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      • SCOPUSKCI등재

        C3H 생쥐에서 자외선 B의 집중조사와 분할조사가 표피내 랑게르한스 세포의 회복에 미치는 영향

        구상완,한승경,박윤기,조무연 ( Sang Wahn Koo,Seung Kyung Hann,Yoon Kee Park,Moo Yon Cho ) 대한피부과학회 1991 대한피부과학회지 Vol.29 No.4

        N/A The Effect on the Recovery of Epidermal Langerhans Cells in C3H Mice after Single and Fractionated Exposure of Ultraviolet B Irradiation Sang-Wahn Koo, M.D., Seung Kyung Hann, M.D., Yoon-Kee Park, M.D., Moo Yon Cho, M.D. Department of Dermatology, Yonsei University College of Medicine Seoul, Korea The study was undertaken to see the recovery in epidermal Langerhans cells in relation to time after UVB irradiation through different amounts and ways of exposure in C3H mice. We irradiated the ears of C3H mice with UVB 200mJ/㎤ and 400mJ/㎤ in a single dose at one time and 5 fractionated doses for 5 days and 10 fractionated doses for 10 days and performed biopsies on the ears of the control and experimental groups after, 2, 7, 14, 21 days of irradiation and stained them by the immunoperoxidase method. The results are summarized as follows. 1. A more significant decrease in the number of Ia-positive epidermal Langerhans cells was observed in single-dose-exposed group than fractionated-dose-exposed groups on the second day of irradiation. 2. On the seventh day of exposure, the number of the Ia-positive epidermal cells in single-dose-exposed group returned to normal, but in fractionated-dose-exposed groups the number of Langerhans cells decreased most remarkably. 3. In fractionated-dose-exposed groups, the number of Langerhans cells returned to normal on the 14th or 21st day of expposure. (Kor J Dermatol 29(4) : 459-465, 1991)

      • 폐FRP로부터 친환경적 유리섬유 추출 공정 개발

        尹救永 弘益大學校 産業技術硏究所 2005 産業技術 Vol.15 No.-

        The trend of using FRP (Fiber Reinforced Plastics) that range of high mechanical strength and corrosion resistivity and superior molding is now widening. But FRP has a serious problem to be used as structure stuff nowadays. An annual wastes of FRP in Korea are more than 100,000 tons, but it is believed that the most of waste are been abolished without the appropriate treatment. It is fact that most of FRP wastes are depended on incineration or reclamation. Because it is made up of reinforced fiber glass, it is very difficult to break into pieces. By the disposing of waste FRP this way, it also occurs secondary problem such as air pollution. For these reasons, the research of FRP recycling field is now focusing on FRC(fiber reinforced concrete) that use disposed FRP. This study is to show a process of manufacturing and practical using for FRC from the waste FRP.

      • 성인 급성 신부전의 원인 및 예후인자 분석

        구영선,장윤경,양종오,강민규,황평주,김종학,나기량,이강욱,신영태 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.2

        Acute renal failure is a frequent complication in hospitalized patients and is strongly related to the mortality. The Clinical outcome and prognostic factors of acute renal failure(ARF) have been analyzed by many authors. The present study describes the etiologic and clinical aspects, as well as other factors related to mortality. All the patients suffering from acute renal failure admitted during the period of January 1993 - August 1998 were included in the study. The average age of the patients was 52±17 years and mortality rate was 24%. The causes of acute renal failure were hemorrhagic fever with renal syndrome(HFRS), sepsis, renal hypoperfusion, urinary tract obstruction, acute tubular necrosis, etc. The etiology of ARF was a significant prognostic factor on mortality in ARF. Other significant prognostic factors were oliguria, organ failure, use of vasoconstrictors, hypotension, serum bicarbonate, premorbid conditions, sepsis, neurologic complications, gastrointestinal bleeding. On the other hands, operation, sex, anemia, thrombocytopenia, hypoalbuminemia, BUN, serum creatinine, and hyperkalemia were not significant factors for the mortality. We conclude that major prognostic factors of acute renal failure arc premorbid conditions, sepsis and multiorgan failure, and they are responsible for persistent high mortality of acute renal failure despite of advances of medical care.

      • 신뢰성 향상을 위한 부품관리 연구

        尹救永 홍익대학교 산업기술연구소 2001 産業技術 Vol.11 No.-

        Reliability based optimum design for manufacturing systems is one of the most demanding field by manufactures. The manufacturing cost is the most dominant factor for company. Nevertheless the object is highly asked to be solved, the answer is not a simple one at all. Because the production process is usually very sophisticated and the production cost is combined with several part production process. Therefor traditional approach is mainly trying to reduce the failure vrate, but that is very costly method. Also that method hasn't know the relation between the cost of improving productivity and the cost of the control of failure.Here we used the Monte Carlo Simulation method for revealing the relation between the cost of failure and the control of that. We adopted the real process plan from a battery manufacturing company. Then the method is successfully applied to that process. Therefore We have very remarkable success to increase the productivity and reduce the control of failure. This simulation can be easily introduced to other manufacturing process and field These kinds of research will be an important area to the future work. Our methodology is going to increase our manufacturing flexibility and efficiency. It is our success that will continue to make us a leader in newly engineered study.

      • N-isopropylacrylamide에 기초한 공중합체의 합성과 팽윤 거동에 관한 연구

        윤구식,배민애 울산대학교 2002 자연과학논문집 Vol.11 No.2

        열에 민감한 poly(N-isopropylacrylamide)[poly(NIPAAm)], poly(N-isopropylacrylamide-co-acrylamide)[poly(NIPAAm-co-AAm)], poly(N-isopropylacrylamide-co-N.N-dimethylacrylamide)[poly(NIPAAm-co-DMAm)] 그리고 poly(N-isopropylacrylamide-co-N,N-diethylacrylamide)[poly(NIPAAm-co-DEAm)]을 가교제인 ethylene glycol dimethacrylate(EGDMA)와 개시제인 N,N-azobisisobutyronitrile(AIBN)을 사용하여 라디칼 중합으로 합성하였다. 공중합체의 팽윤 거동을 고분자의 친수성 및 공단량체의 조성에 따라 조사하였다. 공단량체가 더욱 친수성인 AAm과 공중합되어 있는 poly(NIPAAm-co-AAm)은 poly(NIPAAm)보다 팽윤비와 LCST가 높았으며, 단량체의 함량이 증가함에 따라 팽윤비와 LCST는 더욱 높아졌다. 반면에 단량체가 가장 소수성인 DEAm과의 공중합체 poly (NIPAAm-co-DMAm)은 팽윤비와 LCST가 가장 낮았으며, 공중합체에서 단량체 DEAm의 함량이 증가함에 따라 팽윤비와 LCST는 더욱 낮아졌다. 공중합체의 팽윤비는 공단량체의 친수성 순서와 같은 poly(NIPAAm-co-AAm)> poly(NIPAAm-co-DMAm)> poly(NIPAAm-co-DEAm)의 순이었으며, LCST 또한 같은 순서로 관찰되었다. Thermosensitive hydrogels of poly(N-isopropylacrylamide)[poly(NIPAAm)], poly(N-isopropylacrylamide-co-acrylamide)[poly(NIPAAm-co-AAm)], poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide)[poly(NIPAAm-co-DMAm)] and poly(N-isopropylacrylamide-co-N,N-diethylacrylamide)[poly(NIPAAm-co-DEAm)] were prepared by free radical copolymerization with ethylene glycol dimethacrylate(EGDMA) as crosslinking agent. The swelling behavior of hydrogels was investigated as a function of hydrophilicity and composition of copolymer. The swelling ratio and LCST of poly(NIPAAm-co-AAm) were much higher than that of poly(NIPAAm), and as the AAm content increased the swelling ratio and LCST were increased. On the other hand, in the poly (NIPAAm-co-DMAm) which was prepared from NIPAAm and hydrophobic comonomer, DEAm, the swelling ratio and LCST of copolymer were decreased with increasing of DEAm content. The swelling ratio of these copolymers were poly(NIPAAm-co-AAm)> poly(NIPAAm-co-DMAm)> poly(NIPAAm-co-DEAm) in decreasing order. Also, the LCST was observed in same order.

      • 운동시의 항산화제 효과에 관한 연구실태분석

        구민성,김윤희,여남회 東亞大學校附設스포츠科學硏究所 2001 스포츠科學硏究論文集 Vol.19 No.-

        The purpose of this study was to investigate literature study of the effect of antioxidant during exercise. The study material were five journal of exercise science, master and doctoral theses, and antioxidants. Total thirty-five articles were selected this study. This study demonstrated that the mechanism of free radical and antioxidant did not find out during exercise and recovery. High intensity exercise or training produced on excess of free radical, but low-intensity exercise and antioxidant supplement were not. These results suggest that don’t forget Cooper’s advices: “Exercise must be at the center of any effective antioxidant action plan.” The reason; without regular exercise, your body’s internal defense against free radicals including natural endogenous antioxidants like SOD, GSH, Catalase may become too fragile for supplement to have their full effect.

      • KCI등재
      • 情報檢索效率에 관한 硏究

        尹龜鎬 韓國圖書館學會 1981 圖書館學 Vol.8 No.1

        Retrieval effectiveness in the principal criterion for measuring the performance of an information retrieval system. The effectiveness of a retrieval system depends primarily on the extent to which it can retrieve wanted documents without retrieving unwanted ones, So, ultimately, effectiveness is a function of the relevant and nonrelevant documents retrieved. Consequently, "relevance" of information to the user's request has become one of the most fundamental concept encountered in the theory of information retrieval. Although there is at present no consensus as to how this notion should be defined, relevance has been widely used as a meaningful quantity and an adequate criterion for measures of the evaluation of retrieval effectiveness. The recall and precision among various parameters based on the "two-by-two" table(or, contingency table) were major considerations in this paper, because it is assumed that recall and precision are sufficient for the measurement of effectiveness. Accordingly, different concepts of "relevance" and "pertinence" of documents to user requests and their proper usages were investigated even though the two terms have unfortunately been used rather loosely in the literature. In addition, a number of variables affecting the recall and precision values were discussed. Some conclusions derived from this study are as follows: Any notion of retrieval effectiveness is based on "relevance" which itself is extremely difficult to define. Recall and precision are valuable concepts in the study of any information retrieval system. They are, however, not the only criteria by which a system may be judged. The recall-precision curve represents the average performance of any given system, and this may vary quite considerably in particular situations. Therefore, it is possible to some extent to vary the indexing policy, the indexing policy, the indexing language, or the search methodology to improve the performance of the system in terms of recall and precision. The "inverse relationship" between average recall and precision could be accepted as the "fundamental law of retrieval", and it should certainly be used as an aid to evaluation. Finally, there is a limit to the performance(in terms of effectiveness) achievable by an information retrieval system. That is : "Perfect retrieval is impossible."

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