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      • SCIESCOPUS

        Compact size of a Wilkinson power divider using impedance coordinate tracking based on T‐shaped line

        Yoon, Ki‐,Cheol,Chung, Taishin,Kim, Kwang Gi,Yoo, Heon John Wiley Sons, Inc. 2019 MICROWAVE AND OPTICAL TECHNOLOGY LETTERS Vol.61 No.8

        <P><B>Abstract</B></P><P>This article presents the compact size of the Wilkinson power divider using T‐shaped line through the impedance coordinate tracking progress at Smith‐chart. After the series line impedance, electrical length, and stub impedance were calculated, the T‐shaped line was designed through the impedance coordinate tracking in the Smith‐chart. This reduced the entire size of the proposed power divider by an average of 4.81 times (79.2%) more than conventional structure. The experimental results of the <I>S</I><SUB>21</SUB>, <I>S</I><SUB>31</SUB>, and <I>S</I><SUB>11</SUB> are 3.06 dB, 3.08 dB, and 25.04 dB at center frequency of 2.318 GHz, respectively. The experimented <I>S</I>‐parameter difference between <I>S</I><SUB>21</SUB> and <I>S</I><SUB>31</SUB> is 3.0 dB. This proposed Wilkinson power divider can be applied to mobile communications and wireless medical communication systems.</P>

      • KCI등재

        근대 미학과 경건주의 - 바움가르텐의 『시론』 연구

        안윤기 ( An¸ Yoon-ki ) 한국동서철학회 2021 동서철학연구 Vol.- No.101

        이 연구의 목표는 근대 미학의 태동이 경건주의와 긴밀하게 관련되어 있음을 밝히는 것이다. 이를 위해 미학이 최초로 요청된 바움가르텐의 『시론』(1735)을 살펴보았다. 이 작품이 나온 시대적 배경으로 ‘라이프치히-취리히 논쟁’과 ‘베르트하임 성경 논란’을 고찰하면서, 이성을 과도하게 강조한 계몽주의 세력과 맞서 싸우는 것이 18세기 초엽 경건주의 진영의 최대 관심사였음을 보였다. 경건주의 세력의 중심도시가 독일 할레였는데, 이곳에서 바움가르텐은 성장했고 교수자격청구논문으로 『시론』을 제출했으므로, 이 논문에 경건주의의 영향이 반영되었으리라고 추정할 수 있다. 『시론』에서 바움가르텐은 시의 요건을 논하면서, 거기서 부각된 ‘감성적 인식’을 전담할 새로운 학문, ‘미학’이 필요함을 이야기했다. 여기서 발견되는 경건주의적 함축으로 (1) 감성적 인식 개념을 통해 인간의 인식능력을 제한한 점, (2) 아이스테시스 개념을 중용하여 진리와 인식 범위를 예술과 실천, 종교 영역으로까지 확대한 점, (3) 이성이 아닌 정서에서 완전성을 찾으려 했다는 점 등이 있다. The aim of this paper is to point out that the birth of Modern Aesthetics has a innate relationship with Pietism. For that it examines Baumgarten’s Reflexions on Poetry (1735), in which the Aesthetics was claimed as an academic discipline for the first time. This paper begins with introducing the Leipzig-Zurich debate and the scandal of Wertheim-Bible, which built the historical background of that work by Baumgarten. Thereby it turns out that the chief concern of the Pietists in the early 18th century is to refute the ideas of the Enlightenment. These efforts to find the Pietistic influences in the Reflexions on Poetry are supported by the fact that Baumgarten was raised, studied, and submitted this work as habilitation in Halle, the stronghold of the Pietists. Discussing the requirements of the poetry in the Reflexions on Poetry, Baumgarten demands a new discipline for sensate cognition. Here are found the following points of the Pietistic influences in this work: (1) to set a limit to human cognitive abilities through the concept of ‘sensate cognition’; (2) to enlarge the scope of truth and cognition to the areas of art, the practical and religion with the term ‘aisthesis’; (3) to place the concept ‘perfection’ not in rationality, but in affects.

      • KCI등재

        A Comprehensive Analysis of 5-Year Outcomes in Patients with Cancer Admitted to Intensive Care Units

        Yoonki Hong,Kim Woo Jin,Hong Ji Young,Jeong Yun-jeong,Park Jinkyeong 대한결핵및호흡기학회 2022 Tuberculosis and Respiratory Diseases Vol.85 No.2

        Background: The aim of this study was to evaluate the long-term (5-year) clinical outcomes of patients who received intensive care unit (ICU) treatment using Korean nationwide data.Methods: All patients aged >18 years with ICU admission according to Korean claims data from January 2008 to December 2010 were enrolled. These enrolled patients were followed up until December 2015. The primary outcome was ICU mortality.Results: Among all critically ill patients admitted to the ICU (n=323,765), patients with cancer showed higher ICU mortality (18.6%) than those without cancer (13.2%, p<0.001). However, there was no significant difference in ICU mortality at day 28 among patients without cancer (14.5%) and those with cancer (lung cancer or hematologic malignancies) (14.3%). Compared to patients without cancer, hazard ratios of those with cancer for ICU mortality at 5 years were: 1.90 (1.87–1.94) for lung cancer; 1.44 (1.43–1.46) for other solid cancers; and 3.05 (2.95–3.16) for hematologic malignancies.Conclusion: This study showed that the long-term survival rate of patients with cancer was significantly worse than that of general critically ill patients. However, short term outcomes of critically ill patients with cancer were not significantly different from those of general patients, except for those with lung cancer or hematologic malignancies.

      • SCOPUSKCI등재

        A Comprehensive Analysis of 5-Year Outcomes in Patients with Cancer Admitted to Intensive Care Units

        ( Yoonki Hong ),( Woo Jin Kim ),( Ji Young Hong ),( Yun-jeong Jeong ),( Jinkyeong Park ) 대한결핵 및 호흡기학회 2022 Tuberculosis and Respiratory Diseases Vol.85 No.2

        Background: The aim of this study was to evaluate the long-term (5-year) clinical outcomes of patients who received intensive care unit (ICU) treatment using Korean nationwide data. Methods: All patients aged >18 years with ICU admission according to Korean claims data from January 2008 to December 2010 were enrolled. These enrolled patients were followed up until December 2015. The primary outcome was ICU mortality. Results: Among all critically ill patients admitted to the ICU (n=323,765), patients with cancer showed higher ICU mortality (18.6%) than those without cancer (13.2%, p<0.001). However, there was no significant difference in ICU mortality at day 28 among patients without cancer (14.5%) and those with cancer (lung cancer or hematologic malignancies) (14.3%). Compared to patients without cancer, hazard ratios of those with cancer for ICU mortality at 5 years were: 1.90 (1.87-1.94) for lung cancer; 1.44 (1.43-1.46) for other solid cancers; and 3.05 (2.95-3.16) for hematologic malignancies. Conclusion: This study showed that the long-term survival rate of patients with cancer was significantly worse than that of general critically ill patients. However, short term outcomes of critically ill patients with cancer were not significantly different from those of general patients, except for those with lung cancer or hematologic malignancies.

      • Levels of vitamin D-associated cytokines distinguish between active and latent tuberculosis following a tuberculosis outbreak

        ( Yoonki Hong ),( Myung Goo Lee ),( Chang Youl Lee ),( Youlim Kim ),( Jeongwon Heo ),( Seon-sook Han ),( Seung-joon Lee ),( Woo Jin Kim ),( Ji Young Hong ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-

        Background: Vitamin D levels are associated with the extent of mycobactericidal activity. Interleukin (IL)-15 and IL-32 play roles in the vitamin D-mediated tuberculosis (TB) defense mechanism. Vitamin D induces IL-1β, which plays an important role in terms of resistance to TB. We evaluated whether the levels of vitamin D-related cytokines distinguished between those with active TB and latent TB infection (LTBI). Methods: In total, 26 healthy controls and 50 TB-infected patients (25 with active TB and 25 with LTBI following a TB outbreak in a high school) were enrolled. Plasma vitamin D, IL-15, IL-32, and IL-1β levels were measured via enzyme-linked immunosorbent assays. Mycobacterium tuberculosis-specific antigen-induced and unstimulated cytokine levels were measured in the supernatants of the QuantiFERON TB Gold-In-Tube (QFT-GIT) assay. Results: Vitamin D and plasma IL-15 levels were lower in patients with active TB than in LTBI subjects (vitamin D: 16.64 ng/mL vs. 21.6 ng/mL, P=0.031; IL-15: 148.9 pg/mL vs. 189.8 pg/mL, P=0.013). Plasma vitamin D levels correlated with the plasma levels of IL-15 and IL-1β. In addition, the plasma vitamin D levels correlated positively with the level of unstimulated IL-15 (IL-15nil) and negatively with that of TB antigen-stimulated IL-32 (IL-32TB) in QFT-GIT supernatants. Although the IL-15nil and IL-15TB levels were higher in LTBI subjects than patients with active TB, the IL-32nil and IL-32TB levels were higher in the latter patients. A combination of the IL-15nil and IL-32TB levels accurately predicted 91.3% of active TB patients and latent subjects, with an area under the curve of 0.964. Conclusions: Together, our preliminary data suggest that the levels of the vitamin D-related cytokines IL-15 and IL-32 may be used to create a biomarker distinguishing between active TB and LTBI.

      • KCI등재후보

        Subcutaneous Emphysema and Pneumothorax Occurred during Patient Transfer to Intensive Care Unit: A Case Report

        Yoonki Lee,Won Young Kim Korean Society of Critical Care Medicine 2004 Acute and Critical Care Vol.19 No.1

        A 48 years old female patient was scheduled for emergency surgery due to bleeding after intracerebral aneurysmal clipping under general anesthesia. Previously checked chest X-ray taken just a few hours before surgery showed no abnormal finding and she didn't show any sign of pneumothorax or hemothorax including dyspnea, tachypnea or cyanosis. Surgery was uneventful. After the completion of surgery, patient was transferred to the neurosurgical intensive care unit with intubation. During transfer, patient showed bucking and signs of subcutaneous emphysema around chest, shoulder and face. Oxygen saturation was low when she admitted to the neurosurgical intensive care unit, so the ventilator care was started. The patient's oxygenation were getting worse progressively, so we checked chest AP several times and one of the chest X-ray taken at that time revealed no vascular and lung marking on the left lung field suggesting pneumothorax. Emergency chest tube drainage was performed. She recovered dramatically and three days later, ches X-ray showed the complete resorption of the pneumothorax.

      • KCI등재

        Perceived Recovery Time from Common Cold as a Possible Indicator of Physical Resilience

        Yoonki Kim,Chang Won Won,Sunyoung Kim,Byung Sung Kim,Miji Kim,Eunjin Jeong,Jisoo Yang,Hyona Lee 대한노인병학회 2021 Annals of geriatric medicine and research Vol.25 No.3

        Background: Resilience refers to the ability to recover function after encounter with stressors. While psychological resilience refers to the ability to cope with psychological stress, physical resilience refers to functional restoration after biomedical challenges. However, there is no gold standard to assess physical resilience. Accordingly, we explored whether the perceived recovery time from common cold could be used to represent physical resilience. Methods: We analyzed data of individuals aged 72–86 years who had participated in the Korean Frailty and Aging Cohort Study in 2019. Among the 1,455 survey participants, 594 with asthma and chronic obstructive pulmonary disease and missing data were excluded. The remaining 861 participants were divided into three groups according to the number of days required for recovery from common cold (Group 1, 1–4 days; Group 2, 5–7 days; and Group 3, ≥8 days). The relationship between recovery time and psychological resilience scale (Brief Resilience Scale [BRS]) score, physical frailty (Fried’s physical frailty phenotype and the Korean Frailty Index for Primary Care [KFI-PC]), and frailty outcome was investigated. Results: Group 3 comprised individuals more likely to be women, sleep less, be less physically less active, fall more often, and have a low EuroQol visual analogue scale score. BRS scores differed significantly among the three groups (Group 1, 13.29; Group 2, 14.32; Group 3, 15.22; p<0.001). In multivariate analysis, post-hoc analysis with the Bonferroni method revealed significant differences in BRS between Groups 1–2 and Groups 1–3. However, the KFI-PC and number of falls did not differ significantly. Conclusions: Longer days of recovery from cold were associated with worse BRS scores. However, neither frailty nor the number of falls was related.

      • KCI등재

        Identification of lung cancer specific differentially methylated regions using genome-wide DNA methylation

        Yoonki Hong,Seok-Ho Hong,Yeon-Mok Oh,Seung-Ho Shin,Sun Shim Choi,Woo Jin Kim 대한독성 유전단백체 학회 2018 Molecular & cellular toxicology Vol.14 No.3

        Backgrounds: Many molecular biomarkers have been suggested for the diagnosis, prognosis, and treatment response of lung cancer, but their clinical availability remains limited. DNA methylation is one such promising biomarker because it is stable and easily detected. Methods: We conducted an epigenome-wide analysis using methyl binding domain (MBD) sequencing in tissues of lung cancer patients. Tumor and normal tissues were obtained from two patients who underwent surgery for non-small cell lung cancer. Results: HOXA5, HOXA9, and other related genes were associated with the CGI-located DMRs in Patient 1, whereas the SSTR5 gene was found to be associated with the CGI-located DMRs in Patient 2. Interestingly, these DMR genes were mapped in the physical interaction networks that included previously known nonsmall cell lung cancer genes. Conclusion: This genome-wide DNA methylation study showed an association between newly identified DMRs in CpG island promoter regions and previously known target genes for lung cancer.

      • SCOPUSKCI등재

        Contributors of the Severity of Airflow Limitation in COPD Patients

        ( Yoonki Hong ),( Eun Jin Chae ),( Joon Beom Seo ),( Ji-Hyun Lee ),( Eun-Kyung Kim ),( Young Kyung Lee ),( Tae-Hyung Kim ),( Woo Jin Kim ),( Jin Hwa Lee ),( Sang-Min Lee ),( Sangyeub Lee ),( Seong Yon 대한결핵 및 호흡기학회 2012 Tuberculosis and Respiratory Diseases Vol.72 No.1

        Although airway obstruction in chronic obstructive pulmonary disease (COPD) is due to pathologic processes in both the airways and the lung parenchyma, the contribution of these processes, as well as other factors, have not yet been evaluated quantitatively. We therefore quantitatively evaluated the factors contributing to airflow limitation in patients with COPD. The 213 COPD patients were aged >45 years, had smoked >10 pack-years of cigarettes, and had a post-bronchodilator forced expiratory volume in one second (FEV1)/forced vital capacity (FVC) <0.7. All patients were evaluated by medical interviews, physical examination, spirometry, bronchodilator reversibility tests, lung volume, and 6-minute walk tests. In addition, volumetric computed tomography (CT) was performed to evaluate airway wall thickness, emphysema severity, and mean lung density ratio at full expiration and inspiration. Multiple linear regression analysis was performed to identify the variables independently associated with FEV1 - the index of the severity of airflow limitation. Multiple linear regression analysis showed that CT measurements of mean lung density ratio (standardized coefficient β=?0.46; p<0.001), emphysema severity (volume fraction of the lung less than ?950 HU at full inspiration; β=?0.24; p<0.001), and airway wall thickness (mean wall area %; β=?0.19, p=0.001), as well as current smoking status (β=?0.14; p=0.009) were independent contributors to FEV1. Mean lung density ratio, emphysema severity, and airway wall thickness evaluated by volumetric CT and smoking status could independently contribute to the severity of airflow limitation in patients with COPD.

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