급성전골수성백혈병에서 백혈구성분채집술에 이은 치명적인 뇌출혈 2예

오윤정,박소윤,김윤정,한동석,김현수,최진혁,남동기,임호영,김효철,주희재 아주대학교 의과학연구소 1998 아주의학 Vol.3 No.1

The aim of this study is to report 2 cases of acute promyelocytic leukemia who died from intracranial hemorrhage following leukapheresis and to provide proper preventive measures against hemorrhage following leukapheresis. From 1994 to 1997, a total of twenty-six patients with leukemia underwent leukapheresis to control hyperleukocytosis at Ajou University Hospital. Two patients with acute promyelocytic leukemia received all-trans retinoic acid but developed drug-induced hyperleukocytosis. Shortly after leukapheresis, they died from intracranial hemorrhage. The risk factors for fatal hemorrhage are thought to be coexisting disseminated intravascular coagulation(DIC), thrombocytopenia aggravated by leukapheresis, exacerbated coagulopathy related to mechanical trauma through leukapheresis and the excess use of citrate during leukapheresis. To reduce the risk of the bleeding associated with leukapheresis, it is necessary to replace platelet sufficiently before and after leukapheresis and to give calcium to correct coagulopathy induced by excess citrate which is used as anticoagulant as well as the correction of disseminated intravascular coagulation.

축구선수의 Detraining과 Retraining이 혈청지질 및 호르몬농도에 미치는 영향

정정화,박재현,채종훈,성혜련,황지인,윤미숙,노금선,윤종관,윤영학,노순덕,정경숙,박일규,김은희,박현태,박상갑 대한스포츠의학회 1999 대한스포츠의학회지 Vol.17 No.1

The purpose of this study was to investigate the effects of detraining and retraining on serum lipid and hormones in soccer players. Subjects were seven male high-school soccer players. V˙O_2max was determined for each subjects by administering a treadmill test(initial speed: 90m/min, grade: 5%, increasing speed per 3 min: 30m/min). Serum lipid(T-C, TG, HDL-C LDL-C) and hormones(epinephrine, norepinephrine, growth hormones, cortisol) were assayed pre and post detraining in 10, 20, 30 days after retraining. The repeated ANOVA was used to determine significant differences. The 0.05 level of significance was as critical level for the study. The results of the study were as follows: 1. V˙O_2max(ml/min) were 3576.3±204.2ml/min pre detraining, 3234.1±198.9 ml/min post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/min) were 3601.4±170.9 ml/min. There were significantly(p<.05) increased in retraining periods. 2. V˙O_2max(ml/kg/min) were significantly(p<.05) decreased from 62.3±2.9 ml/kg/min to 55.9±4.7 ml/kg/min in detraining. In 10, 20, 30 days after retraining, V˙O_2max(ml/kg/min) were 62.4±3.4ml/kg/min, 62.7±2.3ml.kg/min, 67.3±7.2ml/kg/min respectively. There were significantly(p<.05) increased in retraining periods. 3. T-C were significantly (p<.05) increased from 166.6±8.5mg/dl to 175.3±10.3 mg/dl in detraining. In 10, 20, 30 days after retraining, T-C were 160.1± 3.2mg/dl, 156.7±3.7mg/dl, 140.3±9.0mg/dl. There were significantly(p<.05) decreased in retraining periods. 4. HDL-C were 61.4±6.6mg/di pre detraining, 5.3±6.6mg/dl post detraining. There are significant(p<.05) difference between pre and post detraining. In 10, 20, 30 days after retraining, HDL-C were 56.9±7.1mg/dl, 56.4±9.2mg/dl, 57.7±9.1mg/dl respectively. There were no significant difference in retraining periods. 5. The hormones(epinephrine. norepinephrine, growth hormone, cortisol) were changed as same patterns. Epinephrine were 26.0±7.0[g/ml pre detraining, 24.6±3.2pg/ml post detraining. In 10, 20, 30 days after retraining, epinephrine were 26.9±5.6pg/ml, 30.6±6.2pg/ml, 29.4±5.6pg/ml respectively. There were no significant difference in retraining periods. In conclusion, HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were decreased, T-C, LDL-C and TG were increased in detraining. But HDL-C, epinephrine, norepinephrine, growth hormone and cortisol were increased, T-C, LDL-C and TG were decreased in retraining.

태권도 경기가 혈중대사산물에 미치는 영향

윤영학 한국스포츠리서치 2004 한국 스포츠 리서치 Vol.15 No.3

The purpose of this study was to investigate the distribution of VO₂max. and changes of blood metabolic substrates in Taekwondo compitition, Subjects as a T group were seven well-trained Taekwondo players. Control group was composed of seven healthy male students who taking Taekwondo club in D university. Data were analyzed by ANOVA with post hoc-test The 0.05 level of significance was as critical level for the study Result of this are as follows: Through Taekwondo competition it showed that average lactate concentration were increased by rotating round in both groups. the concenttiation of Glucose and F.F.A were increased by rotating round in Taekwondo competition. TG concentration was gradually increased until 2 round but at 3 round it was decreased in T group.

콩에서 발생하는 강낭콩일반모자이크바이러스(BCMV)와 땅콩위축바이러스(PSV)의 저항성 평가

이영훈, 윤영남, 강범규, 김현영, 최만수, 구성철, 김현태, 윤홍태, 이수헌, 백인열 忠北大學校 農業科學硏究所 2014 農業科學硏究 Vol.30 No.2

It has been reported several viral diseases in soybean. The occurrence of Bean common mosaic virus and Peanut stunt virus are able to induce severe problem because the main breeding target for viral disease was focused on Soybean mosaic virus. BCMV is a spcies of the genus Potyvirus of the family Potyviridae. BCMV reduces yield by as much as 80% and also adversely affects seed quality in common bean. BCMV has a worldwide distribution because of its high rates 35% of transmission via seeds produced by plants systemically infected prior to bloom. PSV is a species of the genus Cucumovirus of the family Bromoviridae. PSV has been reported to be economically damaging on beans worldwide. Although the virus is reportedly seed transmissible at very low rates, infected plants rarely produce pods with normal viable seeds. The most satisfactory management method of viral diseases such as BCMV and PSV is the use of resistant cultivars and healthy seed. For the overcome of genetic resistance by new virus such as BCMV and PSV, virus diseases monitoring and researches need to study deeply and continually. In this study, we conducted the resistance screen on BCMV and PSV for selection of resistance cultivars. We inoculated on 128 cultivars with PSV and BCMV respectively. These cultivars were classified through pathogenic response such as resistance, necrosis and susceptibility. In addition, 99 and 66 resistant cultivars were confirmed against PSV and BCMV respectively.

Duct-Occlud^(R)를 이용한 동맥관 개존의 비수술적 폐쇄에 대한 고찰

윤성관,박영봉 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.1

Background: Transcatheter coil occlusion of small to moderate-sized patent ductus arteriosus (PDA, <3.5 ㎜) is well established as a procedure of first choice in many institutions. We made an attempt to occlude the duct with retrievable coil device (Duct-Occlud^(R)) in 5 children with PDA, and reviewed the clinical aspects and follow-up results. Method: PDA occlusion with "Duct-Occlud^(R)" system was attempted with small to moderate sized PDA from January to Decembcr 2001. Five patients with a PDA(2 boys and 3 Girls: 4 to 48 months; 5.5 to 14 ㎏) were enrolled. The available size of the PDA ranged from 2.0㎜ to 4.0㎜. After estimation thp size of FDA was done by angiogram, retrievable coil device (Duct-occlud^(R)) was inserted through the femoral vein route. The angiocardiography was performed 15 minutes after the device implantation in order to document coil position and PDA occlusion. On the next day and 7 days later, the follow-up Doppler echocardiogram were examcd to assess PDA closure. And then, it continued at 6 months and 12 month later. The mean duration of follow-up was 8.5 months (2 to 12 months). Results: The QP/Qs was 1.51(1.39 to 1.9), mean diameter in aortic side of PDA was 3.34㎜(2.0㎜ to 4.0 ㎜). The one case was required repositioning of coil by faulty coil detaching from duct-occluded system, while the others were successful in first Procedure. Conclusion: The PDA occlusion in five cases were all successful. Duct-Occlud^(R) system is effective and safe method for percutaneous closure of small to moderate-sized PDAs. 배경: 재장착이 가능한 동맥관 개존 색전 폐쇄 기구인 Duct-Occlud^(R) system를 이용하여 5명의 작거나 중등도의 단순 동맥관 개존에 대한 비수술적 폐쇄술을 시도하였다. 위 시술을 시행받은 환아들의 임상 경과와 추적 검사 결과를 보고한다. 방법: 2001년 1월부터 2001년 12월까지 만 12개월동안 작거나 중등도의 크기를 가진 단순동맥관 개존 5례를 대상으로 하였다. 심혈관조영술고 동맥관의 크기를 측정한 후에 retrievable coil device(Duct-Occlud^(R) system)를 대퇴정맥으로 넣고 대동맥의 ampulla측, 폐동맥측의 순으로 막았다. 심혈관 조영과 심초음파 검사로 추적검사를 시행하였다. 결과: Qp/Qs는 1.51(1.39-1.90)였다. 동맥관의 모양은 conial, tubular 형태를 보였다. 동맥관의 폐동맥측 최소 직경은 1.82 mm(1.23-3.20 mm), 대동맥측 최소 직경 3.34 mm(2.00-4.00mm)였고, 동맥관의 길이는 매우 다양하여 5.88 mm(5.20-7.35 mm)로 측정되었다. 합병증은 없었고, 1례에서 시술의 마지막에 코일이 분리되지 않아 같은 크기의 다른 코일을 이용하여 재시술 하였다. 심혈관 조영술에서의 동맥관 혈류는 1례를 제외한 4례에서는 미량 있었고 1주 후에는 1례에서 남아있었으나 6개월 후에는 모두 잔존단락은 없어졌다. 결론: Duct-Occlud^(R) system에 의한 색전 폐쇄술은 작거나 중등도의 동맥관 개존에서 안전하고 효과적인 시술이라고 사료된다. 또한 delivery system의 크기가 작아서 혈관손상이 적으므로 영유아에서도 가능하다는 장점이 있다. 따라서 중등도 이하의 동맥관 개존에서 Duct-Occlud^(R) system은 안전하고 효과적으로 이용될 수 있으리라 판단된다.

민간영리 스포츠 시설로서의 수영장의 라이프 사이클과 경영전략에 관한 연구

윤영복,박준희,정용준 조선대학교 사범대학 부설 교과교육연구소 1998 敎科敎育硏究 Vol.1 No.1

We made a research on the sports facility managers who manage the commerical swinning center in seoul, Kwang Ju, Pusan and Taegu, The results are as follows: (1) The competive strategy of swimming center consists of inner-differentiation strategy, out-differentiation strategy and low cost strategy. (2) Inner-differentiation strategy is emphasized by the swimming center which sets the goal for growth maintenance. (3) Competitive stratgy of swimming center is dertermined by each stage in the life cycle theory ① Introduction stage : The emphasis of strategy is laid on inner-differentiation strategy. ② Growth stage : The emphasis of strategy is laid on both inner-differentiation strategy and out-differentiation strategy ③ Decline stage : The emphasis of strategy is laid on out-differentiation strategy with the aim to maintain.

首都圈 衛星都市의 住民福祉向上을 위한 市議會와 行政機關의 役割에 관한 硏究 : Centering Around Koyang-Shi Kyung Ki-Do Area. (京畿道 高揚市를 中心으로)

윤석달,박오화,함영훈,황정룡,허희영 한국항공대학교 1993 論文集 Vol.31 No.-

地方化時代의 到來로 高揚市는 많은 變化가 豫想되고 있다. 1980年부터 繼續的으로 論議되던 地方自治의 問題가 지금은 現實化되어 1991年 4月에는 基礎地方自治의 議會를 構成하고 6月에는 廣域自治團體의 議會를 構成하였고 머지않은 將來 에 地方自治團體의 長을 選出할 豫定이다. 앞으로 많은 施行錯誤가 있을 수 있겠으나 地方自治時代에 돌입한 것은 누구 도 否認 할 수 없는 사실이다. 1997年경의 住民構成은 1990年代初期의 高揚市에 居住하고 있던 原住民과 一山을 포함한 新高揚 開發地域에 90萬의 新 入住者로 구성될 것이며, 이러한 高揚市 住民構成의 變化는 地方自治에 커다란 衝擊要因으로 작용될 것이다. 新.原住民의 要求를 調和하는 問題는 여러 形態로 나타날 수 있으나 住民福祉라는 側面이 매우 강하게 대두될 것이다. 高揚市의 福祉活動은 生活保護者들을 위한 특수한 경우를 제외하고는 거의 전무한 상태이다. 地方自治制度가 어느정도 安定的인 국면으로 접어들면, 地域的 次元에서 市民 모두를 위한 福祉活動이 深度있게 展開되어야 할 것이다. 市行政機 關과 市議會는 兒童福祉, 婦女福祉, 老人福祉및 醫療福祉에 대한 現況울 把握하고 이에 대한 해결의 優先順位를 결정하 여 다가오는 人口의 增加에 따른 福祉需要를 충족시켜 나가야 할 것이다. 福祉需要에 대한 優先順位를 硏究者들이 제시하여 보면 託兒施設과 더불어 綜合病院施設을 擴充하여 市民들에게 奉仕 하는 태세를 體系化하여야 할 것이며 그밖에는 施設을 擴充하는 方式보다는 年齡과 性別 및 職業 등의 基準에 맞게 "프 로그램"을 積極的으로 開發하는 努力이 경주되어야 할 것이다. 그러으로써 量的인 意味에서 뿐만이 아니라 質的인 意味 에서 福祉活動을 展開할 수 있는 基盤을 造成할 수 있을 것이다. It is expected that Koyang City have lots of changes according to the emergence of Decentralization era. Nowdays local self-government has been realized since its disscussion in 1980. On april, 1991, the assembly of basic self-government was established, and the assembly of extensive self-government constructed on june, 1991. The chairman of local-government assembly is supposed to be elected in the new future. None can deny the beginning of local-government era inspite of potential trial and errors. Population structure in 1997 is expected to be composed of the existing civilians of Koyang City in early 1990's and about 0.90millions of new comers in new cities including llsan area, and he change of the city population will significant impacts on the self-government scheme of Koyang City. The problem to coordinate desires of existing civilians and that of new comers might be embodied in many kinds of aspects, but welfare-raising will be strengthed first of all. Existing welfare programme of Koyang City dosen't show any signigicant activities except the case of Green Card programme. It is desirable that whole-sideed welfare programme be perfomed by local levels in the stage of staionary self-government systems. Administrative institutions and assembly of city should survey and research the present situations of children welfare, female welfare, the old age welfare, and medical welfare, and decide their priorities to meet increasing desires coming from rapid increase of city-population. We, researchers, propose several outstanding problems by priority as follows; to expand medical institutions and public nursery schools accompanies by strenthening the attitude of government employees for public service, to develop various programmes in order to activate many exiting institutions more efficiently rather than to build new institutions needed, in consideration of ages, sex and occupations of their users. If these propositions accomplished the welfare programme will have cornerstone to enrich its activities as well as activities as well as enlarge it bounderies.

지구성운동후 혈청 LDH 활성 및 Isoenzyme 분포의 변화에 관한 연구

윤영학,김복주 대한스포츠의학회 1994 대한스포츠의학회지 Vol.12 No.1

The purpose of this study was to investigate changes of serum LDH, isoenzyme pattern and H/M ratio of the pre and post endurance exercise. Subjects as an athlete group were seven well-trained long distance male runners. Non-athlete group was composed of seven healthy male students who not taking any particular physical training. V˙O_2mas. was determined for each subject by administering a treadmill exercise test with Bruce protocol. The exercise intensities are decided by regresion equations between the percantage of V˙O_2masand speed (mph), grade(%) Subjects had engaged in tread mill exercise for 40minutes at 50% V˙O_2mas. exercise. The LDH isoenzymes assay were determined by the LDH isoenzyme electrophoresis procedure. Paired t-test was used to evaluate the difference of the pre and post exercise within group and between groups. The 0.05 level of significance was as critical leverl for the study. The results of the study are as follows: 1. At rest, Athlete group is higher in serum LDH activity and H/M ration than non-athlete group. 2. Serum LDH activity increased after endurance exercise. 3. After 50% V˙O_2mas. exercise, LDH_1 significantly increased in athlete and non-athlete group(P<0.01). H type(%) significantly increased in 50% V˙O_2mas. exercise (P<0.01).

CFS로 횡보강된 콘크리트 압축부재의 보강성능에 관한 실험적 연구

유영찬,임재형 국립7개대학공동논문집간행위원회 2003 공업기술연구 Vol.3 No.-

The attention of this paper is focused on the reinforcement capacity of the RC compressive member confined with CFS and the regression analysis is performed with the use of the previous experimental data. From the regression analysis, the main parameters for CFS confinement were proved to be CFS amounts of reinforcement and overlapping length plus confinement coefficient. The main parameters and confinement coefficient are as follows. 1) CFS amounts of reinforcement: confinement ratio 0.53(circle), 0.35-0.40(rectangle) 2) Overlapping length: 10cm to a half of a cylinder circumference 3) Transverse confinement coefficients: 2.4(circle), 1.03(rectangle) The analytical results through the regression analysis are determined that they correspond well with experimental ones carried out to verify the afore-mentioned parameters and confinement coefficient.

燃料節約을 위한 舶用中速機關의 最適運轉條件에 關하여 : 實習船 釜山 403號를 中心으로 With training ship "Busan 403"

尹錫勳,金鍾華,金永植 釜山水産大學校 1985 釜山水産大學 硏究報告 Vol.25 No.2

釜山水産大學 實習船 釜山 403號의 主機關인 中速디젤機關을 利用하여 機關 冷却水溫度와 給氣溫度를 변화시키며 機關性能 및 燃燒性을 考察한 結果 다음과 같은 結論을 얻었다. 1. ??를 높임에 따라 ??가 上昇하며 ?? 10℃ 上昇時 ??는 約 7.6℃ 上昇하였으며, ??를 60℃로 하여 運轉하는 경우에도 공기과잉율의 低下에 의하여 燃燒性이 不良해지는 현상은 일어나지 않았다. 2. ?? 增加時 O₂濃度 감소, CO₂濃度 增加의 현상이 나타났으며 ?? 40℃일 때 ?? 25℃ 上昇時 공기과잉율은 約 0.41程度 低下하였으나 이러한 현상은 ??가 增加할수록 둔화되었다. 3. ??가 上昇함에 따라 同一한 공기과잉율에서 이산화탄소 생성량이 增加하였으며 이는 同一한 條件에서 冷却水溫度의 上昇에 따라 燃燒性이 向上됨을 알 수 있다. 4. 馬力當 燃料消費率이 가장 적은 것은 負荷 100% BHP의 경우이며 이때 正味燃料消費率은 173.76gr/BHPㆍh이다. This investigation tries to find the better operating condition that the fuel oil is saved for the medium speed diesel engine installed on training ship "Busan" 403˝. This study observes the performance and combustibility of the engine under the condition for various temperature of cooling water and scavenging air. The combustibility increases with the increase of the cooling water temperature. Though the temperature of scavenging air rises to 60℃, the combustion of the engine is good in condition.