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Yu Quan,Wei-Jie Guo,Lin He,Zhe-Zhi Jin 영남수학회 2022 East Asian mathematical journal Vol.38 No.1
This paper is based on Yanbian University's physical test data, and uses statistical analysis methods to study the relationship between college students' physical test scores to promote college physical education. Firstly, using gender as categorical variables, we conduct a general analysis of students in different majors and different grades, and obtain the advantages and disadvantages of male and female college students; then we use Decision Trees and Random Forest algorithms to conduct modeling analysis to provide valuable suggestions for relevant departments of the university. the aiming of this research analyzing about the undergraduates physical test is that giving universities the targeted suggestions to improve the college graduate rate and promote the overall development of higher education, lay the foundation for achieving universal health.
Yu-Quan Yuan,Xiang-Guo Zeng,Hua-Yan Chen,An-Lin Yao,Yan-Fei Hu 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.11
The effect of cooling rate on the microstructure evolution of liquid Cu nanoparticles during their solidification process is investigated by using a molecular dynamics simulation based on the embedded atom method (EAM) potential developed by Foiles et al.. The potential energy analysis,the pair distribution function and the common neighbor analysis have been used. The results show that the solidification point increases with decreasing cooling rate and that the solidification of the microstructure of Cu nanoparticles varies with the cooling rate. The microstructure consists of fcc,hcp and bcc crystals or mixtures, though the fcc structure dominates, except in the amorphous state. An amorphous structure was obtained when the cooling rate reached 1.0 × 1013 K/s or higher while crystallization degree increased with decreasing cooling rate, and the total content of crystal structures reached to 95% when the cooling rate dropped to 4.0 × 1011 K/s, which was nearly a perfect crystal structure. The results also indicate that a single-crystal nanoparticle will not be obtained by quenching the liquid metal under various cooling rates.
Fluorescent image-based evaluation of gastric conduit perfusion in a preclinical ischemia model
Quan, Yu Hua,Kim, Minji,Kim, Hyun Koo,Kim, Beop-Min AME Publishing Company 2018 Journal of thoracic disease Vol.10 No.9
<P>Conclusions: We successfully created an ischemic animal model of the gastric conduit. Using this animal model, we evaluated the sensitivity and applicability of the fluorescent imaging system for observation and identification of ischemic areas during an esophagectomy.</P>
Yu, Min,Niu, Zhi-Min,Wei, Yu-Quan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12
We here document discovery of a new and simple model of tumor seeding involving the mouse peritoneum. Irradiated tumor cells administered by i.p. injection provided effective vaccination against peritoneal carcinomatosis and distal metastasis with colorectal carcinomas. In flow cytometric analysis, CD4+ and CD8+ T lymphocytes, macrophages and myeloid-derived suppressor cells (MDSCs), which are easy to obtain in the peritoneal cavity, were revealed to have significant differences between immunized and non-immunized mice and these contributed to antitumor responses. We also observed that both serum and peritoneal lavage fluid harvested from immunized mice showed the presence of CT26-specific autoantibodies. In addition, increase in level of TGF-${\beta}1$ and IL-10 in serum but a decrease of TGF-${\beta}1$ in peritoneum was found. Taken together, these findings may provide a new vaccine strategy for the prevention of peritoneal and even systemic metastasis of carcinomas through induction of an autoimmune response in the peritoneum.
Quan, Yu Hua,Kim, Byungji,Park, Ji-Ho,Choi, Yeonho,Choi, Young Ho,Kim, Hyun Koo Informa Healthcare 2014 Experimental lung research Vol.40 No.10
<P>In spite of severe side effects, chemotherapy is widely used as a major anticancer treatment in non-small cell lung cancer (NSCLC). In order to enhance the therapeutic properties and reduce side effects, enormous efforts have been devoted to direct anticancer agents specifically to tumor tissues by the use of nanoparticles, or cancer cell marker attached drugs. However, cell-specific chemotherapy is still in its infancy and is not applicable to all types of cancers due to the complexity of the cancer occurrence and progress. In this study, we demonstrate that hyaluronan (HA)-conjugated cisplatin has highly selective and sensitive anticancer effects in NSCLC cells that overexpress the trans-membrane receptor, CD44, as HA is a specific ligand for CD44. In proliferation experiments, HA-conjugated cisplatin showed dramatic cell viability decreases (from 100% to 42.31%) in H1299 cells, which overexpress CD44, whereas no such change was observed in A549 and HFL1, which have little to no expression of CD44. More importantly, conjugation with HA decreased the dosage concentration of cisplatin by 50-fold for both cytotoxic and anti-metastatic effects. In addition, HA-cisplatin conjugate treatment selectively decreased migration (from 100% to 7.8%) and invasiveness (from 100% to 21.4%, respectively) of H1299. Based on our experimental results, we strongly believe that HA-cisplatin conjugate is a potential anticancer chemo-agent, which target CD44 overexpression in NSCLC, with minimal side effects and high therapeutic properties.</P>
조선족 대학(원)생의 언어 사용 및 경험에 기반한 정체성 연구 -바흐친의 이데올로기적 되어가기를 중심으로-
전옥 ( Quan Yu ) 이중언어학회 2021 이중언어학 Vol.83 No.-
This study aims to show how to formate and negotiate their own identity based on the current state of language use and educational experience of the Korean-Chinese. For academic purposes, based on Bakhtin’s dialogism that devotes their Korean language learning and usage experience to Chinese Korean-Chinese college students who are studying and living in Korea for academic purposes, language learning is fundamentally social, starting from the point of view of the formation of identity and negotiation. Most of the participants in the study had a background of bilingualism, and in the process of completing their studies in Korea, they felt the difference between Korean and Chinese. It is a process that changes gradually. Therefore, in order to find out about the process, this study attempts to visualize the process of negotiation and formation by looking at the process of becoming ideological which constitutes participants ‘inner-persuasive discourse’ through the selective assimilation from their discourse. (Kyunghee University)