mass parameter and the size parameter are introduced in analysis for the research of granular effect. The experimental results indicate that the granular effects can decrease the dissipation of momentum and increase the accumulation region, leading to further runout distance and more extensive deposited areas. Further, the velocity, the range of depositions of debris avalanches are larger than that in other conditions when the proportion of fine-grained particles is 30%, especially the materials consist of heterogeneous granular. It means there have a critical mass parameter in experiments which lead to the high efficiency of granular effects, and the granular effect is weakening in homogeneous granular composition.
Mechanical behavior of stud shear connectors embedded in HFRC
Yu-Liang He,Xu-Dong Wu,Yiqiang Xiang,Yu-Hang Wang,Li-Si Liu,Zhi-Hai He 국제구조공학회 2017 Steel and Composite Structures, An International J Vol.24 No.2
Hybrid-fiber reinforced concrete (HFRC) may provide much higher tensile and flexural strengths, tensile ductility, and flexural toughness than normal concrete (NC). HFRC slab has outstanding advantages for use as a composite bridge potential deck slab owing to higher tensile strength, ductility and crack resistance. However, there is little information on shear connector associated with HFRC slabs. To investigate the mechanical behavior of the stud shear connectors embedded in HFRC slab, 14 push-out tests (five batches) in HFRC and NC were conducted. It was found that the stud shear connector embedded in HFRC had a better ductility, higher stiffness and a slightly larger shear bearing capacity than those in NC. The experimentally obtained ultimate resistances of the stud shear connectors were also compared against the equations provided by GB50017 2003, ACI 318-112011, AISC 2011, AASHTO LRFD 2010, PCI 2004, and EN 1994-1-1 (2004), and an empirical equation to predict the ultimate shear connector resistance considering the effect of the HFRC slabs was proposed and validated by the experimental data. Curve fitting was performed to find fitting parameters for all tested specimens and idealized load-slip models were obtained for the specimens with HFRC slabs.
A Stability Study of the Longest Steel Truss Deck Cable-stayed Bridge during Construction
Xiang-min Yu,De-wei Chen,Zhi-zhou Bai 대한토목학회 2019 KSCE Journal of Civil Engineering Vol.23 No.4
For long-span cable-stayed bridges, the stability performance during construction is vital from the point view of structural safety. This paper presents an extensive study of stability performance during construction for the world longest steel truss deck cable-stayed bridge-Yachihe Bridge. Based on the finite element analysis, the Linear Elastic Stability (LES), Nonlinear Elastic Stability (NLES) and Nonlinear Inelastic Stability (NLIES) of the bridge have been investigated to identify the effects of geometry nonlinearity and material nonlinearity on the structural stability performance. In addition, the influences of temperature variations and static lateral winds on stability performance are also focused. The results show that: 1) Under design ambient temperature, the corresponding design of steel truss deck yields the minimum stability coefficients of LES, NLES and NLIES by 5.72, 4.64 and 2.96, respectively, corresponding to the completion of superimposed dead loads; 2) both the geometry nonlinearity and material nonlinearity have been identified to make negative effects on the stability performance and the material nonlinearity will reduce the structural stabilitycoefficient largely; 3) during construction, the rise and drop in temperature will increase and decrease the stability coefficients, respectively. NLIES is the most sensitive one to variations of temperature; and 4) the lateral static winds slightly reduce the stability coefficients of LES, NLES and NLIES.
Xiang-Yu LI,J. Wu,W.Q. Chen,Hui-Ying Wang,Z.Q. Zhou 국제구조공학회 2012 Structural Engineering and Mechanics, An Int'l Jou Vol.42 No.3
This paper examines the problem of a penny-shaped crack in a thermoporoelastic body. On the basis of the recently developed general solutions for thermoporoelasticity, appropriate potentials are suggested and the governing equations are solved in view of the similarity to those for pure elasticity. Exact and closed form fundamental solutions are expressed in terms of elementary functions. The singularity behavior is then discussed. The present solutions are compared with those in literature and an excellent agreement is achieved. Numerical calculations are performed to show the influence of the material parameters upon the distribution of the thermoporoelastic field. Due to its ideal property, the present solution is a natural benchmark to various numerical codes and simplified analyses.
Xiang Yu,Haizhou Wu,Jianhao Zhang 한국식품과학회 2015 Food Science and Biotechnology Vol.24 No.2
Monascus spp. are fungi, traditionally eaten in Asian countries, that have the the potential to be used as a nitrite substitute in meat-product processing. Effects of using Monascus ruber MJ-1 as a nitrite substitute on color, lipid oxidation and proteolysis of fermented meat mince were investigated in this study. After 4 days of fermentation, a* and L* values for the samples were significantly higher and lower than the values for the control, respectively; however, b* values were significantly lower than that of the control throughout the fermentation process (p<0.05). Furthermore, Monascus ruber MJ-1 fermentation decreased the thiobarbituric acid reactive substances (TBARs) value and increased the myofibril fragmentation index (MFI) value of meat mince significantly (p<0.05). SDS-PAGE results further indicated that myofibrillar proteins were degraded during fermentation, while sarcoplasmic proteins were not. These results suggest prospects for the broad application of Monascus as a nitrite substitute in meat processing.