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팽유청 ( You Qing Peng ),윤미라 ( Mi Ra Yoon ) 대한무용학회 2013 대한무용학회논문집 Vol.71 No.2
As the study result, it was found that the bara dances (뇨발舞) in Korea and China are a part of religious ceremony, in which people worship Buddha and console the souls of the dead during Buddhist ceremony. Both bara dances (뇨발舞) in Korea and China contain substantial amount of religious culture content. However, bara dance (뇨발舞) became a performance art now and the bara dances (뇨발舞) in Korea and China have certain differences. Modern bara dances (뇨발舞) in Korea and China have its own characteristic, which implies that two arts from same root were culturally transformed in accordance with aesthetic requirement in the culture of Korea and China.
한,중「포구락(抛球樂)」의 사적 전개에 나타난 변화양상에 관한 연구
팽유칭 ( You Qing Peng ),윤미라 ( Mi Ra Yoon ) 대한무용학회 2014 대한무용학회논문집 Vol.72 No.1
This study analyzed the development pattern of 「Paoqiule (抛球樂)」 among the royal court performances during the Sui (隋) period in China and the historical development of it after it had been introduced to Korea. The purpose of this study is suggesting the changing pattern in the historical development of 「Paoqiule (抛球樂)」 developed in Korea and China. 「Paoqiule (抛球樂)」 is a representative royal court dance, which had started as a royal court performance, and maintained the character as an entertainment while keeping the format of royal court dance.
Han, Shu-Jing,Guo, Qing-Qing,Wang, Ting,Wang, You-Xin,Zhang, Yu-Xiang,Liu, Fen,Luo, Yan-Xia,Zhang, Jie,Wang, You-Li,Yan, Yu-Xiang,Peng, Xiao-Xia,Ling, Rui,He, Yan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.10
Objective: Both estrogen receptors, ER alpha ($ER{\alpha}$) and ER beta ($ER{\beta}$), are expressed in 50-70% of breast cancer cases. The role of $ER{\alpha}$ as a prognostic marker in breast cancer has been well established as its expression is negative correlated with tumor size and lymph node metastasis. $ER{\beta}$ is also a favorable prognostic predictor although this is less well documented than for $ER{\alpha}$. Materials and Methods: To explore whether ERs independently or together might influence clinical outcome in breast cancer, the correlation between the ERs with the clinicopathological features was analyzed in 84 patients. Results: $ER{\alpha}$ expression negatively correlated with tumor stage (r=-0.246, p=0.028) and tended to be negatively correlated with lymph node status (r=-0.156, p=0.168) and tumor size (r=-0.246, p=0.099). Also, $ER{\beta}$ was negatively correlated with nodal status (r=-0.243, p=0.028), as was coexpression of $ER{\alpha}$ and $ER{\beta}$ (p=0.043, OR=0.194, 95% CI= 0.040-0.953). Conclusion: Coexpression of ERs might serve as an indicator of good prognosis in breast cancer patients.
Qingli Li,Lunxu Liu,Qiuyang Zhang,Sen Liu,Dongxia Ge,Zongbing You 대한암학회 2014 Cancer Research and Treatment Vol.46 No.3
PurposeInterleukin-17 (IL-17) is a proinflammatory cytokine that plays important roles ininflammation, autoimmunity, and cancer. The purpose of this study was to determineif IL-17 indirectly regulates macrophage differentiation through up-regulation ofcyclooxygenase-2 (COX-2) expression in the cancer cell lines. Materials and MethodsHuman cervical cancer HeLa, human lung cancer A549, and mouse prostate cancerMyc-CaP/CR cell lines were treated with recombinant IL-17; Western blot analysis,enzyme-linked immunosorbent assay, and quantitative real-time polymerase chainreaction analysis were utilized to examine the cellular responses. ResultsIL-17 up-regulated expression of COX-2 mRNA and protein in HeLa, A549, and Myc-CaP/CR cell lines. IL-17’s effects were mediated through nuclear factor-κB andERK1/2 signaling pathways as the inhibitors of these pathways could inhibit IL-17-induced COX-2 expression. The conditional medium obtained from the cancer cellscontained prostaglandin E2, the levels of which were increased by IL-17 treatment. When treated with the conditional medium, particularly with the IL-17-induced conditionalmedium, mouse RAW264.7 macrophages and human THP-1 monocytes expressedhigher levels of IL-10 (a marker of M2 macrophages) than inducible nitricoxide synthase or tumor necrosis factor α (markers of M1 macrophages). In contrast,when RAW264.7 and THP-1 cells were treated directly with IL-17, expression of thesemarker genes was not markedly changed. ConclusionThe results of this study suggest that IL-17 indirectly promotes M2 macrophagedifferentiation through stimulation of the COX-2/PGE2 pathway in the cancer cells,thus IL-17 plays an indirect role in regulating the tumor immune microenvironment.
Shi, Qing-Qiang,Zuo, Guo-Wei,Feng, Zi-Qiang,Zhao, Lv-Cui,Luo, Lian,You, Zhi-Mei,Li, Dang-Yang,Xia, Jing,Li, Jing,Chen, Di-Long Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.18
Purpose: To investigate the effect of deacetylase inhibitory trichostatin A (TSA) on anti HepG2 liver carcinoma cells and explore the underlying mechanisms. Materials and Methods: HepG2 cells exposed to different concentrations of TSA for 24, 48, or 72h were examined for cell growth inhibition using CCK8, changes in cell cycle distribution with flow cytometry, cell apoptosis with annexin V-FTIC/PI double staining, and cell morphology changes under an inverted microscope. Expression of ${\beta}$-catenin, HDAC1, HDAC3, H3K9, CyclinD1 and Bax proteins was tested by Western blotting. Gene expression for ${\beta}$-catenin, HDAC1and HDAC3 was tested by q-PCR. ${\beta}$-catenin and H3K9 proteins were also tested by immunofluorescence. Activity of Renilla luciferase (pTCF/LEF-luc) was assessed using the Luciferase Reporter Assay system reagent. The activity of total HDACs was detected with a HDACs colorimetric kit. Results: Exposure to TSA caused significant dose-and time-dependent inhibition of HepG2 cell proliferation (p<0.05) and resulted in increased cell percentages in G0/G1 and G2/M phases and decrease in the S phase. The apoptotic index in the control group was $6.22{\pm}0.25%$, which increased to $7.17{\pm}0.20%$ and $18.1{\pm}0.42%$ in the treatment group. Exposure to 250 and 500nmol/L TSA also caused cell morphology changes with numerous floating cells. Expression of ${\beta}$-catenin, H3K9and Bax proteins was significantly increased, expression levels of CyclinD1, HDAC1, HDAC3 were decreased. Expression of ${\beta}$-catenin at the genetic level was significantly increased, with no significant difference in HDAC1and HDAC3 genes. In the cytoplasm, expression of ${\beta}$-catenin fluorescence protein was not obvious changed and in the nucleus, small amounts of green fluorescence were observed. H3K9 fluorescence protein were increased. Expression levels of the transcription factor TCF werealso increased in HepG2 cells following induction by TSA, whikle the activity of total HDACs was decreased. Conclusions: TSA inhibits HDAC activity, promotes histone acetylation, and activates Wnt/${\beta}$-catenin signaling to inhibit proliferation of HepG2 cell, arrest cell cycling and induce apoptosis.
Yi-Qing Ni,You-Wu Wang,Wei-Yang Liao,Wei-Huan Chen 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.24 No.6
Dynamic displacement response of civil structures is an important index for in-construction and in-service structural condition assessment. However, accurately measuring the displacement of large-scale civil structures such as high-rise buildings still remains as a challenging task. In order to cope with this problem, a vision-based system with the use of industrial digital camera and image processing has been developed for long-distance, remote, and real-time monitoring of dynamic displacement of supertall structures. Instead of acquiring image signals, the proposed system traces only the coordinates of the target points, therefore enabling real-time monitoring and display of displacement responses in a relatively high sampling rate. This study addresses the in-situ experimental verification of the developed vision-based system on the Canton Tower of 600 m high. To facilitate the verification, a GPS system is used to calibrate/verify the structural displacement responses measured by the vision-based system. Meanwhile, an accelerometer deployed in the vicinity of the target point also provides frequency-domain information for comparison. Special attention has been given on understanding the influence of the surrounding light on the monitoring results. For this purpose, the experimental tests are conducted in daytime and nighttime through placing the vision-based system outside the tower (in a brilliant environment) and inside the tower (in a dark environment), respectively. The results indicate that the displacement response time histories monitored by the vision-based system not only match well with those acquired by the GPS receiver, but also have higher fidelity and are less noise-corrupted. In addition, the low-order modal frequencies of the building identified with use of the data obtained from the vision-based system are all in good agreement with those obtained from the accelerometer, the GPS receiver and an elaborate finite element model. Especially, the vision-based system placed at the bottom of the enclosed elevator shaft offers better monitoring data compared with the system placed outside the tower. Based on a wavelet filtering technique, the displacement response time histories obtained by the vision-based system are easily decomposed into two parts: a quasi-static ingredient primarily resulting from temperature variation and a dynamic component mainly caused by fluctuating wind load.