Effect of Cr₂O₃ Content on Densification and Microstructural Evolution of the Al₂O₃-Polycrystalline and Its Correlation with Toughness

Seo, Mi-Young,Kim, Hee-Seung,Kim, Ik-Jin The Korean Ceramic Society 2006 한국세라믹학회지 Vol.43 No.8

The effects of $Cr_2O_3$ on the microstructural evolution and mechanical properties of $Al_2O_3$ polycrystalline were investigated. The microstructure of $Al_2O_3-Cr_2O_3$ composites (ruby) was carefully controlled in order to obtain dense and fine-grained ceramics, thereby improving their properties and reliability with respect to numerous applications related to semiconductor bonding technology. Ruby composites were produced by Ceramic Injection Molding (CIM) technology. Room temperature strength, hardness, Young's modulus and toughness were determined, as well as surface strengthening induced by thermal treatment and production of a fine-grained homogenous microstructure.

천식 환자와 정상인에 있어서의 Extracellular Phospholipase A_2의 활성도

서영의,김능수,이종명 慶北大學校 醫科大學 1992 慶北醫大誌 Vol.33 No.3

Extracellular PLA_2는 arachidonic acid cascade에 작용하는 효소로서 다양한 세포들에서 분비되며, 염증반응을 비롯한 여러가지 질환에 관여함이 알려져있다. 저자들은 기관지 천식과 PLA_2의 관계를 알아보기 위해 천식 환자들과 정상 대조군의혈청과 소변에서 PLA_2 활성도를 측정하고 폐기능 악화에 따른 천식정도, 혈청 IgE치 및 말초혈액 호산구 수와의 관계를 조사하였다. 정상 대조군에 비하여 천식 환자군에서 혈청 및 소변의 PLA_2 활성도가 유의하게 증가되어 있었으나(P<0.01, p<0.05) 혈청 PLA_2 활성도는 폐기능 정도와는 비례하지 않았다. 또한 혈청 PLA_2 활성도와 혈청 IgE치나 말초 혈액 호산구 수 사이에는 상관관계가 없었다. 이상의 결과로 볼 때 PLA_2는 기관지 천식의 병리 기전에 관여할 것으로 사료되나 혈청 PLA_2 활성도가 천식정도를 반영하지는 않는 것으로 보여진다. Extracellular phospholipase A_2(PLA_2) is known to be secreted by the mononucteocytes, granukxytes and chondrocytes in the joint, and it is also reported that this enzyme is increased in inflammatory conditions, such as acute pancreatitis, sepsis, ARDS and arthritis. To evaluate the changes of PLA_2 in the asthmatics the authors measured extracellular PLA_2 of asthmatics and healthy individuals in their serum and urine. In 84 normal controls, the levels of PLA_2 activity in serum and urine were 177.26±130.68 U/㎖ and 127.56±87.04 U/㎖, respectively. There was significant difference between male and female groups in serum and urine. In 51 asthmatics, the levels of PLA_2 activity in serum and urine were 739.10±454.52 U/㎖ and 292.50±154.49 U/㎖, respectively. These were significantly higher than those of healthy controls in both serum and urine. No significant correlation was found between serum PLA_2 activity and peripheral blood eosinophil count and there was no significant difference in serum PLA_2 activity between symptomatic asthmatics and asymptomatic asthmatics. However the level of serum PLA_2 activity in asymptomatic asthmatics was still higher than that of healthy controls. Receiving steroids seems to make no difference in serum PLA_2 activity in asymptomatic asthmatics.

기(氣)수련이 정신건강 프로파일에 미치는 효과

정영자,정현익,이명수,서채문 한국스포츠리서치 2003 한국 스포츠 리서치 Vol.20 No.1

This cross-sectional investigation evaluated the trend of psychological changes by Qi-training using a self-report inventory of emotional distress, Symptom Check List-90-Revision (SCL-90-R). Forty-one normal healthy subjects (mean age: 21.0±5.4) and one hundred-twenty-three Qi-trainees (divided into three groups, primary, middle and high level) participated in this study. Primary level group has received 1-4 months Qi-training (mean age: 22.0±7.8, n = 41); middle level group has 5-12 months Qi-training (mean age: 20.0±7.8, n = 41); and high level group has more than 1 year Qi-training (mean age: 22.7± 6.7, n = 41). Our results show that all of psychologucal symptom scales of Qi-trainees over lyear were significantly lower scores compared to controls. In addition, high level group had lower global indexes scores than control. A significant negative correlation was found between the Qi-training period and all SCL-90-R subscales except phobic anxiety. These results suggest that Qi-training is effective in protection as well as reduction of psychological symptomatology.

市販 睡眠劑의 LD_50 測定

金英善,崔峯子,徐益子 梨花女子大學校 藥學硏究所 1962 梨花藥學硏究 Vol.- No.3

淸熱藥類의 免疫藥理學的 考察(Ⅲ)

張成翼,徐榮培 대전대학교 한의학연구소 2001 혜화의학회지 Vol.10 No.1

In the result of investigating traditional chinese medical literatures to understand definite immunopharmacologic effects of drugs for clearing away heat and detoxicating such as Ampelopsis Radix, Rhapontici Radix, Cremastrae Appendiculatae Tuber, Rhaseoli Radiati Semen, Potentillae Discoloris Herba, Potentillae Chinensis Herba, Chrysanthemi Indici Flos, Lonicerae Caulis, we could reach conclusions as follows: 1. Rhapontici Radix, Chrysanthemi Indici Flos can increase voracity of leukocytes, macrophages and increase to produce IL-2 by splenocytes. 2. Potentillae Chinensis Herba, Chrysanthemi Indicici Flos, Lonicerae Caulis can inhibit activities of B lymphocytes and have anti-inflammatory effects. 3. Drugs for clearing away heat and detoxicating almost have antibiotic, anti-inflammatory effects, and so can be applied to many inflammatory immune diseaese. 4. Drugs for clearing away heat and detoxicating also have antifebrile, diuretic, detoxicating effects. Above results indicates that Drugs for clearing away heat and detoxicating have immunosupprissive effect, so that can be applied to many inflammatory immune diseases.

섬유판에서 음향방출원의 위치표정

박익근,김용권,윤종학,노승남,서성원 한국공작기계학회 2003 한국공작기계학회 추계학술대회논문집 Vol.2003 No.-

음향방출 신호를 이용하여 목재 섬유판(fiberboards)의 위치표정의 유용성 유무를 실험적으로 검증하였다. 위치표정의 정확도를 향상하기 위해 신호처리 방법중의 하나인 웨이블릿 변환 디노이징 기법을 활용하여 저주파수인 대칭모드(굽힘파)를 활용하고, 고주파수인 비대칭 모드(팽창파)룰 제거하여 신호를 재구성함으로써 섬유판의 위치표정시 문턱값 통과방법을 사용할 때 발생하는 도달시간차를 최소화 할 수 있음을 확인하였다. 디노이징 기법을 활용한 섬유판의 위치 표정과 굽힘강도에 대한 사상총수를 기초로 하여 목재 구조물 및 문화재의 건전성을 평가 할 수 있을 것으로 기대된다.

Densification and Thermo-Mechanical Properties of Al₂O₃-ZrO₂(Y₂O₃) Composites

Kim, Hee-Seung,Seo, Mi-Young,Kim, Ik-Jin The Korean Ceramic Society 2006 한국세라믹학회지 Vol.43 No.9

The microstructure of $ZrO_2$ toughened $Al_2O_3$ ceramics was carefully controlled so as to obtain dense and fine-grained ceramics, thereby improving the properties and reliability of the ceramics for capillary applications in semiconductor bonding technology. $Al_2O_3-ZrO_2(Y_2O_3)$ composite was produced via Ceramic Injection Molding (CIM) technology, followed by Sinter-HIP process. Room temperature strength, hardness, Young's modulus, thermal expansion coefficient and toughness were determined, as well as surface strengthening induced by the fine grained homogenous microstructure and the thermal treatment. The changes in alumina/zirconia grain size, sintering condition and HIP treatment were found to be correlated.

기관지천식 환자에서 Furosemide, Disodium cromoglycate 및 Heparin 흡입이 고장액 식염수 기관지유발검사에 미치는 영향

강천일,현상훈,남언정,김건우,윤종수,서영익,이종명,김능수 慶北大學校 醫科大學 1996 慶北醫大誌 Vol.37 No.3

목적 : 기관지천식 환자에서 고장액 식염수의 흡입은 기도수축을 유발할 수 있으며 이는 운동유발성 천식반응과 밀접한 관계가 있는 것으로 알려져 있다. 저자들은 알레르겐 흡입이나 운동에 의해 유발되는 천식에 예방효과가 있는 것으로 알려진 disodium cromoglycate(DSCG), furosemide 및 heparin 흡입이 4.5% NaCl 기관지유발검사(BPT)에 미치는 영향을 조사하였다. 대상 및 방법 : 4.5% NaCl BPT에서 양성반응을 보이는 기관지천식 환자 13명을 대상으로 하였으며 사용된 약물은 furosemide 40㎎, DSCG 40㎎ 및 heparin 1,000μ/㎏이었다. 먼저baseline 4.5% NaCl BPT를 시행한 다음 이들 약물로 전처치후 다시 4.5% NaCl BPT를 시행하여 약물의 효과를 관찰하였다. 결과 : Furosemide 40㎎, DSCG 40㎎및 heparin 1,000μ/㎏의 흡입 전처치는 고장액 식염수에 의한 기도수축 반응에 뚜렷한 예방효과를 보였다. Furosemide와 DSCG로 전처치한 군(n=6)에서 이들의 기도수축 방어율은 각각 100.6±6.6%, 91.1±17.2%였으며 furosemide와 heparin으로 전처치한 군(n=7)에서는 각각 58.7±29.2%, 59.0±51.1%로서 각 군에서 이들 약제간의 방어율에는 유의한 차이가 없었다. 결론 : Furosemide(40㎎), DSCG(40㎎) 및 heparin(1000μ/㎏)의 흡입 전처치는 고장액 식염수에 의한 기도수축 반응에 뚜렷한 예방효과를 보였으며, 적어도 이 용량에서 기도수축 예방 정도에는 유의한 차이가 없음을 알 수 있었다. Background: Hypertonic saline (4.5% NaCl) inhalation is known to induce broncho-constriction by affecting mast cell, epithelial cell and vagal afferent pathway in some asthmatics. Disodium cromoglycate (DSCG) is known to have a preventive effect on allergic asthma and exercise induced asthma, and recently it was reported that furosemide and heparin had similar effect. The purpose of this study was to evaluate the effects of furosemide, DSCG and heparin on hypertonic saline provocation test in asthmatics. Methods: Thirteen asthmatics with a positive response to hypertonic saline challenge were enrolled. Hypertonic saline and test drugs were generated by ultrasonic nebulizer. After taking baseline 4.5% NaCl challenge, subjects were rechallenged with 4.5% NaCl after inhalation of furosemide 40㎎, DSCG 40㎎ or heparin 1,000μ/㎏. Results: 1. There was a significant positive relationship between PC_20-methacholine and PTM-4.5% NaCl(r=0.5575, p = 0.024). 2. Furosemide, DSCG and heparin had no direct bronchodilating effects. 3. Premedication of furosemide and DSCG(n=6) showed significant protective effects on 4.5% NaCl induced broncho-constriction. The average protection rate were 100.6±6.6% and 91.1±17.2%, respectively. 4. Premedication of furosemide and heparin(n=7) showed significant protective effects on 4.5% NaCl induced broncho-constriction. The average protection rate were 58.7±29.2% and 59.0±51.1%. respectively. Conclusions: Furosemide(40㎎), DSCG(40㎎) and heparin(1.000μ/㎏) had significant protective effects on hypertonic saline induced broncho-constriction in asthmatics, and there were no significant differences in their potency of protection rate.

Hybridized porous structure of Al alloy by surface modification of pores

Seo, Young Ik,Kim, Young Moon,Lee, Young Jung,Kim, Se Hoon,Kim, Dae-Gun,Lee, Kyu Hwan,Kim, Young Do Springer-Verlag 2009 Journal of porous materials Vol.16 No.6

폐가축사체의 재활용을 위한 최적 알칼리분해 조건 구명

서영진(Young Jin Seo),서동철(Dong Cheol Seo),최익원(Ik Won Choi),성환후(Hwan Hoo Sung),허태영(Tai Young Hur),유지영(Ji Young Yoo),이영준(Young Joon Lee),허종수(Jong Soo Heo),강석진(Seok Jin Kang),조주식(Ju Sik Cho) 한국토양비료학회 2011 한국토양비료학회 학술발표회 초록집 Vol.2011 No.10