Examining the influencing factors of digital transformation using TOE and innovation diffusion theory : Empirical evidence from Chinese Enterprises

You Fu,Young-Chan Lee 한국경영정보학회 2020 한국경영정보학회 학술대회논문집 Vol.2020 No.12

Investigating determinants of digital transformation: Empirical evidence from Chinese companies

You Fu,Young-Chan Lee(이영찬) 한국아시아학회 2021 아시아연구 Vol.24 No.3

디지털 기술의 급속한 발전과 COVID-19 대유행으로 인해 기업은 전례 없는 영향과 도전에 직면해 있으며 디지털 전환의 필요성에 대한 인식이 강화되었다. 따라서 기업의 경쟁력 제고를 위한 디지털 전환 전략 수립이 시급한 상황이라고 할 수 있다. 본 연구는 TOE(기술, 조직, 환경) 프레임워크를 사용하여 중국 기업의 디지털 전환 결정요인을 실증적으로 조사하였다. 구체적으로, 313개 기업(관리자)을 대상으로 설문조사를 실시하고 기술, 조직, 환경 측면에서의 결정요인이 디지털 전환에 어떠한 영향을 미치는지에 관한 가설을 검증하였다. 분석 결과 대부분의 결정요인(복잡성, 호환성, 시행 가능성, 자원 준비성, 관리 지원, 경쟁 압력, 사회발전추세 압력)은 디지털 전환에 긍정적인 영향을 미치는 것으로 나타났다. 복잡성은 디지털 전환에 부정적인 영향을 미치며, 정부 지원은 디지털 전환에 유의한 영향을 미치지 않는 것으로 조사되었다. 본 연구는 기업들이 디지털 전환을 채택하는데 있어 실무적인 시사점을 제공할 뿐만 아니라 디지털 전환에 관한 향후 심층적인 연구를 수행하는데 유용한 학술적 시사점을 갖는다. Due to the rapid development of digital technology and the COVID-19 pandemic, companies have been confronted with unprecedented impacts and challenges, strengthening their awareness of the necessity of digital transformation (DT). Hence, it is urgent to establish a DT strategy to enhance the competitive advantage of companies. This study explores DT’s determinants of Chinese companies using TOE (technology, organization, environment) framework. We surveyed 313 companies (managers) and tested the hypotheses to serve the research purpose. According to the results, most of the determinants (compatibility, trialability, resource readiness, management support, competitive pressure, and bandwagon pressure) positively impact DT adoption. However, complexity has a negative impact on that. Furthermore, the relationship between relative advantage, government support, and DT adoption has not been supported. We expect that this paper provides a valuable practical reference for companies to adopt DT and put forward future research directions to promote a more in-depth study on the DT field.

Research on Rapid Detection Method of Pipeline Leakage Based on The Transient Flow Method

You Fu,Biao Chen 한국유체기계학회 2023 International journal of fluid machinery and syste Vol.16 No.2

This paper presents a numerical simulation of a leaking pipeline and verifies the method's applicability using existing experimental data. The method involves generating reflected waves at the leak point by using pressure waves generated by fast valve closure, which causes aberrations in the pressure signal at the valve. The different times of aberration at different leak locations can be used to determine the location of the leak. Furthermore, the time domain information of the pressure signal is refined using the wavelet transform method to capture sudden changes in the pressure signal, which improves the accuracy of the leakage position. This method was tested for different leak locations, sizes, and pipeline wave speed conditions, resulting in accurate detection with an error of less than 1%. When there are multiple leak locations in the pipeline system, the method has a high degree of recognition of the existence of multiple leak locations and can accurately detect the location of each leak. Additionally, the effect of different valve closing times on the pressure waveform of pipeline leaks was studied, demonstrating that slow valve closure can detect the occurrence of a leak in the pipeline, while fast valve closure can be used to locate the leak.

Research on Rapid Detection Method of Pipe Blockage Based on The Transient Flow Method

You Fu,Biao Chen 한국유체기계학회 2023 International journal of fluid machinery and syste Vol.16 No.4

This paper presents a numerical simulation of a blocked pipeline and verifies the method’s applicability using existing experimental data. Wavelet analysis analyzes pressure signals of blockage types, lengths, rates, and locations inside the horizontal pipeline. A method is obtained for rapidly calculating the blockage location, length, and rate based on pressure wave reflection and transmission principles. The average error for blockage location detection using this method is 0.36%, while the error for blockage length detection is 1.47% and for blockage rate detection is 1.24%. The reasons that affect detection accuracy are given. Additionally, the pressure signals of two unique blockage models are analyzed. Combining the calculation results of multiple blockage locations and different blockage shapes shows that this method is suitable for detecting various blockage forms. The method’s applicability is also investigated when multiple blockages exist in the piping system. It is concluded that the method can only detect the blockage at the nearest position of the valve when there are multiple blockage locations in the piping

An Energy-Efficient Dense PicoStation Deployment and Power Control Strategy for Heterogeneous Networks

You Fu,Zesong Fei,Niwei Wang,Chengwen Xing,Lei Wan 한국산학기술학회 2013 SmartCR Vol.3 No.1

Deploying PicoStations in traditional Macro-cellular networks, especially in hot-spot areas, is a promising strategy to boost system throughput and enhance indoor coverage. However, PicoStations’ introduction brings some new problems, such as severe interference and energy consumption, which may result in performance degradation. In order to improve energy efficiency, throughput fairness and PicoStation coverage, a practical energy-efficient dense PicoStation deployment and power control algorithm is proposed. The proposed scheme maximizes both the number of active PicoStations that can achieve the required capacity and the sum cell capacity under individual capacity constraints in two steps. Finally, simulation results demonstrate that the proposed algorithm outperforms the traditional cell capacity maximum scheme in terms of user fairness and energy saving.

Flexural behaviour of Steel Timber Composite (STC) beams

Ruyuan Yang,Haitao Li,Rodolfo Lorenzo,Youfu Sun,Mahmud Ashraf 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.41 No.2

Structural performance of a new type of lightweight steel-timber composite (STC) beam has been investigated by conducting four-point bending tests on 21 specimens. This paper presents key findings on its structural performance parameters such as failure modes, load-deflection response, load-slip response, load-strain response, and the ultimate bending capacity by grouping 21 specimens into 7 subgroups based on various geometric characteristics. In the proposed STC beams, glulam slabs were connected to the steel beams using high-strength bolts, and the effect of different thickness and width of glulam slabs on the structural behaviour of STC beams were carefully investigated. In addition, the effective bending stiffness, deflection, and bending capacity of the STC beams were theoretically calculated based on elastic theory and compared with experimental values. For all considered specimens, timber slabs and steel beams showed good composite action. Increasing the thickness and width of the timber slabs can effectively limit the lateral deformation of the specimens, improve the bending capacity of the specimens, and provides a secant stiffness to the STC beams. It was observed that for the whole cross section of STC beams, the plane section assumption is not applicable, but the strains on timber and steel seemed to satisfy the plane section assumption individually. γ (Gamma) method has been observed to better reflect the deformation capacity of STC beams. Analytical equations were derived to predict the elastic bending capacity of STC beams, and comparison between theoretical and experimental values showed good agreement.

5-Formylhonokiol exerts anti-angiogenesis activity $via$ inactivating the ERK signaling pathway

Zhu, Wei,Fu, Afu,Hu, Jia,Wang, Tianen,Luo, Youfu,Peng, Ming,Ma, Yinghua,Wei, Yuquan,Chen, Lijuan Korean Society for Biochemistry and Molecular Bion 2011 Experimental and molecular medicine Vol.43 No.3

Our previous report has demonstrated that 5-formylhonokiol (FH), a derivative of honokiol (HK), exerts more potent anti-proliferative activities than honokiol in several tumor cell lines. In present study, we first explored the antiangiogenic activities of 5-formylhonokiol on proliferation, migration and tube formation of human umbilical vein endothelial cells (HUVECs) for the first time $in$ $vitro$. Then we investigated the $in$ $vivo$ antiangiogenic effect of 5-formylhonokiol on zebrafish angiogenesis model. In order to clarify the underlying molecular mechanism of 5-formylhonokiol, we investigated the signaling pathway involved in controlling the angiogenesis process by western blotting assay. Wound-healing results showed that 5-formylhonokiol significantly and dose-dependently inhibited migration of cultured human umbilical vein enthothelial cells. The invasiveness of HUVEC cells was also effectively suppressed at a low concentration of 5-formylhonokiol in the transwell assay. Further F-actin imaging revealed that inhibitory effect of 5-formylhonokiol on invasion may partly contribute to the disruption of assembling stress fiber. Tube formation assay, which is associated with endothelial cells migration, further confirmed the anti-angiogenesis effect of 5-formylhonokiol. In $in$ $vivo$ zebrafish angiogenesis model, we found that 5-formylhonokiol dose-dependently inhibited angiogenesis. Furthermore, western blotting showed that 5-formylhonokiol significantly down-regulated extracellular signal-regulated kinase (ERK) expression and inhibited the phosphorylation of ERK but not affecting the total protein kinase B (Akt) expression and related phosphorylation, suggesting that 5-formylhonokiol might exert anti-angiogenesis capacity $via$ down-regulation of the ERK signal pathway. Taken together, these data suggested that 5-formylhonokiol might be a viable drug candidate in antiangiogenesis and anticancer therapies.

Facile Formation of a Benzopyrane-Fused [28]Hexaphyrin That Exhibits Distinct Möbius Aromaticity

Tokuji, Sumito,Shin, Jae-Yoon,Kim, Kil Suk,Lim, Jong Min,Youfu, Katsuyuki,Saito, Shohei,Kim, Dongho,Osuka, Atsuhiro American Chemical Society 2009 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.131 No.21

<P>A benzopyrane-fused [28]hexaphyrin, 2, was prepared by simple heating of [26]hexaphyrin 1 in acetic acid. Fused [28]hexaphyrin 2 features a molecular twist, a distinct diatropic ring current, a large HOMA value, a large negative NICS value, and a large two-photon absorption (TPA) cross section even at room temperature, all of which support the Möbius aromaticity of 2. To the best of our knowledge, 2 is the first macrocycle that acquires distinct Möbius aromaticity without any assistance from metal coordination, temperature control, or protonation.</P>

5-Formylhonokiol exerts anti-angiogenesis activity via inactivating the ERK signaling pathway

Wei Zhu,Lijuan Chen,Afu Fu,Jia Hu,Tianen Wang,Youfu Luo,Ming Peng,Yinghua Ma,Yuquan Wei 생화학분자생물학회 2011 Experimental and molecular medicine Vol.43 No.3

Our previous report has demonstrated that 5-formylhonokiol (FH), a derivative of honokiol (HK), exerts more potent anti-proliferative activities than honokiol in several tumor cell lines. In present study, we first explored the antiangiogenic activities of 5-formylhonokiol on proliferation, migration and tube formation of human umbilical vein endothelial cells (HUVECs) for the first time in vitro. Then we investigated the in vivo antiangiogenic effect of 5-formylhonokiol on zebrafish angiogenesis model. In order to clarify the underlying molecular mechanism of 5-formylhonokiol, we investigated the signaling pathway involved in controlling the angiogenesis process by western blotting assay. Wound-healing results showed that 5-formylhonokiol significantly and dose-dependently inhibited migration of cultured human umbilical vein enthothelial cells. The invasiveness of HUVEC cells was also effectively suppressed at a low concentration of 5-formylhonokiol in the transwell assay. Further F-actin imaging revealed that inhibitory effect of 5-formylhonokiol on invasion may partly contribute to the disruption of assembling stress fiber. Tube formation assay, which is associated with endothelial cells migration,further confirmed the anti-angiogenesis effect of 5-formylhonokiol. In in vivo zebrafish angiogenesis model, we found that 5-formylhonokiol dose-dependently inhibited angiogenesis. Furthermore, western blotting showed that 5-formylhonokiol significantly down-regulated extracellular signal-regulated kinase (ERK) expression and inhibited the phosphorylation of ERK but not affecting the total protein kinase B (Akt)expression and related phosphorylation, suggesting that 5-formylhonokiol might exert anti-angiogenesis capacity via down-regulation of the ERK signal pathway. Taken together, these data suggested that 5-formylhonokiol might be a viable drug candidate in antiangiogenesis and anticancer therapies.

The Bacterial Alarmone (p)ppGpp Activates the Type III Secretion System in <i>Erwinia amylovora</i>

Ancona, Veronica,Lee, Jae Hoon,Chatnaparat, Tiyakhon,Oh, Jinrok,Hong, Jong-In,Zhao, Youfu American Society for Microbiology 2015 Journal of Bacteriology Vol.197 No.8

<P>The hypersensitive response and pathogenicity (<I>hrp</I>) type III secretion system (T3SS) is a key pathogenicity factor in <I>Erwinia amylovora</I>. Previous studies have demonstrated that the T3SS in <I>E. amylovora</I> is transcriptionally regulated by a sigma factor cascade. In this study, the role of the bacterial alarmone ppGpp in activating the T3SS and virulence of <I>E. amylovora</I> was investigated using ppGpp mutants generated by Red recombinase cloning. The virulence of a ppGpp-deficient mutant (ppGpp<SUP>0</SUP>) as well as a <I>dksA</I> mutant of <I>E. amylovora</I> was completely impaired, and bacterial growth was significantly reduced, suggesting that ppGpp is required for full virulence of <I>E. amylovora</I>. Expression of T3SS genes was greatly downregulated in the ppGpp<SUP>0</SUP> and <I>dksA</I> mutants. Western blotting showed that accumulations of the HrpA protein in the ppGpp<SUP>0</SUP> and <I>dksA</I> mutants were about 10 and 4%, respectively, of that in the wild-type strain. Furthermore, higher levels of ppGpp resulted in a reduced cell size of <I>E. amylovora</I>. Moreover, serine hydroxamate and α-methylglucoside, which induce amino acid and carbon starvation, respectively, activated <I>hrpA</I> and <I>hrpL</I> promoter activities in <I>hrp</I>-inducing minimal medium. These results demonstrated that ppGpp and DksA play central roles in <I>E. amylovora</I> virulence and indicated that <I>E. amylovora</I> utilizes ppGpp as an internal messenger to sense environmental/nutritional stimuli for regulation of the T3SS and virulence. </P><P><B>IMPORTANCE</B> The type III secretion system (T3SS) is a key pathogenicity factor in Gram-negative bacteria. Fully elucidating how the T3SS is activated is crucial for comprehensively understanding the function of the T3SS, bacterial pathogenesis, and survival under stress conditions. In this study, we present the first evidence that the bacterial alarmone ppGpp-mediated stringent response activates the T3SS through a sigma factor cascade, indicating that ppGpp acts as an internal messenger to sense environmental/nutritional stimuli for the regulation of the T3SS and virulence in plant-pathogenic bacteria. Furthermore, the recovery of an <I>spoT</I> null mutant, which displayed very unique phenotypes, suggested that small proteins containing a single ppGpp hydrolase domain are functional.</P>