面單位 農村地域의 類型化에 관한 硏究 : 西部慶南을 中心으로 Based on Sobu Kyongnam

愼英喆,李裕根,黃龍鎭 진주산업대학교 1992 論文集 Vol.31 No.-

本 硏究에서는 行政 및 文化生活의 基礎自 治單位인 西部慶南 9개 郡의 100개 面을 標本으로 삼아 因子分析方法등 여러 數理分析技法을 使用하여 村落의 形想를 3개 그룹으로 區分하며 農村地域의 特性을 나타내고 諸 指標를 利用하여 面單位의 農村地域의 土地利用特性과 類型化를 行하였다. 그 結果를 要約하면 다음과 같다. l) 判別된 平野村 25개, 準山村 49개, 山村 20개는 成功化率 94.0%로 3개 그룹으로 效率的인 村落區分이 이루어졌다. 2) 上位 5개 因子의 特性別 地域區分은 제1因子(人口가 많은 평야지대) 제2因子(畜産業이 盛한 地域), 제3因子(農家率이 높은 地域), 제4因子(果樹. 草地造成地域), 제5因子(沓作이 많은 地極)로 區分되었다. 3) 地域의 類型化는 Al類型(53개 面), A2類型(22개 面), B1類型(6개 面), B2類型(2개 面), C1類型(14개 面), C2類型(2개 面),D1類型(1개 面)의 7개 類型으로 區分되었다. 이러한 各 類型別 空間分布의 特性은 該當 農村地域의 地域開發과 關聯된 政策 이나 開發計劃樹立時 그 地域特性에 맞는 發展戰略과 手段이 될 것이다. This study is purposed to investigate the charactristics of using farm land and the classification of the area of rural community in Myo˘n Unit. With materials and methods to study in this paper, Cases and variables are given. The cases of rural settlement in So˘bu Kyo˘ngnam are one hundred. The variables of structure factor are twenty-three. The cases according to analysis are analysised by method of discriminant, factor and cluster analysis. From this study, The results obtained are as follows. 1) The cases of rural settlement are divided three groups by discriminant analysis. There are twenty-five plains, forty-nine Semi plains and twenty Mountain villages in So˘bu Kyo˘ngnam. 2) Five upper factors are analysised factor 1(populous plain), 2(high animal husbandry), 3(high farmhouse rate), 4(frute tree & pasture), 5(rice paddy field) on factor scores by factor analysis. 3) One hundred cases in So˘bu Kyo˘ngnam are classified according to rural settlement. Seven types of classification are the type of A1(53), A2(22), B1(6), B2(2), C1(14), C2(2), D(l).

충수돌기에 발생한 비호지킨 림프종 1예

정유경,이미숙,김윤식,이미자,전호종 조선의대 1995 The Medical Journal of Chosun University Vol.20 No.2

澱粉용액의 리오로지적 性質에 관한 硏究

卞裕亮,李神榮,曺亨勇 연세대학교 대학원 1981 延世論叢 Vol.18 No.1

The viscometric behavior of rice starch solution was studied with the capillary tube viscometer operated under various pleasures. Heated starch solution ranged from 3 to 9wt% were used as samples and flow constants in an equation r=(1/K)(gcτ- gcτy)n were determined by a non-linear least square method using the digital electronic computer. The value of flow behavior index n was found to be 1.2 in all samples. In the case of 3 and 5 wt% solutions, the values of yield stress could be overlooked, but the values of τy were relatively large and increased with the increase in concentration from 5 to 9 wt%. The temperatue dependence of flow consistency index K measured at 30~80℃ were expressed by Arrhenius equation. The values of activation energy were 3.5 to 10.2 kcal/mol.

유해화학물질의 계통분석

박성우,박유신,이진훈,유재훈,김유나,오세진,이진숙,김남이,박종신,남금문,노동석 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

유해화학물질의 계통분석

박성우,박유신,이진훈,김남이,김유나,임미애,이상기,유재훈,진광호,신호상,노동석 內務部 國立科學搜査硏究所 2001 國立 科學 搜査 硏究所 年報 Vol.33 No.-

인체 췌장암세포주(Capan-1)의 증식에 미치는 amiloride의 억제효과

임대관,김신,김유리,노지훈,이지현,김지연,박무인,정근옥,박건영,구자영 고신대학교 의학부 2004 高神大學校 醫學部 論文集 Vol.19 No.1

Background/Aims Cytoplasmic alkalinization induced by activation of the Na+/H+anti porter which is stimulated upon the addition of growth-promoting agents, such as insulin, epidermal growth factor, phorbol ester, plays an essential role in the initiation on cell proliferation. In the present study the effects of amiloride, a specific and reversible inhibitor of Na+/H+antiporter, on the growth of human pancreatic carcinoma cell line, Capan-1 cells was examined and the effects of 5-fluorouracil (5-FU) were also studied. Cell cycle analysis was done to examine the mechanisms for the inhibitory effects of amiloride. Materials/Methods The growth of Capan-1 cells were examined by counting cell number on two and four days treatment with 1 μM, 5 μM, 10 μM, 20 μM, 40 μM, 80 μM, 160 μM amiloride, and 0.1 ㎍/㎖, 0.3 ㎍/㎖ 5-FU, after plating Capan-1 cells into 35-mm2 plastic dishes at d density of 10x104 cells/dish. The reversibility of the effects of amiloride was examined on two day to eight days treatment with 20 μM amiloride after seeding 2×104 cells/dish. Cell cycle analysis was done on the sells after four days treatment with 20 μM amiloride. Results Amiloride significantly inhibited the growth of Capan-1 cells in a dose-dependent fashion (p<0.05). The inhibitary effect of amiloride on the growth of Capan -1 cells was firstly shown at the concentration of 5 μM, which is not so higher than the concentration of 0.1-0.2 μM attainable by administration of usual dose of amiloride (5-10㎎). Forty-eight percent inhibition of growth was found at an amiloride concentration of 20μM after 4 days treatment, and ninety-three percent inhibition of growth was found at an amiloride concentration of 160μM after 4 days treatment. The inhibitory effect of amiloride on growth of Capan-1 cells was reversible since removal of amiloride by a media change after 48 hours treatment lead to significantly more growth than amiloride treated group (p<0.05). The reversibility of growth inhibition suggests that amiloride in not a non-specific cytotoxin for Capan-1 cells. Amiloride combined with 5-FU significantly inhibited the growth of Capan-1 cells in a dose-dependent fashion compared to an amiloride or a 5-FU alone (p<0.05). After four days treatment with 20 μM amiloride, the faction of cells in G0-G1 phase, S phase and G2-M phase was 47.3%, 35.8%, 16.9% respectively in the amiloride group (20 μM), and 44.3%, 37.1%, 18.6% in the control group. showing no significant differences between the two groups. Conclusions Amiloride significantly inhibited the growth of Capan-1 cells in a dose-dependent fashion, which was reversible. The reversibility of growth inhibition suggests that amiloride is not a non-specific cytotoxin for Capan-1 cells. The concentration of 5 μM, which is not so higher than the concentration of 0.1-0.2 μM attainable by administration of usual dose of amiloride (5-10㎎), which suggests amiloride or its analogues may be used alone or in conjunction with 5-FU for the treatment of pancreatic carcinoma. Further study is needed to clarify the effects of more potent analogues of amiloride on the growth of human pancreatic carcinoma cells.

ILP 프로세서에서 성능향상을 위한 조건실행에 관한 연구

이상정,김유신 순천향대학교 부설 산업기술연구소 1998 순천향 산업기술연구소논문집 Vol.3 No.3

In this paper, predicated execution and its effect for improving performance in ILP processors are studied. Predicated execution, which represents through if-conversion that conditionally executes parts of control flow graphs, transforms control dependency into data dependency. The larger basic block after if-conversion generally contains more amounts of parallelism, permitting the compiler to schedule instructions that are more parallel and use the processor resources better. To evaluate this, it is developed the simulator which supports predicated execution. Using the simulator, the performance effects of predicated execution are analyzed. The results show that the scheme with predicated execution increases performance by 21% over the scheme without it.

이차원전기영동법을 이용한 길항세균 Bacillus licheniformis DM3와 이의 항진균 활성 결여 돌연변이균주간 단백질 비교 분석

이영근,김재성,정혜영,장유신,장병일 한국환경농학회 2003 한국환경농학회지 Vol.22 No.3

항진균 활성균주를 선발하는 과정에서 DM3 균주를 대천 바닷가에서 수집된 진흙 시료로부터 분리하였으며 API 50CHB kit를 이용하여 동정한 결과 Bacillus licheniformis로 동정되었다. 이 균주는 12종의 식물병원성 진균에 대해 항균활성을 나타내었다. 감마선(^(60)Co)을 조사하여 항진균 활성 결핍 돌연변이체(mDM3)를 유도한 후, 이차원전기영동으로 단백질을 분석한 결과 DM3와 mDM3에만 존재하는 각각 4종과 3종의 단백질을 확인할 수 있었다. 2-DE 결과 B. licheniformis DM3에서 spot 1은 serine hydroxymethyltransferase(45.0 kDa), spot 2는 hypothetical protein(40.7 kDa), spot 3는 NifU protein homolog(15.4 kDa), 그리고 spot 4는 resolvase(12.5 kDa)와 상동성을 지닌 단백질로 동정되었고 B. licheniformis mDM3에서만 발현된 spot 5는 lysozyme(18.1 kDa)과 spot 6, 7은 alkyl hydroperoxide reductase(15.6 kDa)으로 동정되었다. B. licheniformis DM3에서 이들 단백질들의 항진균 활성 관련 여부를 규명하기 위해서 더 연구가 진행되어야 할 것으로 사료된다. In the course of screening for antifungal agents, a bacterial strain, DM3 was isolated from a mud sample collected at Daechon in Chungnam province and identified as Bacillus lichenifomris based on API 50CHB test. It has antifurgal activity against 12 plant pathogenic fungi in paper disc assay. At the 95% lethal dose of gamma radiation (^(60)Co, 10 kGy, D_(10)=2.32 kGy), the antifungal activity deficient mutant (mDM3) against Colletotrichum gloeosporioides was induced. From 2-D electrophoresis analysis, serine hydroxymethyltransferase(45.0 kDa), hypothetical protein(40.7 kDa), NifU protein homolog(l5.4 kDa), and resolvase(l2.5 kDa) horn ologous proteins were detected only in B. lichnifomris DM3. Lysozyme(l8.1 kDa) and dkyl hydroperoxide reductase(l5.6 kDa) homologous proteins were expressed uniquely in B. licheniformis mDM3. Further studies are needed to reveal that these proteins from B. lichenifomis DM3 could be closely related to the antifungal activity against plant pathogenic fungi.

Bacillus sp. MS202에 의한 Dinitroaniline계 제초제인 Pendimethalin의 부분환원

이영근,장화형,장유신,형석원,정혜영 한국환경농학회 2004 한국환경농학회지 Vol.23 No.4

토양과 지하수에서 pendimethalin의 지속성은 환경에 해로운 영향을 미친다. 경남 마산에서 분리한 pendimethalin분해 균주는 API CHB50 kit 시험, FAME 분석, 그리고 165 rDNA 염기서열분석 결과로 Bacillus sp. MS202로 잠정적으로 동정하였다. TLC, GC, 그리고 GC-MS 분석에 의해 Bacillus sp. MS202가 pendimethalin의 -NO₂를 -NH₂로 환원시킨다는 것을 알 수 있었다. 이는 일반적으로 알려진 호기성 미생물에 의한 pendimethalin 분해가 탈알킬화가 우선한다는 보고와 상반되는 새로운 결과이다. The persistence of pendimethalin in soil and ground water has an injurious effect on ecosystem. Pendimethalin-degrading bacterium was isolated from Masan, Gyeongnam province and temporarily identified as Bacillus sp. MS202 by the analysis of API CHB50, kit, FAME, and 16S rDNA sequence. From the analysis of pendimethalin metabolite using TLC, GC, and GC-MS, we found that the degradation of pendimethalin by Bacillus sp. MS202 did not result in the dealkylated form, but the formation of the reduced compound, 6-amino-2-nitro-N(1-ethylpropyl)-3,4-xylidine or 2-amino-6-nitro-N(1-ethylpropyl)-3,4-xylidine.

Bacillus lentimorbus WJ5의 감마선유도 돌연변이체들에서 공통으로 발현되는 방사선 관련 유전자의 microarray 분석

이영근,장화형,장유신,허재호,형석원,정혜영 한국환경생물학회 2004 환경생물 : 환경생물학회지 Vol.22 No.3

본 연구에서는 감마선으로 유도된 돌연변이체들에서 공통으로 발현되는 방사선 관련 유전자들의 발현을 연구하기 위하여, B. lentimorbus WJ5의 방사선 유도 돌연변이체에서 발현되는 유전자를 DNA microarray로 동시에 탐색하였다. DNA microarray는 B. lentimorbus WJ5 genome을 무작위로 절단하여 2,000단편으로 구성하였으며, 감마선 (^(60)Co)으로 유도된 7돌연변이체의 발현을 정량적으로 관찰하였다. 클러스터 분석결과 발현된 408 유전자 중 27개가 감마선 유도 돌연변이체 모두에서 유의하게 발현이 증가되었다. 특히, 복구(mutL, mutM)에너지 대사 (acsA, sdhB, p하, yhjB, citB), protease(npr), 산화자극에 대한 환원 (HMM)관련 유전자들이 동시에 증가되었다. 이는 감마선 유도 돌연변이체들에서 자발적인 직/간접 복구 관련 유전자의 발현 증가는 방사선 노출 직후 보이는 stress response와는 다른 현상임을 나타내는 것으로 생각된다. To study the radiation related gene expression in mutants of Bacillus lentimorbus WJ5 induced by gamm radiation, the simultaneous gene expression was analyzed by DNA microarray. We constructed DNA chips including two thousand randomly digested genome spots of B. lentimorbus WJ5 and compared its quantitative aspect with seven mutants induced by gamma radiation (^(60)Co). From the cluster analysis of gene expression pattern, totally 408 genes were expressed and 27 genes were significantly upregulated by the gamma radiation in all mutants. Especially, genes involved in repair (mutL, mutM), energy metabolism (acsA, sdhB, pgk, yhjB, citB), protease (npr), and reduction response to oxidative stress (HMM) were simultaneously upregulated. It seems that the induction of the direct and/or indirect repair related genes in mutants induced by gamma radiation could be remarkably different from the adaptive responses against acute exposure to radiation.