Expansin 유전자를 이용한 담배의 형질전환과 형질전환체 선발

백승준, 김보미, 장종오, 엄유리, 석영선, 이이 충북대학교 연초연구소 2008 煙草硏究 Vol.21 No.-

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영재반 중학생의 설계과정(Design Process) 기반 창의적 문제해결 질적 사례 연구

유재영,최준섭 부산대학교 과학교육연구소 2012 교사교육연구 Vol.51 No.3

The purpose of this study was to provide an empirical model of the design process that is used by gifted middle school students in problem solving. In order to achieve this purpose, research questions were in four areas: First, what is the design process that students use for problem solving? Second, is it possible for students to solve problems through ‘sketching’, ‘conceptual drawing’, and ‘part drawing’? Third, what are the difficulties faced by the students when at the construction stage of the design process? Fourth, what is the observed design process model used by the students during the problem solving? The following results were obtained from this study: First, it was possible for students to solve problems through the design process model and the process in each stage was iterative. The most difficult problem solving process observed in this research was during the brainstorming-sketching process. Conceptual drawing and sketching a process for solving the problem was performed repeatedly, requiring much time and effort from the students. Second, while students would engage in ‘sketching’, ‘conceptual drawing’, and ‘part and elements drawing’ in their problem solving, they perceived that ‘sketching’ was the most important process. Third, students had the most difficulty during the construction stage of the problem solving process as they were the lack of ability to use the tools necessary to build and construct their work. Fourth, the study concluded that the model identified in the students’ design process based problem solving was: 1)problem 2) brainstorming (idea creation) 3) sketching 4) conceptual drawing 5) part drawing 6) making 7) problem solving, feedback existed on some stage. 이 연구의 목적은 학생들이 어떤 설계과정을 통해 문제해결을 하는지에 관한 경험적 설계과정 모형을 제공하는 것이며, 이러한 연구의 목적을 달성하기 위해 첫째, 문제해결을 위해 학생들은 어떤 설계과정을 거쳐 왔고, 설계과정 이동경로의 특징은 무엇인가?, 둘째, 스케치, 구상도, 부품도를 통한 문제해결은 가능한가?, 셋째, 설계과정 중 제작을 통한 문제해결 사례에서 학생들이 어려워했던 점은 무엇인가?, 넷째, 설계과정 기반 문제해결을 통해 확인된 설계과정 모형은 무엇인가? 에 대한 연구 문제를 제시하여 다음과 같은 연구 결과를 얻을 수 있었다. 첫째, 설계과정을 통한 문제해결을 하는 동안 각 단계별로 반복적인 순환과정이 존재함을 확인할 수 있었고, 문제해결을 위해 JH팀과 SD팀 모두 문제해결을 위해 브레인스토밍-스케치 단계에서 가장 많은 그림을 그렸고, 또한 스케치-구상도, 제작-스케치 과정에서는 문제해결을 위한 반복 작업을 수행하여 가장 많은 시간과 노력을 투자하고 있음을 확인할 수 있었다. 둘째, 스케치, 구상도, 부품도를 통한 문제해결은 가능하며, JH, SD팀 모두 스케치를 설계과정에서 가장 중요한 단계로 인식하고 있었다. 셋째, 제작을 통한 문제해결 단계에서 학생들이 가장 어려워했던 것은 작품 제작 시에 사용되는 공구사용의 미숙으로 파악되었다. 넷째, 학생들의 설계과정 기반 문제해결을 통해 확인된 모형은 비선형(nonlinear) 모형으로 나타났으며, 모형에서 나타나는 단계는 문제-브레인스토밍(아이디어 생성)-스케치-구상도-부품도-제작-문제해결 과정을 거치는 것으로 파악되었다.

한우 myostatin 유전자의 SNP 및 발현분석

유성란,정기철,상병찬,이준헌 충남대학교 농업과학연구소 2004 농업과학연구 Vol.31 No.2

Myostatin is a transforming growth and differentiation factor-β family member that acts as a negative regulator of muscle growth. Previously, mutations in the myostatin gene were known to be related to double muscling phenotypes in cattle. Because myostatin gene is highly related to muscle mass, also meat quality, in cattle, we sequenced whole myostatin mRNA and investigated the SNPs (Single Nucleotide Polymorphisms) in Korean cattle (Hanwoo). The results indicated that Hanwoo had an SNP in nt2385 and this mutation can be a useful marker with further verifications. We also investigated expression patterns of the myostatin gene from various muscle tissues and organs. Northern blotting results indicated that myostatin expression was restricted in muscles with variable expression levels. The results presented here can be used as a valuable information for meat quality related traits and muscle mass in cattle.

한의약 컨텐츠를 가미한 강원도 리조트형 웰니스 프로그램 제안

유준상, 권보인, 이재형 상지대학교 한의학연구소 2023 尙志韓醫論文集 Vol.11 No.1

Objectives: As interest in wellness tourism is increasing in Korea, we sought to propose a program with Korean Medicine Contents for eight resorts in Gangwon-do, which has forests and marine resources. Methods: The authors visited eight designated resorts in Gangwon-do, observed the facilities, and interviewed the people in charge. Questions and answers were asked and answered in the form of a questionnaire regarding any deficiencies in the interviews. Afterwards, the contents were analyzed and a Korean Medicine program suitable for each resort was proposed. Results: A total of 17 Korean Medicine Programs were proposed, of which the meditation/yoga program and diet/drink program tailored to each constitution were proposed to be applicable to all 8 resorts. The rest were proposed considering each resort's facilities, environmental characteristics, and main product programs. Conclusions: It appears that the ‘meditation/yoga program’ and ‘constitutional diet and beverage development’ sectors are programs that can be commonly carried out by all facility companies, and for this purpose, the Sasang constitution test and Korean medicine measurement within the resort in Gangwon-do are used to create a program linked to this. In addition, we believe that efforts to improve the program through verification of efficacy will be necessary in the future

L-Moment 법을 이용한 지점가뭄빈도 해석

유재성,강인식,박준일,신형우 慶尙大學校生産技術硏究所 1999 生産技術硏究所論文集 Vol.15 No.-

In this research, the drought analysis was derived with monthly rainfall data from 59 stations from the Korea meteorological Administration. the point frequency analysis was derived with L-moment's method and indicated the fitted probability distribution for 59 points. also estimating the probability drought rainfall of the duration(4, 6, 8, 10, 12 months) and return period(2, 5, 10, 20, 50, 100 years). Thus, indicated probability drought rainfall frequency figure for whole area of country.

연강우량 자료를 이용한 수문시계열의 특성 분석

유재성,강인식,박준일,신형우 慶尙大學校生産技術硏究所 1999 生産技術硏究所論文集 Vol.15 No.-

As the water resources planning is work out, it should have stationarity and randomness to be used hydrological time series data for frequency analysis or modeling which are kinds of probability analysis. But, in the case of domestic, we assume that the hydrological time series data is stationarity but, is not randomness, so it is usual to work out the hydrological analysis. Therefore, as a result, we can not be eliminate the possibility that the hydrological analysis brings about distorted results. Accordingly, in this research, to analysis the properties of hydrological time series data, the trend test, stationary and randomness test were used. The summary of results is as below. Result of the properties of hydrological time series data, in most of the points, the tendency is not indicated, the time series was revealed as randomness which does not have hydrological persistence as definitely stationary. But, from data of yearly rainfall, points for Taegwallyong, Ullungdo, both nonstationarity and persistence were indicated.

남성유방에서 발생한 침윤성 선암종 1 예 : Report of a case

정유경,문현준,전호종 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Male breast cancer is rare compared to female breast cancer, about 1% or all breast cane or. The cause of male breast cancer is as poorly understood, but several etiologic factors have been suggested in the literature. Proposed risk factors include exogenous estrogen exposure, Klinefelter’s syndrome, gynecomastia and familial clustering. All of the microscopic types identified in the female breast have been encountered in males : the most common type is infiltrating duct carcinoma. Most often, it presents as a painless lump and subareolar in origin. Comparison with female breast cancer reveals no difference with regard to incidence of positive axillary lymph nodes. However there is a sightly lower survival rate for men. The stage of disease is the only parameter that significantly affects outcome. We report a case of breast cancer arising right subareolar area in a 57 year-old male. There were no familial history, Klinefelter's syndrome and microscopic evidence of gynecomastia. Histologically, this tumor was infiltrating duct carcinoma disposed in nests sometimes glands .

제 1형 신경섬유종증 환자에서 발생한 위장관 간질종양 1예

원경준,이준,변유미,조민근,한경택,김원,홍란,임성철,김경종,김영대,박찬국,김만우 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

Gastrointestinal stromal tumor (GIST) is the most common non-epithelial neoplasm arising in the gastrointestinal tract, but this tumor is rarely seen in association with type l neurofibromatosis (NFl) Generally, the majority of GISTs are isolated neoplasm and they are sporadically found in the stomach, but the GISTs in NFl patients are usually multiple and usually found in the small intestine. We report a case of multiple GISTs in the jejunum of a 63-year-old woman diagnosed as NFl accompanied by complication of gastrointestinal bleeding, In this case, Patient had multiple cafe-au lait spots and neurofibroma on skin and had freckling on axilla and groin, and then, we made a diagnosis of NFl. Gastrointestinal bleeding is controlled by resection of multiple GISTs. Generally, only 3-5% of all gastrointestinal bleeding comes from the small bowel. Causes of small intestinal bleeding are angiodysplasia, neoplasm, NSAIDs induced ulcer etc. but, If patients have NFl accompanied by complication of gastrointestinal bleeding, GISTs on small bowel must be considered.

X-선 회절법에 의한 소결광내의 칼슘페라이트 생성에 미치는 Al_2O_3, SiO_2 및 MgO의 영향

朴埈賢,趙兪貞,尹晟燮,許完旭,金亨順 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.7

In order to elucidate the fundamental aspects of the minerals formation processes during sintering, the Fe_2O_3-CaO-Al_2O_3-SiO_2 system and the effect of MgO on synthesized iron ore sinter were studied by image analysis and X-ray diffraction method. Most existed calcium ferrite was identified to be a solid solution of CaO·2Fe_2O_3 with a small amount of solubility of Al_2O_3 and SiO_2. With an increase of the content of Al_2O_3 in the system, the amount of calcium ferrite was increased. On the other hand, the amount of calcium ferrite was decreased, and the amount of hematite was increased with increasing the content of SiO_2. Crystal structure of calcium ferrite with Al_2O_3 and SiO_2 was changed from monoclinic to triclinic as well as the unit cell volume shrank with fixing Al_2O_3 and increasing SiO_2. With increasing the content of MgO(1∼3 wt%), the amount of magnetite was increased and hematite was decreased but calcium ferrite was not changed.

교정용 밴드 제거 후 미생물 분포 및 치주 조직의 임상적 변화

양유미,김성식,전은숙,박수병 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.4

본 연구는 밴드 제거 직후 및 4주 경과 후 치주조직의 임상적인 환경변화와 미생물 분포 변화를 알기 위해 시행하였다. 최후방 구치에 밴드를 포함하는 고정식 교정 장치를 장착하고 교정 치료를 1년 이상 시행한 17명의 환자를 대상으로 하였다 (평균 나이 22세, 남자 6명, 여자 11명). 최후방 구치의 밴드를 제거한 직후와 제거 후 4주가 경과한 다음에 치주조직의 탐침 깊이와 출혈 빈도를 측정하였으며, 치은 연하의 치태를 채취하여 미생물의 분포를 조사하였다. 치주질환에 관련성이 깊은 미생물 중 Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola를 직접 Polymerase Chain Reaction 방법으로 존재 여부를 확인하였다. 밴드 제거 직후와 제거 후 4주가 경과한 시점의 치주조직의 탐침 깊이와 출혈 빈도, 병원성 미생물의 존재 여부를 통계적으로 비교하였다. 탐침 깊이와 출혈 빈도는 모두 하악 좌측 구치 협면에서 감소율이 가장 크게 나타났고, 상악 우측 구치 설면에서 감소율이 가장 작게 나타났다. 병원성 미생물 중 T. denticola가 밴드 제거 4주 후에 가장 높은 감소율을 보였으며, 하악보다 상악에서 감소율이 더 크게 나타났다. 이는 비록 밴드를 장착하여 치주 환경이 불량해졌다 하더라도 올바른 구강 위생 관리가 시행된다면 밴드를 제거한 후 정상적인 치주 상태로 회복될 수 있음을 예시한 것으로 생각되었다. Objective: The purpose of this study was to evaluate clinical and microbiological changes in periodontal tissue around the banded molars after debanding. Methods: This study included 17 young adult patients treated with fixed orthodontic appliances including bands on the last molars more than 1 years. Probing depth and bleeding frequency were measured and plaque samples were collected from the last banded molars in all quadrants of each patient. All the data were collected immediately after debanding and 4 weeks after debanding. Results: Using polymerase chain reaction based on 16S rDNA, the presence of Porphyromonas gingivalis, Tannerella forsythia and Treponema denticola was detected. After debanding, probing depth, bleeding frequency, and prevalance of periodontopathogens were reduced. Probing depth and bleeding frequency were most decreased in the buccal site of the mandibular left molar and were least decreased in the lingual site of the maxillary right molar. Conclusion: The results of this study indicated that proper management of oral hygiene after debanding can recuperate unfavorable periodontal condition caused by orthodontic treatment.